UniProtKB - F7IG69 (F7IG69_CALJA)
Protein
Nuclear receptor coactivator
Gene
NCOA1
Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Functioni
GO - Molecular functioni
- nuclear hormone receptor binding Source: UniProtKB-UniRule
- nuclear receptor transcription coactivator activity Source: InterPro
- protein dimerization activity Source: InterPro
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Molecular function | ActivatorUniRule annotationARBA annotation |
Biological process | Transcription, Transcription regulationUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Nuclear receptor coactivatorUniRule annotation |
Gene namesi | Name:NCOA1Imported |
Organismi | Callithrix jacchus (White-tufted-ear marmoset)Imported |
Taxonomic identifieri | 9483 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Platyrrhini › Cebidae › Callitrichinae › Callithrix › Callithrix |
Proteomesi |
|
Subcellular locationi
Keywords - Cellular componenti
NucleusUniRule annotationARBA annotationInteractioni
GO - Molecular functioni
- nuclear hormone receptor binding Source: UniProtKB-UniRule
- protein dimerization activity Source: InterPro
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 39 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 83 – 105 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 368 – 443 | DisorderedSequence analysisAdd BLAST | 76 | |
Regioni | 457 – 477 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 564 – 585 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 597 – 626 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 662 – 723 | DisorderedSequence analysisAdd BLAST | 62 | |
Regioni | 1146 – 1189 | DisorderedSequence analysisAdd BLAST | 44 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 373 – 443 | PolarSequence analysisAdd BLAST | 71 | |
Compositional biasi | 564 – 578 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 662 – 683 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 697 – 723 | PolarSequence analysisAdd BLAST | 27 | |
Compositional biasi | 1163 – 1177 | Pro-richSequence analysisAdd BLAST | 15 |
Sequence similaritiesi
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00950000183021 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit cd00130, PAS, 1 hit |
Gene3Di | 1.10.287.1070, 1 hit 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR010011, DUF1518 IPR036638, HLH_DNA-bd_sf IPR028819, NCOA1 IPR009110, Nuc_rcpt_coact IPR014920, Nuc_rcpt_coact_Ncoa-typ IPR037077, Nuc_rcpt_coact_Ncoa_int_sf IPR017426, Nuclear_rcpt_coactivator IPR000014, PAS IPR035965, PAS-like_dom_sf IPR013767, PAS_fold IPR014935, SRC/p160_LXXLL |
PANTHERi | PTHR10684, PTHR10684, 1 hit PTHR10684:SF1, PTHR10684:SF1, 1 hit |
Pfami | View protein in Pfam PF07469, DUF1518, 2 hits PF00010, HLH, 1 hit PF08815, Nuc_rec_co-act, 1 hit PF00989, PAS, 1 hit PF08832, SRC-1, 1 hit |
PIRSFi | PIRSF038181, Nuclear_receptor_coactivator, 2 hits |
SMARTi | View protein in SMART SM01151, DUF1518, 2 hits SM00353, HLH, 1 hit SM00091, PAS, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit SSF55785, SSF55785, 2 hits SSF69125, SSF69125, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit PS50112, PAS, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F7IG69-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGLGDSSSD PANPDSHKRK GSPCDTLASS TEKRRREQEN KYLEELAELL
60 70 80 90 100
SANISDIDSL SVKPDKCKIL KKTVDQIQLM KRMEQEKSTT DDDVQKSDIS
110 120 130 140 150
SSSQGVIEKE SLGPLLLEAL DGFFFVVNCE GRIVFVSENV TSYLGYNQEE
160 170 180 190 200
LMNTSVYSIL HVGDHAEFVK NLLPKSLVNG VPWPQEATRR NSHTFNCRML
210 220 230 240 250
IHPPDEPGTE NQEACQRYEV MQCFTVSQPK SIQEDGEDFQ SCLICIARRL
260 270 280 290 300
PRPPAITGVE SFMTKQDTTG KIISIDTSSL RAAGRTGWED LVRKCIYAFF
