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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Streptococcus thermophilus JIM 8232
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei138UniRule annotation1
Active sitei603UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotationImported
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotationImported
ORF Names:STH8232_0911Imported
OrganismiStreptococcus thermophilus JIM 8232Imported
Taxonomic identifieri1051074 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000000300 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliF8LWI1
SMRiF8LWI1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

KOiK01595

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

F8LWI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFNKLESSN NQEIISEEVG ILKELLDDAT RGIAGEQGLT TIQHLVELYD
60 70 80 90 100
EGDYEALTQA ISEMTNDDMV VASRYFSLLP LLINISEDVD LAYEVNRKNN
110 120 130 140 150
IDESYLGKLS ETFDVVAESD NARDILENVN VVPVLTAHPT QVQRKTMLEL
160 170 180 190 200
TNHIHELLRK HRDVKDGLIN KDKWYADLRR YVEIMMKTDI IREKKLKVKN
210 220 230 240 250
EITNVMEYYN SSLIKAITKL SHEFKRLAVE KGIELDNPTP ITMGMWIGGD
260 270 280 290 300
RDGNPFVTAE TLKLSATLQS EVILNYYIEK VDNLYRSFSL SSRLTEVSET
310 320 330 340 350
VAEMAKLSPD TSVYRENEPY RRAFSYIQSK LIQTLLFFKA GNFSNERAAK
360 370 380 390 400
RLSENVRLGS VSTGEVVADF VHDRLSQSLQ AVSQQTTEFY ETAEAFHDDL
410 420 430 440 450
LAIKNSLLEN DDSVLISGDF EELLQAVEVF GFYLATIDMR QDSSVHEACV
460 470 480 490 500
AELLKSANIV DNYSELTEVE KVAVLLKELQ EDPRTLSSTN VSKSETLEKE
510 520 530 540 550
LAIFRTARLL KDYLGEEVIK QHIISHTESV SDMFELAILL KEVGLVDTER
560 570 580 590 600
ARVQIVPLFE TIEDLENSNE IMKQYLGYDI VKRWIKNSNN YQEIMLGYSD
610 620 630 640 650
SNKDGGYLSS GWTLYKAQNE LTKIGEERGI KITFFHGRGG TVGRGGGPSY
660 670 680 690 700
DAITSQPFGT IKDRIRLTEQ GEVIGNKYGN KDAAYYNLEM LVSATLDRMV
710 720 730 740 750
TRQITDPDEL VDFREIMDSI VQDSNGIYRD LVFGNEHFYD YFFEASPIKE
760 770 780 790 800
VSSLNIGSRP AARKTITDIS GLRAIPWVFS WSQNRIMLPG WYGVGSAFNH
810 820 830 840 850
YIEAEEGNLE KLQHMFETWP FFRSLLSNVD MVLSKSDMNI AFHYAQLAES
860 870 880 890 900
EEVRSVFNII LDEWQLTKNV ILAIEKHDDF LEESPSLKAS LGFRLPYFNV
910 920 930 940
LNYIQIELIK RLRNNNLTDD EISLIHITIN GIATGLRNSG
Length:940
Mass (Da):107,012
Last modified:September 21, 2011 - v1
Checksum:i369DE223D6E0E59A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR875178 Genomic DNA Translation: CCC19618.1
RefSeqiWP_011680994.1, NC_017581.1

Genome annotation databases

EnsemblBacteriaiCCC19618; CCC19618; STH8232_0911
GeneIDi31937564
KEGGistu:STH8232_0911
PATRICifig|1051074.3.peg.775

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR875178 Genomic DNA Translation: CCC19618.1
RefSeqiWP_011680994.1, NC_017581.1

3D structure databases

ProteinModelPortaliF8LWI1
SMRiF8LWI1
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCCC19618; CCC19618; STH8232_0911
GeneIDi31937564
KEGGistu:STH8232_0911
PATRICifig|1051074.3.peg.775

Phylogenomic databases

KOiK01595

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8LWI1_STRTR
AccessioniPrimary (citable) accession number: F8LWI1
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: November 7, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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