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Protein

Thymidine kinase

Gene

tdk

Organism
Vibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei104Proton acceptorUniRule annotation1
Metal bindingi161ZincUniRule annotation1
Metal bindingi163ZincUniRule annotation1
Metal bindingi198ZincUniRule annotation1
Metal bindingi201ZincUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi25 – 32ATPUniRule annotation8
Nucleotide bindingi103 – 106ATPUniRule annotation4

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Metal-bindingUniRule annotation, Nucleotide-binding, ZincUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Name:tdkUniRule annotation
Ordered Locus Names:VAA_02154Imported
OrganismiVibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum)Imported
Taxonomic identifieri882102 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000006800 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi882102.VAA_02154

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107104 Bacteria
COG1435 LUCA
KOiK00857
OMAiKEQFGWI
OrthoDBiPOG091H0659

Family and domain databases

HAMAPiMF_00124 Thymidine_kinase, 1 hit
InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 1 hit
PfamiView protein in Pfam
PF00265 TK, 1 hit
PIRSFiPIRSF035805 TK_cell, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

F7YKS3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLVLSPIDL VTGISLLAQM YFYYSAMNAG KSTTLLQSSF NYQERGMTPV
60 70 80 90 100
IYTAAIDDRY GVGKVSSRIG LESDAQLFTA ETNLYDEINA LHEQQKRHCI
110 120 130 140 150
LVDECQFLTK DQVYQLTEVV DKIGIPVLCY GLRTDFLGEL FEGSKYLLSW
160 170 180 190 200
ADKLVELKTI CHCGRKANMV IRTDEHGVAI AEGDQVSIGG NDKYVSVCRQ

HYKEALGK
Length:208
Mass (Da):23,310
Last modified:September 21, 2011 - v1
Checksum:i51CAA723309640DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002284 Genomic DNA Translation: AEH33418.1

Genome annotation databases

EnsemblBacteriaiAEH33418; AEH33418; VAA_02154
KEGGivan:VAA_02154

Similar proteinsi

Entry informationi

Entry nameiF7YKS3_VIBA7
AccessioniPrimary (citable) accession number: F7YKS3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 21, 2011
Last sequence update: September 21, 2011
Last modified: March 28, 2018
This is version 38 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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