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Protein

Chromosomal replication initiator protein DnaA

Gene

dnaA

Organism
Prevotella multisaccharivorax DSM 17128
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.UniRule annotationSAAS annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi195 – 202ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation
Biological processDNA replicationUniRule annotationSAAS annotation
LigandATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Chromosomal replication initiator protein DnaAUniRule annotationSAAS annotation
Gene namesi
Name:dnaAUniRule annotation
ORF Names:Premu_1989Imported
OrganismiPrevotella multisaccharivorax DSM 17128Imported
Taxonomic identifieri688246 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidiaBacteroidalesPrevotellaceaePrevotella
Proteomesi
  • UP000002772 Componenti: Unassembled WGS sequence

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi688246.Premu_1989

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini187 – 319AAAInterPro annotationAdd BLAST133
Domaini398 – 467Bac_DnaA_CInterPro annotationAdd BLAST70

Sequence similaritiesi

Belongs to the DnaA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CI4 Bacteria
COG0593 LUCA
OrthoDBiPOG091H02FF

Family and domain databases

CDDicd06571 Bac_DnaA_C, 1 hit
Gene3Di1.10.1750.10, 1 hit
3.30.300.180, 1 hit
HAMAPiMF_00377 DnaA_bact, 1 hit
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR001957 Chromosome_initiator_DnaA
IPR020591 Chromosome_initiator_DnaA-like
IPR018312 Chromosome_initiator_DnaA_CS
IPR013317 DnaA
IPR013159 DnaA_C
IPR024633 DnaA_N_dom
IPR038454 DnaA_N_sf
IPR027417 P-loop_NTPase
IPR010921 Trp_repressor/repl_initiator
PANTHERiPTHR30050:SF2 PTHR30050:SF2, 1 hit
PfamiView protein in Pfam
PF00308 Bac_DnaA, 1 hit
PF08299 Bac_DnaA_C, 1 hit
PF11638 DnaA_N, 1 hit
PRINTSiPR00051 DNAA
SMARTiView protein in SMART
SM00382 AAA, 1 hit
SM00760 Bac_DnaA_C, 1 hit
SUPFAMiSSF48295 SSF48295, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00362 DnaA, 1 hit
PROSITEiView protein in PROSITE
PS01008 DNAA, 1 hit

Sequencei

Sequence statusi: Complete.

F8N771-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPFHEKGQDD RGQSTSTKLN EMKAKEDSRW LKALTLIRQN VTGQIYDTWF
60 70 80 90 100
KPIVFEHFDE AQRMILVQVP SPFVYEYLEE NFVDLLTKVL YECFGPKIHL
110 120 130 140 150
SYRVVVDKEG KDSGGTETVW SEPANGVKQQ PLQRGNQSPT PLDAAQPQAL
160 170 180 190 200
DPQLNPHLTF ANYIEGDSNK LPRSVGQSIA EHPGTMQFNP MFIYGPSGCG
210 220 230 240 250
KTHLINAIGM RTKELYPQKR VLYISARLFQ VQYSNAVLQN TVNSFIAFYQ
260 270 280 290 300
TIDMLIVDDI QEWMGKTGTL NTFFHIFNNL FRNGKRIILA SDRPPVDLKD
310 320 330 340 350
MPDRLLTRFS CGLIAELEKP NRKLCVDILE NKIKRDGLKI PRDVIEFIAE
360 370 380 390 400
TASGSVRDLE GVIQSLLAYC IVYNCNIDMR LAQRVIKRAV KVDDRPLTVD
410 420 430 440 450
DILEKVCRHY NVTTTQINSK SRKRDYVVAR QVSMYLAQKY TKMPASRIGK
460 470 480 490
LVGNRDHSTV IHSCSQVEKR IQVDEAFSAE LVSIETSFKL KKQ
Length:493
Mass (Da):56,320
Last modified:September 21, 2011 - v1
Checksum:i6A5499E7A9EDAA1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GL945017 Genomic DNA Translation: EGN57387.1

Genome annotation databases

EnsemblBacteriaiEGN57387; EGN57387; Premu_1989

Similar proteinsi

Entry informationi

Entry nameiF8N771_9BACT
AccessioniPrimary (citable) accession number: F8N771
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: June 20, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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