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Protein
Submitted name:

Bromodomain adjacent to zinc finger domain protein 2A

Gene

Baz2a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Bromodomain adjacent to zinc finger domain protein 2AImported
Gene namesi
Name:Baz2aImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:2151152 Baz2a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000040054 Expressed in 346 organ(s), highest expression level in blood
GenevisibleiF8VPM0 MM

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliF8VPM0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini536 – 607MBDInterPro annotationAdd BLAST72
Domaini837 – 902DDTInterPro annotationAdd BLAST66
Domaini1660 – 1710PHD-typeInterPro annotationAdd BLAST51
Domaini1792 – 1862BromoInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili697 – 717Sequence analysisAdd BLAST21
Coiled coili737 – 775Sequence analysisAdd BLAST39

Keywords - Domaini

BromodomainPROSITE-ProRule annotationSAAS annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1245 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00930000150850
KOiK15224
OMAiRSGWWWI

Family and domain databases

CDDicd05503 Bromo_BAZ2A_B_like, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR017956 AT_hook_DNA-bd_motif
IPR037374 BAZ2A/B_Bromo
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR018501 DDT_dom
IPR016177 DNA-bd_dom_sf
IPR001739 Methyl_CpG_DNA-bd
IPR028940 TIP5
IPR028942 WHIM1_dom
IPR028941 WHIM2_dom
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR22880:SF141 PTHR22880:SF141, 1 hit
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF02791 DDT, 1 hit
PF01429 MBD, 1 hit
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
PF15613 WSD, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00384 AT_hook, 4 hits
SM00297 BROMO, 1 hit
SM00571 DDT, 1 hit
SM00391 MBD, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF54171 SSF54171, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS50827 DDT, 1 hit
PS50982 MBD, 1 hit
PS50016 ZF_PHD_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

F8VPM0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEANDHFNFT GLPPAPAASG LKPSPSSGEG LYTNGSPMNF PQQGKSLNGD
60 70 80 90 100
VNVNGLSTVS HTTTSGILNS APHSSSTSHL HHPNVAYDCL WNYSQYPSAN
110 120 130 140 150
PGNNLKDPPL LSQFPGGQYP LNGILGGNRQ PSSPSHNTNL RAGSQEFWAN
160 170 180 190 200
GTQSPMGLNF DSQELYDSFP DQNFEVMPNG PPSFFTSPQT SPMLGSSIQT
210 220 230 240 250
FAPSQDVSSD IHPDEAAEKE LTSVVAENGT GLVGSLELEE EQPELKMCGY
260 270 280 290 300
NGSVSSVESL HQEVSVLVPD PTVSCLDDPS HLPDQLEDTP ILSEDSLEPF
310 320 330 340 350
DSLAAEPVSG SLYGIDDAEL MGAEDKLPLE GNPVISALDC PALSNANAFS
360 370 380 390 400
LLADDSQTSA SIFVSPTSPP VLGESVLQDN SFGLNSCSDS EQEEIETQSS
410 420 430 440 450
NFQRPLTEPA PDQPPSTQLH PAVSPTASPA ASLTASAEIS PAVSPVASSP
460 470 480 490 500
VPPEVFVAVS PASSPALPAI SLEASMTTPV TSPQGSPEPS PAAAFQTVSP
510 520 530 540 550
ARKNVSSAPK ARADREETTG GAVAVSGSGD VLKRRIATPE EVRLPLQHGW
560 570 580 590 600
RREVRIKKGS HRWQGETWYY GPCGKRMKQF PEVIKYLSRN VVHSVRREHF
610 620 630 640 650
SFSPRMPVGD FFEERDTPEG LQWVQLSAEE IPSRIQAITG KRGRPRNNEK
660 670 680 690 700
AKNKEVPKVK RGRGRPPKIK MPELLNKTDN RLPKKLETQE ILSEDDKAKM
710 720 730 740 750
TKNKKKMRQK VQRGESQTPV QGQARNKRKQ DTKSLKQKDT KKKLKAEKEK
760 770 780 790 800
MKTKQEKLKE KVKREKKEKV KAKGKEGPRA RPSCRADKTL ATQKRLEEQQ
810 820 830 840 850
RQQAILEEMK KPTEDMCLSD HQPLPDFTRI PGLTLSSRAF SDCLTIVEFL
860 870 880 890 900
HSFGKVLGFD LTKDVPSLGV LQEGLLCQGD SLDKVQDLLV RLLKAALHDP
910 920 930 940 950
GLPPYCQSLK ILGEKMSEIP LTRDNVSEIL RCFLMAYRVE PSFCDSLRTQ
960 970 980 990 1000
PFQAQPPQQK AAILAFLVHE LNSSTIIINE IDKTLESVSS CRKNKWIVEG
1010 1020 1030 1040 1050
RLRRLKTALA KRTGRPEVMM EGAEDGLGRR RSSRIMEETS GIEEEEEEEN
1060 1070 1080 1090 1100
TTAVHGRRGR KEGEIDVAAS SIPELERHIE KLSKRQLFFR KKLLHSSQML
1110 1120 1130 1140 1150
RAVSLGQDRY RRHYWVLPYL AGIFVEGSEG STVTEDEIKQ ETESLMEVVT
1160 1170 1180 1190 1200
STPSSARASV KRELTGSNAS TSPARSRGRP RKPKPGSLQP QHLQSTIREC
1210 1220 1230 1240 1250
DSEQAQTQVH PEPQPQLQAP TQPHLQPSSG FLEPEGSPFS LGQSQHDLSQ
1260 1270 1280 1290 1300
SAFLSWLSQT QSHNSLLSSS VLTPDSSPGK LDSAPSQSLE EPEPDEAQSC
1310 1320 1330 1340 1350
PGPQGPWFNF SAQIPCDAAP TPPPAVSEDQ PTPSLQLLAS SKPMNTPGAA
1360 1370 1380 1390 1400
NPCSPVQLSS THLPGGTPKR LSGDSEEMSQ SPTGLGQPKR RGRPPSKFFK
1410 1420 1430 1440 1450
QVEQHYLTQL TAQPIPPEMC SGWWWIRDPE TLDVLLKALH PRGIREKALH
1460 1470 1480 1490 1500
KHLSKHKDFL QEVCLQPLTD PIFEPNELPA LEEGVMSWSP KEKTYETDLA
1510 1520 1530 1540 1550
VLQWVEELEQ RVVLSDLQIR GWTCPTPDST REDLTYCEHL PDSPEDIPWR
1560 1570 1580 1590 1600
GRGREGTVPQ RQNNNPLDLA VMRLAVLEQN VERRYLREPL WAAHEVVVEK
1610 1620 1630 1640 1650
ALLSTPNGAP DGTSTEISYE ITPRVRVWRQ TLERCRSAAQ VCLCMGQLER
1660 1670 1680 1690 1700
SIAWEKSVNK VTCLVCRKGD NDEFLLLCDG CDRGCHIYCH RPKMEAVPEG
1710 1720 1730 1740 1750
DWFCAVCLSQ QVEEEYTQRP GFPKRGQKRK SSFPLTFPEG DSRRRMLSRS
1760 1770 1780 1790 1800
RDSPAVPRYP EDGLSPPKRR RHSMRSHHSD LTFCEIILME MESHDAAWPF
1810 1820 1830 1840 1850
LEPVNPRLVS GYRRVIKNPM DFSTMRERLL RGGYTSSEEF AADALLVFDN
1860 1870 1880
CQTFNEDDSE VGKAGHVMRR FFESRWEEFY QGKQANL
Length:1,887
Mass (Da):209,406
Last modified:September 21, 2011 - v1
Checksum:i0E4D59B387C60A8F
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q91YE5BAZ2A_MOUSE
Bromodomain adjacent to zinc finger...
Baz2a Kiaa0314, Tip5
1,889Annotation score:
E9Q374E9Q374_MOUSE
Bromodomain adjacent to zinc finger...
Baz2a
1,888Annotation score:
A0A1W2P6X9A0A1W2P6X9_MOUSE
Bromodomain adjacent to zinc finger...
Baz2a
1,890Annotation score:
A0A1W2P6L0A0A1W2P6L0_MOUSE
Bromodomain adjacent to zinc finger...
Baz2a
763Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131120 Genomic DNA No translation available.
AC166817 Genomic DNA No translation available.
RefSeqiNP_473419.2, NM_054078.2
XP_006513177.1, XM_006513114.2
XP_011241587.1, XM_011243285.2
XP_011241588.1, XM_011243286.2
UniGeneiMm.252213

