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Protein
Submitted name:

LIM domain only 7 protein

Gene

LMO7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
LIM domain only 7 proteinImported
Gene namesi
Name:LMO7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiF8J2B5
PRIDEiF8J2B5

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 129Calponin-homology (CH)InterPro annotationAdd BLAST118
Domaini990 – 1066PDZInterPro annotationAdd BLAST77
Domaini1560 – 1626LIM zinc-bindingInterPro annotationAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili669 – 724Sequence analysisAdd BLAST56
Coiled coili1175 – 1225Sequence analysisAdd BLAST51
Coiled coili1295 – 1332Sequence analysisAdd BLAST38

Keywords - Domaini

Coiled coilSequence analysis, LIM domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1704 Eukaryota
ENOG410XP0W LUCA
KOiK06084

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR031865 DUF4757
IPR029978 LMO-7
IPR001478 PDZ
IPR036034 PDZ_sf
IPR003096 SM22_calponin
IPR001781 Znf_LIM
PANTHERiPTHR15551:SF4 PTHR15551:SF4, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
PF15949 DUF4757, 2 hits
PF00412 LIM, 1 hit
PF00595 PDZ, 1 hit
PRINTSiPR00888 SM22CALPONIN
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00132 LIM, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
SSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS00478 LIM_DOMAIN_1, 1 hit
PS50023 LIM_DOMAIN_2, 1 hit
PS50106 PDZ, 1 hit

Sequencei

Sequence statusi: Complete.

F8J2B5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEGLEEAEAN CSVAFAEAQR WVEAVTEKNF ETKDFRASLE NGVLLCDLIN
60 70 80 90 100
KLKPGVIKKI NRLSTPIAGL DNINVFLKAC EQIGLKEAQL FHPGDLQDLS
110 120 130 140 150
NRVTVKQEET DRRVKNVLIT LYWLGRKAQS NPYYNGPHLN LKAFENLLGQ
160 170 180 190 200
ALTKALEDSS FLKRSGRDSG YGDIWCPERG EFLAPPRHHK REDSFESLDS
210 220 230 240 250
LGSRSLTSCS SDITLRGGRE GFESDTDSEF TFKMQDYNKD DMSYRRISAV
260 270 280 290 300
EPKTALPFNR FLPNKSRQPS YVPAPLRKKK PDKHEDNRRS WASPVYTEAD
310 320 330 340 350
GTFSSNQRRI WGTNVENWPT VQGTSKSSCY LEEEKAKTRS IPNIVKDDLY
360 370 380 390 400
VRKLSPVMPN PGNAFDQFLP KCWTPEDVNW KRIKRETYKP WYKEFQGFSQ
410 420 430 440 450
FLLLQALQTY SDDILSSETH TKIDPTSGPR LITRRKNLSY APGYRRDDLE
460 470 480 490 500
MAALDPDLEN DDFFVRKTGV FHANPYVLRA FEDFRKFSEQ DDSVERDIIL
510 520 530 540 550
QCREGELVLP DLEKDDMIVR RIPAQKKEVP LSGAPDRYHP VPFPEPWTLP
560 570 580 590 600
PEIQAKFLCV FERTCPSKEK SNSCRILVPS YRQKKDDMLT RKIQSWKLGT
610 620 630 640 650
TVPPISFTPG PCSEADLKRW EAIREASRLR HKKRLMVERL FQKIYGENGS
660 670 680 690 700
KSMSDVSAED VQNLRQLRYE EMQKIKSQLK EQDQKWQDDL AKWKDRRKSY
710 720 730 740 750
TSDLQKKKEE REEIEKQALE KSKRSSKTFK EMLQDRESQN QKSTVPSRRR
760 770 780 790 800
MYSFDDVLEE GKRPPTMTVS EASYQSERVE EKGATYPSEI PKEDSTTFAK
810 820 830 840 850
REDRVTTEIQ LPSQSPVEEQ SPASLSSLRS RSTQMESTRV SASLPRSYRK
860 870 880 890 900
TDTVRLTSVV TPRPFGSQTR GISSLPRSYT MDDAWKYNGD VEDIKRTPNN
910 920 930 940 950
VVSTPAPSPD ASQLASSLSS QKEVAATEED VTRLPSPTSP FSSLSQDQAA
960 970 980 990 1000
TSKATLSSTS GLDLMSESGE GEISPQREVS RSQDQFSDMR ISINQTPGKS
1010 1020 1030 1040 1050
LDFGFTIKWD IPGIFVASVE AGSPAEFSQL QVDDEIIAIN NTKFSYNDSK
1060 1070 1080 1090 1100
EWEEAMAKAQ ETGHLVMDVR RYGKAGSPET KWIDATSGIY NSEKSSNLSV
1110 1120 1130 1140 1150
TTDFSESLQS SNIESKEING IHDESNAFES KASESISLKN LKRRSQFFEQ
1160 1170 1180 1190 1200
GSSDSVVPDL PVPTISAPSR WVWDQEEERK RQERWQKEQD RLLQEKYQRE
1210 1220 1230 1240 1250
QEKLREEWQR AKQEAERENS KYLDEELMVL SSNSMSLTTR EPSLATWEAT
1260 1270 1280 1290 1300
WSEGSKSSDR EGTRAGEEER RQPQEEVVHE DQGKKPQDQL VIERERKWEQ
1310 1320 1330 1340 1350
QLQEEQEQKR LQAEAEEQKR PAEEQKRQAE IERETSVRIY QYRRPVDSYD
1360 1370 1380 1390 1400
IPKTEEASSG FLPGDRNKSR STTELDDYST NKNGNNKYLD QIGNMTSSQR
1410 1420 1430 1440 1450
RSKKEQVPSG AELERQQILQ EMRKRTPLHN DNSWIRQRSA SVNKEPVSLP
1460 1470 1480 1490 1500
GIMRRGESLD NLDSPRSNSW RQPPWLNQPT GFYASSSVQD FSRPPPQLVS
1510 1520 1530 1540 1550
TSNRAYMRNP SSSVPPPSAG SVKTSTTGVA TTQSPTPRSH SPSASQSGSQ
1560 1570 1580 1590 1600
LRNRSVSGKR ICSYCNNILG KGAAMIIESL GLCYHLHCFK CVACECDLGG
1610 1620 1630
SSSGAEVRIR NHQLYCNDCY LRFKSGRPTA M
Length:1,631
Mass (Da):186,241
Last modified:September 21, 2011 - v1
Checksum:i5FC1483913806856
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ711162 mRNA Translation: ACV60543.1
RefSeqiNP_001293009.1, NM_001306080.1
NP_001317512.1, NM_001330583.1
UniGeneiHs.207631

