UniProtKB - F8SLQ1 (F8SLQ1_MOUSE)
Protein
Submitted name:
PEX5-related protein
Gene
Pex5l
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- peroxisome targeting sequence binding Source: Ensembl
- small GTPase binding Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: PEX5-related proteinImportedSubmitted name: Peroxisomal biogenesis factor 5-like protein transcript variant 6ImportedSubmitted name: Peroxisomal biogenesis factor 5-like protein transcript variant 7ImportedSubmitted name: Peroxisomal biogenesis factor 5-like protein transcript variant 8Imported |
Gene namesi | Name:Pex5lImported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1916672, Pex5l |
Subcellular locationi
Other locations
- Cytoplasm ARBA annotation
- Membrane ARBA annotation; Peripheral membrane protein ARBA annotation
Other locations
- cytoplasm Source: UniProtKB-SubCell
- membrane Source: UniProtKB-SubCell
- receptor complex Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000027674, Expressed in retinal neural layer and 152 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 350 – 599 | TPR_REGIONInterPro annotationAdd BLAST | 250 | |
Repeati | 384 – 417 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 418 – 451 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 498 – 531 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 532 – 565 | TPRPROSITE-ProRule annotationAdd BLAST | 34 | |
Repeati | 566 – 599 | TPRPROSITE-ProRule annotationAdd BLAST | 34 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 142 – 176 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 233 – 252 | DisorderedSequence analysisAdd BLAST | 20 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 155 – 171 | PolyampholyteSequence analysisAdd BLAST | 17 |
Sequence similaritiesi
Belongs to the peroxisomal targeting signal receptor family.ARBA annotation
Keywords - Domaini
TPR repeatPROSITE-ProRule annotationPhylogenomic databases
GeneTreei | ENSGT00940000155931 |
OrthoDBi | 588648at2759 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR024112, PEX5-rel IPR024111, PTS1R_family IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
PANTHERi | PTHR10130, PTHR10130, 1 hit PTHR10130:SF1, PTHR10130:SF1, 1 hit |
Pfami | View protein in Pfam PF13181, TPR_8, 2 hits |
SMARTi | View protein in SMART SM00028, TPR, 5 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50005, TPR, 5 hits PS50293, TPR_REGION, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F8SLQ1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDSEMDGRT HIPSLLNALL SRNRVMQMSY LKSKEQGYGK LSSDEDLEII
60 70 80 90 100
VDQKQGKGSR AADKAVAMVM KEIPREESAE EKPLLTVTSQ LVNEQQESRP
110 120 130 140 150
LLSPSIDDFL CETKSEAIAK PVTSNTAVLT TGLDLLDLSE PVSQTQTKAK
160 170 180 190 200
KSEPSSKSSS LKKKADGSDL ISADAEQRAQ ALRGPETSSL DLDIQTQLEK
210 220 230 240 250
WDDVKFHGDR TSKGHLMAER KSCSSRTGSK ELLWSAEHRS QPELSTGKSA
260 270 280 290 300
LNSESASELE LVAPAQARLT KEHRWGSALL SRNHSLEEEF ERAKAAVESD
310 320 330 340 350
TEFWDKMQAE WEEMARRNWI SENQEAQNQV TVSASEKGYY FHTENPFKDW
360 370 380 390 400
PGAFEEGLKR LKEGDLPVTI LFMEAAILQD PGDAEAWQFL GITQAENENE
410 420 430 440 450
QAAIVALQRC LELQPNNLKA LMALAVSYTN TSHQQDACEA LKNWIKQNPK
460 470 480 490 500
YKYLVKNKKG SPGLTRRMSK SPVDSSVLEG VKELYLEAAH QNGDMIDPDL
510 520 530 540 550