Genome annotation databases

EnsembliENSMUST00000045621; ENSMUSP00000044359; ENSMUSG00000040054
ENSMUST00000220049; ENSMUSP00000151961; ENSMUSG00000040054
GeneIDi116848
KEGGimmu:116848
UCSCiuc007hlj.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131120 Genomic DNA No translation available.
AC166817 Genomic DNA No translation available.
RefSeqiNP_473419.2, NM_054078.2
XP_006513177.1, XM_006513114.2
XP_011241587.1, XM_011243285.2
XP_011241588.1, XM_011243286.2
UniGeneiMm.252213

3D structure databases

ProteinModelPortaliF8VPM0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

DNASUi116848
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000045621; ENSMUSP00000044359; ENSMUSG00000040054
ENSMUST00000220049; ENSMUSP00000151961; ENSMUSG00000040054
GeneIDi116848
KEGGimmu:116848
UCSCiuc007hlj.1 mouse

Organism-specific databases

CTDi11176
MGIiMGI:2151152 Baz2a

Phylogenomic databases

eggNOGiKOG1245 Eukaryota
COG5076 LUCA
GeneTreeiENSGT00930000150850
KOiK15224
OMAiRSGWWWI

Miscellaneous databases

ChiTaRSiBaz2a mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000040054 Expressed in 346 organ(s), highest expression level in blood
GenevisibleiF8VPM0 MM

Family and domain databases

CDDicd05503 Bromo_BAZ2A_B_like, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR017956 AT_hook_DNA-bd_motif
IPR037374 BAZ2A/B_Bromo
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR018501 DDT_dom
IPR016177 DNA-bd_dom_sf
IPR001739 Methyl_CpG_DNA-bd
IPR028940 TIP5
IPR028942 WHIM1_dom
IPR028941 WHIM2_dom
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PANTHERiPTHR22880:SF141 PTHR22880:SF141, 1 hit
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF02791 DDT, 1 hit
PF01429 MBD, 1 hit
PF00628 PHD, 1 hit
PF15612 WHIM1, 1 hit
PF15613 WSD, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00384 AT_hook, 4 hits
SM00297 BROMO, 1 hit
SM00571 DDT, 1 hit
SM00391 MBD, 1 hit
SM00249 PHD, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF54171 SSF54171, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS50827 DDT, 1 hit
PS50982 MBD, 1 hit
PS50016 ZF_PHD_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8VPM0_MOUSE
AccessioniPrimary (citable) accession number: F8VPM0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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