310 320 330 340 350
QPQGREPSYA RQLFQEVMTR GTASSPSYRF ILNDGTMLSA HTKCKLCYPQ
360 370 380 390 400
SPDMQPFIMG IHIIDREHSG LSPQDDTNSG MSIPRVNPSV NPNISPAHGV
410 420 430 440 450
ARSSTLPPSS SNMVSTRINR QQSSDLHSSS HSNSSNSQGS FGCSPGSQIV
460 470 480 490 500
ATVALNQGQA SSQSSNPSLN LNNSPMEGTG ISLAQFMSPR RQVTSGLATR
510 520 530 540 550
PRMPNNSFPP NISTLSSPVG MTSSACNNNN RSYSNIPVTS LQGMNEGPNN
560 570 580 590 600
SVGFSASSPV LRQISSQNSP NRLNIQPAKA ESKDNKEIAS ILNEMIQSDN
610 620 630 640 650
SSSDGKPLDS GLLHNSDRLS DGDSKYSQTS HKLVQLLTTT AEQQLRHADI
660 670 680 690 700
DTSCKDVLSC TGTSNSASAN SSGGSCPSSH SSLTERHKIL HRLLQEGSPS
710 720 730 740 750
DITTLSVEPD KKDSASTSVS VTGQVQGNSS IKLELDASKK KESKDHQLLR
760 770 780 790 800
YLLDKDEKDL RSTPNLSLDD VKVKVEKKEQ MDPCNTNPTP MTKPAPEEIK
810 820 830 840 850
LEAQSQFTAD LDQFDQLLPT LEKAAQLPGL CETDRMDGAV TSVTIKSEIL
860 870 880 890 900
PASLQSATAR PTSRLNRLPE LELEAIDNQF GQPGTGDQIP WTNNTVTAIN
910 920 930 940 950
QNKSEDQCIS SQLDELLCPP TTVEGRNDEK ALLEQLVSFL SGKDETELAE
960 970 980 990 1000
LDRALGIDKL VQGGGLDVLS ERFPPQQATP PLMMEERPSL YSQPYSSPSP
1010 1020 1030 1040 1050
TANLPSPFQG MVRQKPSLGT MPVQVTPPRG AFSPGMGMQP RQTLNRPPAA
1060 1070 1080 1090 1100
PNQLRLQLQQ RLQGQQQLIH QNRQAILNQF AATAPVGINM RSGMQQQITP
1110 1120 1130 1140 1150
QPPLNAQMLA QRQRELYSQQ HRQRQLIQQQ RAMLMRQQSF GNNLTPSSGL
1160 1170 1180 1190 1200
PVQMGNPRLP QGAPQQFPYP PNYGTNPGTP PASTSPFSQL AANPEASLAN
1210 1220 1230 1240 1250
RSSMVSRGMT GNMGGQFGTG INPQMQQNVF QYPGAGMVPQ GEANFAPSLS
1260 1270 1280 1290 1300
PGSSMVPMPI PPPQSSLLQQ TPPASGYQSP DMKAWQQGAI GNNNVFSQAV
1310 1320 1330 1340 1350
QNQPTPAQPG VYNNMSITVS MAGGNTNVQN MNPMMGQMQM SSLQMPGMNT
1360 1370 1380 1390
VCPEQISDPA LRHTGLYCNQ LSSTDLLKTE ADGTQDKKTE EFFSVVTTD
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketF7IG96 | F7IG96_CALJA | Nuclear receptor coactivator | NCOA1 | 1,441 | Annotation score: |
Sequence databases
RefSeqi | XP_008979304.1, XM_008981056.2 XP_017819999.1, XM_017964510.1 |
Genome annotation databases
Ensembli | ENSCJAT00000015508; ENSCJAP00000014700; ENSCJAG00000007912 |
GeneIDi | 100385756 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_008979304.1, XM_008981056.2 XP_017819999.1, XM_017964510.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSCJAT00000015508; ENSCJAP00000014700; ENSCJAG00000007912 |
GeneIDi | 100385756 |
Organism-specific databases
CTDi | 8648 |
Phylogenomic databases
GeneTreei | ENSGT00950000183021 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit cd00130, PAS, 1 hit |
Gene3Di | 1.10.287.1070, 1 hit 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR010011, DUF1518 IPR036638, HLH_DNA-bd_sf IPR028819, NCOA1 IPR009110, Nuc_rcpt_coact IPR014920, Nuc_rcpt_coact_Ncoa-typ IPR037077, Nuc_rcpt_coact_Ncoa_int_sf IPR017426, Nuclear_rcpt_coactivator IPR000014, PAS IPR035965, PAS-like_dom_sf IPR013767, PAS_fold IPR014935, SRC/p160_LXXLL |
PANTHERi | PTHR10684, PTHR10684, 1 hit PTHR10684:SF1, PTHR10684:SF1, 1 hit |
Pfami | View protein in Pfam PF07469, DUF1518, 2 hits PF00010, HLH, 1 hit PF08815, Nuc_rec_co-act, 1 hit PF00989, PAS, 1 hit PF08832, SRC-1, 1 hit |
PIRSFi | PIRSF038181, Nuclear_receptor_coactivator, 2 hits |
SMARTi | View protein in SMART SM01151, DUF1518, 2 hits SM00353, HLH, 1 hit SM00091, PAS, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit SSF55785, SSF55785, 2 hits SSF69125, SSF69125, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit PS50112, PAS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7IG69_CALJA | |
Accessioni | F7IG69Primary (citable) accession number: F7IG69 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | July 27, 2011 | |
Last modified: | August 12, 2020 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |