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Protein

Testis-expressed protein 15

Gene

Tex15

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Required during spermatogenesis for normal chromosome synapsis and meiotic recombination in germ cells. Necessary for formation of DMC1 and RAD51 foci on meiotic chromosomes, suggesting a specific role in DNA double-stranded break repair.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processDifferentiation, DNA damage, DNA repair, Meiosis, Spermatogenesis

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Testis-expressed protein 15By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Tex15Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1934816 Tex15

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Viable with no gross phenotype. Male mice are infertile with significantly reduced testis size, while females are fertile. Severe depletion of germ cells in seminiferous tubules and epididymal tubules, due to meiotic arrest.1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004354841 – 2785Testis-expressed protein 15Add BLAST2785

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F8VPN2

PRoteomics IDEntifications database

More...
PRIDEi
F8VPN2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
F8VPN2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
F8VPN2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Detected in testis and ovary, and at lower levels in lung and brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000009628 Expressed in 141 organ(s), highest expression level in female gonad

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
F8VPN2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
F8VPN2 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000009772

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
F8VPN2

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F8VPN2

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi202 – 334Ser-richPROSITE-ProRule annotationAdd BLAST133

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TEX15 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IESA Eukaryota
ENOG410XSS9 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006260

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000169836

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG075407

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
F8VPN2

Identification of Orthologs from Complete Genome Data

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OMAi
AFCELQN

Database of Orthologous Groups

More...
OrthoDBi
4693at2759

TreeFam database of animal gene trees

More...
TreeFami
TF332375

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026616 TEX15
IPR032765 TEX15_dom

The PANTHER Classification System

More...
PANTHERi
PTHR22380 PTHR22380, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15326 TEX15, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1Curated (identifier: F8VPN2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MTYFFIYVST ERACSLNNCT IAKRIGKGKD ATVIFEHFRK PVDPFVQENC
60 70 80 90 100
PCKALNSEMG PFSSDTSSSY GNVQNGNNSV LEAYNRQTEN SSNLRDASQV
110 120 130 140 150
YTHNSGFSFI PTGNTASGNG DLFSVTYLRS ILSSISAAFP SHNNTGSSTV
160 170 180 190 200
ITSKLIKDPR LMKREQSMRN KSDTAGLSDV LPLDKSLGCG DSQIKLTCMP
210 220 230 240 250
TSSISSSEVP ADNTITSCLN ASCFKFSSES SHYQAHNSSS KGHDCIASSS
260 270 280 290 300
IAVTEQFKEQ HSSSFPSSLS NAFSDVRKQK HSEEQVQRAQ MRSNVPVLTA
310 320 330 340 350
LSSESRNSDE SENTCSNDSQ GHFSQESPSS DINSIYKVGH QMSTVFPAQK
360 370 380 390 400
KGNLCEYIQD TGMMRASIST EDSTKDGVNH TWCKETVLSN ETVSSPIDNS
410 420 430 440 450
NTLYQEHKEG GNLNSLSGNC EKIGVTHKLQ VPKFPISSTG DKNELYRAAL
460 470 480 490 500
ELECSLTPTI ECLSQKYPQH SLEHEDNTNF AMTQGLIELK TVQNNQNFGN
510 520 530 540 550
ILSDAFQEAK DVPLASEKLI DRVISSAAID ISLDSSVCNI IGEYTCVRRE
560 570 580 590 600
NENGEASPYN CHKEEASRVK DGVQDHSLSY DAELSCDLNL KINLQEQRDD
610 620 630 640 650
KNPNEAKEHN TDNINGSEKQ DCLANDHFTN IVEMREIKSN TEVEILNSEE
660 670 680 690 700
CFTFNSFRGK NGKPAETASS ESEAVEQRHA PNDQRGLEHL VSSFPEIEGS
710 720 730 740 750
SVCVASNATK QIVGTTVLTV STSLGDHQKD ELKEICSSES SDLGLVKHSI
760 770 780 790 800
SECEIDTDKD KLQDFHQLVN ENSALKTGLG SEIEVDLEHD NASVFQQNMH
810 820 830 840 850
SQGNDLCEEF ELYESLKSRI DWEGLFGSSY EEIESSSFAR REGTDQHSST
860 870 880 890 900
ECNCVSFCSQ DKRELHNPIF LPDLQVTITN LLSLRISPTD ESLELKDNFY
910 920 930 940 950
KQVTESTEPE TNKEGNASGF GMCSQPSGEN SSFSCANKFG NSVQESGDVS
960 970 980 990 1000
KSESSHSSNS SHNTHVDQGS GKPNNDSLST EPSNVTVMND KSKCPTKSKP
1010 1020 1030 1040 1050
VFNDTRNKKD MQSRSSKRTL HASSSRGQNI ANKDLREHET HEKKRRPTSH
1060 1070 1080 1090 1100
GSSDRFSSLS QGRIKTFSQS EKHIRNVLNI LNNEASLCKS KHLSRKLNKA
1110 1120 1130 1140 1150
VLHLKKAHRR VHTSLQLISK VGQKRKGPLP KAYAVIHNNF WESCDHQGDS
1160 1170 1180 1190 1200
LMSERRYSKH FLSKRKYDKQ GDKRFLRFDI EESLTPVSKH RLYRTNRERI
1210 1220 1230 1240 1250
AECLSNEVMS GHVSSSLTTF HVREFCDEEQ FPEPQLPLAY TSQSISQLEY
1260 1270 1280 1290 1300
TNSIVGNESS SELEHFSETS GNMLDPKETL TEKEYQTHTQ LCNSDSAKLK
1310 1320 1330 1340 1350
NHTTHSIRDI AKECNSEDKT VLCESNPVYL SFIKENTSHS PDKSYDSNCK
1360 1370 1380 1390 1400
ANTDIHISVL GSKKKHILSV DIYEQDNCVS DGVKSGEAIF PIEKCTVPME
1410 1420 1430 1440 1450
TTSSIPTENI ASKSYTIPPV SSILVTAGEE ESSVGENGLF DVNENEMNIT
1460 1470 1480 1490 1500
MHSKLDLTSV TEESKICKKN MKNLSCNDSS MLLKENITGP SKRYMAKYIE
1510 1520 1530 1540 1550
EEKIRKIEQA VYKKIITEGS PISFKYKSQN KILKEKSFHV NKKIITNNLT
1560 1570 1580 1590 1600
DSHLSIKNST VDTIALKDIP NQLKERKEAG QIKVNNNSHS DCLSKPAIVE
1610 1620 1630 1640 1650
TNHRPVLHGN PKVATLQKEL KEHRSPNYTS HVTELSQILQ RADEAASLQI
1660 1670 1680 1690 1700
LEEETKLCQN ILPLFVQAFE RQQECSIDQI LISRKLLVEQ NLWNNCRLKL
1710 1720 1730 1740 1750
KPCAVDTWVE LQMAMETIQF IENKKRFLEG KPTFRSLLWY DESLYSELLR
1760 1770 1780 1790 1800
RPRGYQLQSN FYPGFQGRLK YNAFCELQNY HNQLVEFLTE TKKENNSYYA
1810 1820 1830 1840 1850
LLKYKRQINE CEAIMKHYSD CFDFCLSVPF ACGVNFGDSL GDLETLRKST
1860 1870 1880 1890 1900
LKLISVPGGS PKVHSYPGKK DHLWIIIEIV SSKVSFIKSN EEISIKICLY
1910 1920 1930 1940 1950
GLEHIYFDAA KSLVWKEKSC SLPKKHSEKN REMEEINERA FSKLKKIYDV
1960 1970 1980 1990 2000
LSKGLNNEPT SIGLQEDAII ASKQSTLGSI SNCRLNKAWL SYPDISCVGE
2010 2020 2030 2040 2050
ILDQAKSADL EELQGLTLRC TDHLEILKKY FQMLQEDNID NIFIMEENVL
2060 2070 2080 2090 2100
DMLSNHNLGA VILKPEAIEI YIEIVMISET IHYLKNLIAK KLHNQRFRGM
2110 2120 2130 2140 2150
LWFDWSLLPE LIGCQEEVVS LSVGDTQTHC LWKLVETAIS VLKKELAVIY
2160 2170 2180 2190 2200
EYGEASNCSY ALHLFYRELK ELTGVKRLLN NSKYSVSTYI DLVPHTASVN
2210 2220 2230 2240 2250
FGNTVAELEH NYKQFFLLLK NVMSVPQKDF GKMVHIIKVM KTIEHMKLLS
2260 2270 2280 2290 2300
AKDTKLSTHL LFLQMLRNKR NALQQNRQEK METPVTEPGE DSSQPGVSEQ
2310 2320 2330 2340 2350
TPPGTECTVK NISDSSKKRP VTADTCEVSQ GKGNTDTVPS WKKQKVTMKD
2360 2370 2380 2390 2400
VGNIQTVSKH PSTTGSPPND ENKIGSNSSD SLKSISASPE VVKRQSSVLG
2410 2420 2430 2440 2450
SVSPAESVQD TCTPKSESKV EPTDSLPDSL ASLTEQQENS NVIEKRNGNS
2460 2470 2480 2490 2500
SVAETNDKKD CPLVTCDQKD IDASYSPDHT PAQESHKTPV DHTQISPSNL
2510 2520 2530 2540 2550
TAGNDDPLVP DASLLSVSAS QSEKDVYLSG TDFHHENNKI LNLSTEDCTG
2560 2570 2580 2590 2600
TSSPEPVCIK DKISVLQVDK TQPIKSESPK KSMTDAPNPN TAPFGSYGNS
2610 2620 2630 2640 2650
ALNVNGTVQH THSEQNSKVL TQKVGTSRNI PPQSACSPVH NSSAHSFGTS
2660 2670 2680 2690 2700
YPYYSWCFYQ YSSSNGTAVT HTYQGMTAYE IQQPPPPVLT TVASTVQSTH
2710 2720 2730 2740 2750
FNRSYSEHFS YFPGQPQANS FNPGNGYFPS HTPVSYNYQQ PVYSQFASHQ
2760 2770 2780
PVPQATYPYP PNPGAPPQVP WTYAPWQQNP FLRRP
Length:2,785
Mass (Da):311,280
Last modified:September 21, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0A9D67F7B91591D2
GO
Isoform 2Curated (identifier: F8VPN2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-10: MTYFFIYVST → MDAEASAGKK...FSSTGFPKRL

Note: No experimental confirmation available.Curated
Show »
Length:3,035
Mass (Da):339,756
Checksum:iEEA425504FBC5341
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PY31E9PY31_MOUSE
Testis-expressed protein 15
Tex15
1,279Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
M0QWY2M0QWY2_MOUSE
Testis-expressed protein 15
Tex15
323Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
D3YVF5D3YVF5_MOUSE
Testis-expressed protein 15
Tex15
148Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti693S → T in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti792A → G in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti1169K → R in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti1826L → P in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti1939R → S in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti2589P → L in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti2626T → P in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti2678A → T in AAK31968 (PubMed:11279525).Curated1
Sequence conflicti2765A → V in AAK31968 (PubMed:11279525).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0581011 – 10MTYFFIYVST → MDAEASAGKKFTIPKIRRTT EKVYLSSCYTNTREYGFIHG TLKQCRLDMSCDLQFTWQFG ETKLVRNEYLEKQFAAKRSE MREGGRHSRELEEHFCFLAL PQADVMDVYQNGLSVGTSPL RILGNPLLGVYLCRHVDIAL SHACSRSVAVESIMIFKVLF GRIKKIQPSMDKNKVSLDPS PNFDCHMSRNMPSLKDTIEL QAYNSMVYFYEYDYFSRPVD KPRQCLPYAIVTVKCIGQKA GNGQLITSLRFSSTGFPKRL in isoform 2. 10

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AF285589 mRNA Translation: AAK31968.1
AC117807 Genomic DNA No translation available.
AC139025 Genomic DNA No translation available.
AK132667 mRNA Translation: BAE21290.1
AK143304 mRNA Translation: BAE25339.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS22232.1 [F8VPN2-1]

NCBI Reference Sequences

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RefSeqi
NP_113551.2, NM_031374.2 [F8VPN2-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Mm.280624
Mm.488030

Genome annotation databases

Ensembl eukaryotic genome annotation project

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Ensembli
ENSMUST00000009772; ENSMUSP00000009772; ENSMUSG00000009628 [F8VPN2-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
104271

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
mmu:104271

UCSC genome browser

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UCSCi
uc009lkc.1 mouse [F8VPN2-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF285589 mRNA Translation: AAK31968.1
AC117807 Genomic DNA No translation available.
AC139025 Genomic DNA No translation available.
AK132667 mRNA Translation: BAE21290.1
AK143304 mRNA Translation: BAE25339.1
CCDSiCCDS22232.1 [F8VPN2-1]
RefSeqiNP_113551.2, NM_031374.2 [F8VPN2-1]
UniGeneiMm.280624
Mm.488030

3D structure databases

ProteinModelPortaliF8VPN2
SMRiF8VPN2
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000009772

PTM databases

iPTMnetiF8VPN2
PhosphoSitePlusiF8VPN2

Proteomic databases

PaxDbiF8VPN2
PRIDEiF8VPN2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000009772; ENSMUSP00000009772; ENSMUSG00000009628 [F8VPN2-1]
GeneIDi104271
KEGGimmu:104271
UCSCiuc009lkc.1 mouse [F8VPN2-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
56154
MGIiMGI:1934816 Tex15

Phylogenomic databases

eggNOGiENOG410IESA Eukaryota
ENOG410XSS9 LUCA
GeneTreeiENSGT00390000006260
HOGENOMiHOG000169836
HOVERGENiHBG075407
InParanoidiF8VPN2
OMAiAFCELQN
OrthoDBi4693at2759
TreeFamiTF332375

Miscellaneous databases

Protein Ontology

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PROi
PR:F8VPN2

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000009628 Expressed in 141 organ(s), highest expression level in female gonad
ExpressionAtlasiF8VPN2 baseline and differential
GenevisibleiF8VPN2 MM

Family and domain databases

InterProiView protein in InterPro
IPR026616 TEX15
IPR032765 TEX15_dom
PANTHERiPTHR22380 PTHR22380, 1 hit
PfamiView protein in Pfam
PF15326 TEX15, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTEX15_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F8VPN2
Secondary accession number(s): Q3UPQ6, Q3V162, Q99MV3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 17, 2016
Last sequence update: September 21, 2011
Last modified: January 16, 2019
This is version 47 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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