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Protein

Erythropoietin receptor

Gene

EPOR

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Receptor for erythropoietin.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Erythropoietin receptorUniRule annotation
Short name:
EPO-RUniRule annotation
Gene namesi
Name:EPORImported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondUniRule annotation

Interactioni

Subunit structurei

Forms homodimers on EPO stimulation.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000010477

Family & Domainsi

Sequence similaritiesi

Belongs to the type I cytokine receptor family. Type 1 subfamily.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IFGH Eukaryota
ENOG4111PGS LUCA
GeneTreeiENSGT00920000149107
InParanoidiF7ISG7
KOiK05079
OMAiVGSEHAQ
OrthoDBiEOG091G0AK8
TreeFamiTF336573

Family and domain databases

CDDicd00063 FN3, 1 hit
Gene3Di2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR009167 Erythropoietin_rcpt
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR015152 Growth/epo_recpt_lig-bind
IPR013783 Ig-like_fold
IPR003528 Long_hematopoietin_rcpt_CS
PANTHERiPTHR23037:SF28 PTHR23037:SF28, 1 hit
PfamiView protein in Pfam
PF09067 EpoR_lig-bind, 1 hit
PIRSFiPIRSF001959 EPO_receptor, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SUPFAMiSSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit
PS01352 HEMATOPO_REC_L_F1, 1 hit

Sequencei

Sequence statusi: Complete.

F7ISG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGHLVVSLWP QFGSLCLLLA GAACASPPNL PDSKFENKAA LLAARGSEEF
60 70 80 90 100
LCFTERLEDL VCFWEEAASA GMGPDNYSFS YQLDNEPWKR CRLHQAPTAR
110 120 130 140 150
GTVRFWCSLP RADTSSFVPL ELRVTVASSG ALRYHRIIHV NEVVLLDAPV
160 170 180 190 200
ELAARLADEG GHVVLRWLPP PGAPMPYHIR YEVDVSAGSG AGSTQRVEIL
210 220 230 240 250
EGRTECVLSN LRRLTRYTFA VRARMAEPSF GGFWSAWSKP VSLLTPTDLD
260 270 280 290 300
PLILTLSVIL VLILVLLTVL ALLSHRRALK QKIWPGIPSP ESEFEGLFTT
310 320 330 340 350
HKGNFQLWLY QNDGCLWWSP CTPFTEDPPV SLEVLSERCW GTMQPVEPGT
360 370 380 390 400
DDEGPQLEPV GSEHAQDTYL VLDKWLLPQS PPSEDLPRPD SSMDIVAMDE
410 420 430 440 450
GSEASSCTSA LALKPSPEGA SAASFEYTIL DPSSQLLRPW ELCPELPPTP
460 470 480 490 500
PHLKYLYLVV SDSGISTDYS SGDSQGAQGG SSDGPSSNPY ENSLIPASEP

LPPSYVTCS
Length:509
Mass (Da):55,681
Last modified:June 20, 2018 - v2
Checksum:i1DF9DA1F279104E4
GO

Genome annotation databases

EnsembliENSCJAT00000011073; ENSCJAP00000010477; ENSCJAG00000005704
KEGGicjc:100389634

Similar proteinsi

Entry informationi

Entry nameiF7ISG7_CALJA
AccessioniPrimary (citable) accession number: F7ISG7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: June 20, 2018
Last modified: July 18, 2018
This is version 41 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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