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Protein
Submitted name:

Apoptotic protease-activating factor 1

Gene

APAF1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Apoptotic protease-activating factor 1Imported
Gene namesi
Name:APAF1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 12

Organism-specific databases

EuPathDBiHostDB:ENSG00000120868.13
HGNCiHGNC:576 APAF1

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000120868

PTM / Processingi

Proteomic databases

MaxQBiF8VNZ0
PeptideAtlasiF8VNZ0
PRIDEiF8VNZ0

Expressioni

Gene expression databases

BgeeiENSG00000120868
ExpressionAtlasiF8VNZ0 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliF8VNZ0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 90CARDInterPro annotationAdd BLAST90

Phylogenomic databases

eggNOGiKOG4155 Eukaryota
KOG4658 Eukaryota
ENOG410XP3K LUCA
GeneTreeiENSGT00920000149054

Family and domain databases

CDDicd08323 CARD_APAF1, 1 hit
InterProiView protein in InterPro
IPR037963 APAF1_CARD_dom
IPR001315 CARD
IPR011029 DEATH-like_dom_sf
PfamiView protein in Pfam
PF00619 CARD, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50209 CARD, 1 hit

Sequencei

Sequence statusi: Complete.

F8VNZ0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAKARNCLL QHREALEKDI KTSYIMDHMI SDGFLTISEE EKVRNEPTQQ
60 70 80 90 100
QRAAMLIKMI LKKDNDSYVS FYNALLHEGY KDLAALLHDG IPVVSSSSGK
110 120 130
DSVSGITSYG LYPLYLLSLC YQNCFGFVLL
Length:130
Mass (Da):14,688
Last modified:September 21, 2011 - v1
Checksum:i54BFDE7EA9C0FAE8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011248 Genomic DNA No translation available.
AC013283 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000547743; ENSP00000450175; ENSG00000120868
UCSCiuc058scx.1 human

Similar proteinsi

Entry informationi

Entry nameiF8VNZ0_HUMAN
AccessioniPrimary (citable) accession number: F8VNZ0
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 20, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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