Genome annotation databases

GeneIDi4008
KEGGihsa:4008

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FJ711162 mRNA Translation: ACV60543.1
RefSeqiNP_001293009.1, NM_001306080.1
NP_001317512.1, NM_001330583.1
UniGeneiHs.207631

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiF8J2B5
PRIDEiF8J2B5

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4008
KEGGihsa:4008

Organism-specific databases

CTDi4008

Phylogenomic databases

eggNOGiKOG1704 Eukaryota
ENOG410XP0W LUCA
KOiK06084

Miscellaneous databases

ChiTaRSiLMO7 human
GenomeRNAii4008

Family and domain databases

CDDicd00014 CH, 1 hit
Gene3Di1.10.418.10, 1 hit
InterProiView protein in InterPro
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR031865 DUF4757
IPR029978 LMO-7
IPR001478 PDZ
IPR036034 PDZ_sf
IPR003096 SM22_calponin
IPR001781 Znf_LIM
PANTHERiPTHR15551:SF4 PTHR15551:SF4, 1 hit
PfamiView protein in Pfam
PF00307 CH, 1 hit
PF15949 DUF4757, 2 hits
PF00412 LIM, 1 hit
PF00595 PDZ, 1 hit
PRINTSiPR00888 SM22CALPONIN
SMARTiView protein in SMART
SM00033 CH, 1 hit
SM00132 LIM, 1 hit
SM00228 PDZ, 1 hit
SUPFAMiSSF47576 SSF47576, 1 hit
SSF50156 SSF50156, 1 hit
PROSITEiView protein in PROSITE
PS50021 CH, 1 hit
PS00478 LIM_DOMAIN_1, 1 hit
PS50023 LIM_DOMAIN_2, 1 hit
PS50106 PDZ, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF8J2B5_HUMAN
AccessioniPrimary (citable) accession number: F8J2B5
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: May 23, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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