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UniProtKB - F8VNQ3 (F8VNQ3_HUMAN)

Entry version 80 (02 Dec 2020)
Sequence version 1 (21 Sep 2011)
Previous versions | rss
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Protein
Submitted name:

Teneurin-2

Gene

TENM2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesionARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Teneurin-2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TENM2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000145934.15

Human Gene Nomenclature Database

More...HGNCi		HGNC:29943, TENM2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei184 – 205HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Cell membraneARBA annotation, Cell projectionARBA annotation, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000145934

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi392 ↔ 401PROSITE-ProRule annotation
Disulfide bondi426 ↔ 435PROSITE-ProRule annotation
Disulfide bondi474 ↔ 484PROSITE-ProRule annotation
Disulfide bondi493 ↔ 502PROSITE-ProRule annotation
Disulfide bondi538 ↔ 548PROSITE-ProRule annotation
Disulfide bondi555 ↔ 564PROSITE-ProRule annotation
Disulfide bondi578 ↔ 588PROSITE-ProRule annotation
Disulfide bondi599 ↔ 608PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...MaxQBi		F8VNQ3

PeptideAtlas

More...PeptideAtlasi		F8VNQ3

PRoteomics IDEntifications database

More...PRIDEi		F8VNQ3

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		28188

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000145934, Expressed in left ventricle myocardium and 175 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		F8VNQ3, baseline and differential

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 184Teneurin N-terminalInterPro annotationAdd BLAST184
Domaini366 – 402EGF-likeInterPro annotationAdd BLAST37
Domaini404 – 436EGF-likeInterPro annotationAdd BLAST33
Domaini470 – 503EGF-likeInterPro annotationAdd BLAST34
Domaini534 – 565EGF-likeInterPro annotationAdd BLAST32
Domaini574 – 609EGF-likeInterPro annotationAdd BLAST36

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni44 – 80DisorderedSequence analysisAdd BLAST37

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the tenascin family. Teneurin subfamily.ARBA annotation

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT01010000222317

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000229_0_0_1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.120.10.30, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011042, 6-blade_b-propeller_TolB-like
IPR008969, CarboxyPept-like_regulatory
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR011044, Quino_amine_DH_bsu
IPR022385, Rhs_assc_core
IPR027689, Ten-2/3
IPR009471, Ten_N
IPR028916, Tox-GHH_dom
IPR006530, YD

The PANTHER Classification System

More...PANTHERi		PTHR11219:SF8, PTHR11219:SF8, 2 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF06484, Ten_N, 1 hit
PF15636, Tox-GHH, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00181, EGF, 8 hits
SM00179, EGF_CA, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49464, SSF49464, 1 hit
SSF50969, SSF50969, 1 hit

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00022, EGF_1, 6 hits
PS01186, EGF_2, 5 hits
PS50026, EGF_3, 5 hits
PS51361, TENEURIN_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F8VNQ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVSPPLLIIS VAGTIECKPD HLLWRPGSTS PQSVSFLHGK VVMESLGPPN 
        60         70         80         90        100
HHSQSTLRPP LPPPHNHTLS HHHSSANSLN RNSLTNRRSQ IHAPAPAPND 
       110        120        130        140        150
LATTPESVQL QDSWVLNSNV PLETRHFLFK TSSGSTPLFS SSSPGYPLTS 
       160        170        180        190        200
GTVYTPPPRL LPRNTFSRKA FKLKKPSKYC SWKCAALSAI AAALLLAILL 
       210        220        230        240        250
AYFIVPWSLK NSSIDSGEAE VGRRVTQEVP PGVFWRSQIH ISQPQFLKFN 
       260        270        280        290        300
ISLGKDALFG VYIRRGLPPS HAQYDFMERL DGKEKWSVVE SPRERRSIQT 
       310        320        330        340        350
LVQNEAVFVQ YLDVGLWHLA FYNDGKDKEM VSFNTVVLDS VQDCPRNCHG 
       360        370        380        390        400
NGECVSGVCH CFPGFLGADC AKAACPVLCS GNGQYSKGTC QCYSGWKGAE 
       410        420        430        440        450
CDVPMNQCID PSCGGHGSCI DGNCVCSAGY KGEHCEEVDC LDPTCSSHGV 
       460        470        480        490        500
CVNGECLCSP GWGGLNCELA RVQCPDQCSG HGTYLPDTGL CSCDPNWMGP 
       510        520        530        540        550
DCSVEVCSVD CGTHGVCIGG ACRCEEGWTG AACDQRVCHP RCIEHGTCKD 
       560        570        580        590        600
GKCECREGWN GEHCTIGRQT AGTETDGCPD LCNGNGRCTL GQNSWQCVCQ 
       610        620        630        640        650
TGWRGPGCNV AMETSCADNK DNEGDGLVDC LDPDCCLQSA CQNSLLCRGS 
       660        670        680        690        700
RDPLDIIQQG QTDWPAVKSF YDRIKLLAGK DSTHIIPGEN PFNSSLVSLI 
       710        720        730        740        750
RGQVVTTDGT PLVGVNVSFV KYPKYGYTIT RQDGTFDLIA NGGASLTLHF 
       760        770        780        790        800
ERAPFMSQER TVWLPWNSFY AMDTLVMKTE ENSIPSCDLS GFVRPDPIII 
       810        820        830        840        850
SSPLSTFFSA APGQNPIVPE TQVLHEEIEL PGSNVKLRYL SSRTAGYKSL 
       860        870        880        890        900
LKITMTQSTV PLNLIRVHLM VAVEGHLFQK SFQASPNLAY TFIWDKTDAY 
       910        920        930        940        950
GQRVYGLSDA VVSVGFEYET CPSLILWEKR TALLQGFELD PSNLGGWSLD 
       960        970        980        990       1000
KHHILNVKSG ILHKGTGENQ FLTQQPAIIT SIMGNGRRRS ISCPSCNGLA 
      1010       1020       1030       1040       1050
EGNKLLAPVA LAVGIDGSLY VGDFNYIRRI FPSRNVTSIL ELRNNPAHKY 
      1060       1070       1080       1090       1100
YLAVDPVSGS LYVSDTNSRR IYRVKSLSGT KDLAGNSEVV AGTGEQCLPF 
      1110       1120       1130       1140       1150
DEARCGDGGK AIDATLMSPR GIAVDKNGLM YFVDATMIRK VDQNGIISTL 
      1160       1170       1180       1190       1200
LGSNDLTAVR PLSCDSSMDV AQVRLEWPTD LAVNPMDNSL YVLENNVILR 
      1210       1220       1230       1240       1250
ITENHQVSII AGRPMHCQVP GIDYSLSKLA IHSALESASA IAISHTGVLY 
      1260       1270       1280       1290       1300
ITETDEKKIN RLRQVTTNGE ICLLAGAASD CDCKNDVNCN CYSGDDAYAT 
      1310       1320       1330       1340       1350
DAILNSPSSL AVAPDGTIYI ADLGNIRIRA VSKNKPVLNA FNQYEAASPG 
      1360       1370       1380       1390       1400
EQELYVFNAD GIHQYTVSLV TGEYLYNFTY STDNDVTELI DNNGNSLKIR 
      1410       1420       1430       1440       1450
RDSSGMPRHL LMPDNQIITL TVGTNGGLKV VSTQNLELGL MTYDGNTGLL 
      1460       1470       1480       1490       1500
ATKSDETGWT TFYDYDHEGR LTNVTRPTGV VTSLHREMEK SITIDIENSN 
      1510       1520       1530       1540       1550
RDDDVTVITN LSSVEASYTV VQDQVRNSYQ LCNNGTLRVM YANGMGISFH 
      1560       1570       1580       1590       1600
SEPHVLAGTI TPTIGRCNIS LPMENGLNSI EWRLRKEQIK GKVTIFGRKL 
      1610       1620       1630       1640       1650
RVHGRNLLSI DYDRNIRTEK IYDDHRKFTL RIIYDQVGRP FLWLPSSGLA 
      1660       1670       1680       1690       1700
AVNVSYFFNG RLAGLQRGAM SERTDIDKQG RIVSRMFADG KVWSYSYLDK 
      1710       1720       1730       1740       1750
SMVLLLQSQR QYIFEYDSSD RLLAVTMPSV ARHSMSTHTS IGYIRNIYNP 
      1760       1770       1780       1790       1800
PESNASVIFD YSDDGRILKT SFLGTGRQVF YKYGKLSKLS EIVYDSTAVT 
      1810       1820       1830       1840       1850
FGYDETTGVL KMVNLQSGGF SCTIRYRKIG PLVDKQIYRF SEEGMVNARF 
      1860       1870       1880       1890       1900
DYTYHDNSFR IASIKPVISE TPLPVDLYRY DEISGKVEHF GKFGVIYYDI 
      1910       1920       1930       1940       1950
NQIITTAVMT LSKHFDTHGR IKEVQYEMFR SLMYWMTVQY DSMGRVIKRE 
      1960       1970       1980       1990       2000
LKLGPYANTT KYTYDYDGDG QLQSVAVNDR PTWRYSYDLN GNLHLLNPGN 
      2010       2020       2030       2040       2050
SVRLMPLRYD LRDRITRLGD VQYKIDDDGY LCQRGSDIFE YNSKGLLTRA 
      2060       2070       2080       2090       2100
YNKASGWSVQ YRYDGVGRRA SYKTNLGHHL QYFYSDLHNP TRITHVYNHS 
      2110       2120       2130       2140       2150
NSEITSLYYD LQGHLFAMES SSGEEYYVAS DNTGTPLAVF SINGLMIKQL 
      2160       2170       2180       2190       2200
QYTAYGEIYY DSNPDFQMVI GFHGGLYDPL TKLVHFTQRD YDVLAGRWTS 
      2210       2220       2230       2240       2250
PDYTMWKNVG KEPAPFNLYM FKSNNPLSSE LDLKNYVTDV KSWLVMFGFQ 
      2260       2270       2280       2290       2300
LSNIIPGFPR AKMYFVPPPY ELSESQASEN GQLITGVQQT TERHNQAFMA 
      2310       2320       2330       2340       2350
LEGQVITKKL HASIREKAGH WFATTTPIIG KGIMFAIKEG RVTTGVSSIA 
      2360       2370       2380       2390       2400
SEDSRKVASV LNNAYYLDKM HYSIEGKDTH YFVKIGSADG DLVTLGTTIG 
      2410       2420       2430       2440       2450
RKVLESGVNV TVSQPTLLVN GRTRRFTNIE FQYSTLLLSI RYGLTPDTLD 
      2460       2470       2480       2490       2500
EEKARVLDQA RQRALGTAWA KEQQKARDGR EGSRLWTEGE KQQLLSTGRV 
      2510       2520       2530 
QGYEGYYVLP VEQYPELADS SSNIQFLRQN EMGKR
Length:2,535
Mass (Da):281,521
Last modified:September 21, 2011 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i01A32B84E965605D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q9NT68TEN2_HUMAN
Teneurin-2
TENM2 KIAA1127, ODZ2, TNM2
2,774Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
G3V106G3V106_HUMAN
HCG38403, isoform CRA_b
TENM2 hCG_38403
2,653Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC008601 Genomic DNA No translation available.
AC008634 Genomic DNA No translation available.
AC008642 Genomic DNA No translation available.
AC008708 Genomic DNA No translation available.
AC011384 Genomic DNA No translation available.
AC091820 Genomic DNA No translation available.
AC093304 Genomic DNA No translation available.
AC113372 Genomic DNA No translation available.
KC877165 Genomic DNA No translation available.

NCBI Reference Sequences

More...RefSeqi		NP_001073897.2, NM_001080428.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000520394; ENSP00000427874; ENSG00000145934

Database of genes from NCBI RefSeq genomes

More...GeneIDi		57451

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:57451

UCSC genome browser

More...UCSCi		uc003lzr.6, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC008601 Genomic DNA No translation available.
AC008634 Genomic DNA No translation available.
AC008642 Genomic DNA No translation available.
AC008708 Genomic DNA No translation available.
AC011384 Genomic DNA No translation available.
AC091820 Genomic DNA No translation available.
AC093304 Genomic DNA No translation available.
AC113372 Genomic DNA No translation available.
KC877165 Genomic DNA No translation available.
RefSeqiNP_001073897.2, NM_001080428.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

MaxQBiF8VNQ3
PeptideAtlasiF8VNQ3
PRIDEiF8VNQ3
ProteomicsDBi28188

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		49097, 10 antibodies

Genome annotation databases

EnsembliENST00000520394; ENSP00000427874; ENSG00000145934
GeneIDi57451
KEGGihsa:57451
UCSCiuc003lzr.6, human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		57451
EuPathDBiHostDB:ENSG00000145934.15
HGNCiHGNC:29943, TENM2
OpenTargetsiENSG00000145934

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

GeneTreeiENSGT01010000222317
HOGENOMiCLU_000229_0_0_1

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		57451, 1 hit in 109 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TENM2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		57451

Gene expression databases

BgeeiENSG00000145934, Expressed in left ventricle myocardium and 175 other tissues
ExpressionAtlasiF8VNQ3, baseline and differential

Family and domain databases

Gene3Di2.120.10.30, 2 hits
InterProiView protein in InterPro
IPR011042, 6-blade_b-propeller_TolB-like
IPR008969, CarboxyPept-like_regulatory
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR011044, Quino_amine_DH_bsu
IPR022385, Rhs_assc_core
IPR027689, Ten-2/3
IPR009471, Ten_N
IPR028916, Tox-GHH_dom
IPR006530, YD
PANTHERiPTHR11219:SF8, PTHR11219:SF8, 2 hits
PfamiView protein in Pfam
PF06484, Ten_N, 1 hit
PF15636, Tox-GHH, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 8 hits
SM00179, EGF_CA, 2 hits
SUPFAMiSSF49464, SSF49464, 1 hit
SSF50969, SSF50969, 1 hit
TIGRFAMsiTIGR03696, Rhs_assc_core, 1 hit
TIGR01643, YD_repeat_2x, 1 hit
PROSITEiView protein in PROSITE
PS00022, EGF_1, 6 hits
PS01186, EGF_2, 5 hits
PS50026, EGF_3, 5 hits
PS51361, TENEURIN_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF8VNQ3_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F8VNQ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: December 2, 2020
This is version 80 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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