QTGLGVLFHL SGEFNRAIDA FNAALTVRPE DYSLWNRLGA TLANGDRSEE
560 570 580 590 600
AVEAYTRALE IQPGFIRSRY NLGISCINLG AYREAVSNFL TALSLQRKSR
610 620 630 640 650
NQQQVPHPAI SGNIWAALRI ALSLMDQPEL FQAANLGDLD VLLRAFNLDP
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ8C437 | PEX5R_MOUSE | PEX5-related protein | Pex5l Pex2, Pex5r, Pxr2 | 567 | Annotation score: | ||
F8SLP9 | F8SLP9_MOUSE | PEX5-related protein | Pex5l | 567 | Annotation score: | ||
D3YYH0 | D3YYH0_MOUSE | PEX5-related protein | Pex5l | 591 | Annotation score: | ||
F8SLQ3 | F8SLQ3_MOUSE | PEX5-related protein | Pex5l | 615 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC116723 Genomic DNA No translation available. AC119877 Genomic DNA No translation available. HQ646191 mRNA Translation: AEH94556.1 HQ646192 mRNA Translation: AEH94557.1 HQ646193 mRNA Translation: AEH94558.1 |
RefSeqi | NP_001156988.1, NM_001163516.3 NP_001156989.1, NM_001163517.3 NP_001276434.1, NM_001289505.2 NP_001297389.1, NM_001310460.1 NP_067458.2, NM_021483.5 XP_011247994.1, XM_011249692.2 |
Genome annotation databases
Ensembli | ENSMUST00000193289; ENSMUSP00000142008; ENSMUSG00000027674 ENSMUST00000193681; ENSMUSP00000141454; ENSMUSG00000027674 ENSMUST00000194016; ENSMUSP00000142196; ENSMUSG00000027674 |
GeneIDi | 58869 |
KEGGi | mmu:58869 |
UCSCi | uc029uko.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC116723 Genomic DNA No translation available. AC119877 Genomic DNA No translation available. HQ646191 mRNA Translation: AEH94556.1 HQ646192 mRNA Translation: AEH94557.1 HQ646193 mRNA Translation: AEH94558.1 |
RefSeqi | NP_001156988.1, NM_001163516.3 NP_001156989.1, NM_001163517.3 NP_001276434.1, NM_001289505.2 NP_001297389.1, NM_001310460.1 NP_067458.2, NM_021483.5 XP_011247994.1, XM_011249692.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 54548, 43 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000193289; ENSMUSP00000142008; ENSMUSG00000027674 ENSMUST00000193681; ENSMUSP00000141454; ENSMUSG00000027674 ENSMUST00000194016; ENSMUSP00000142196; ENSMUSG00000027674 |
GeneIDi | 58869 |
KEGGi | mmu:58869 |
UCSCi | uc029uko.2, mouse |
Organism-specific databases
CTDi | 51555 |
MGIi | MGI:1916672, Pex5l |
Phylogenomic databases
GeneTreei | ENSGT00940000155931 |
OrthoDBi | 588648at2759 |
Miscellaneous databases
BioGRID-ORCSi | 58869, 0 hits in 17 CRISPR screens |
ChiTaRSi | Pex5l, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000027674, Expressed in retinal neural layer and 152 other tissues |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR024112, PEX5-rel IPR024111, PTS1R_family IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR019734, TPR_repeat |
PANTHERi | PTHR10130, PTHR10130, 1 hit PTHR10130:SF1, PTHR10130:SF1, 1 hit |
Pfami | View protein in Pfam PF13181, TPR_8, 2 hits |
SMARTi | View protein in SMART SM00028, TPR, 5 hits |
SUPFAMi | SSF48452, SSF48452, 1 hit |
PROSITEi | View protein in PROSITE PS50005, TPR, 5 hits PS50293, TPR_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F8SLQ1_MOUSE | |
Accessioni | F8SLQ1Primary (citable) accession number: F8SLQ1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 21, 2011 |
Last sequence update: | September 21, 2011 | |
Last modified: | December 2, 2020 | |
This is version 66 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |