UniProtKB - F7HZS8 (F7HZS8_CALJA)
Protein
Aldedh domain-containing protein
Gene
ALDH8A1
Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 253 | PROSITE-ProRule annotation | 1 | |
Active sitei | 287 | PROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- retinal dehydrogenase activity Source: Ensembl
GO - Biological processi
- 9-cis-retinoic acid biosynthetic process Source: Ensembl
- retinal metabolic process Source: Ensembl
Keywordsi
Molecular function | OxidoreductaseUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Aldedh domain-containing proteinInterPro annotation |
Gene namesi | Name:ALDH8A1Imported |
Organismi | Callithrix jacchus (White-tufted-ear marmoset)Imported |
Taxonomic identifieri | 9483 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Platyrrhini › Cebidae › Callitrichinae › Callithrix › Callithrix |
Proteomesi |
|
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 24 – 483 | AldedhInterPro annotationAdd BLAST | 460 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 73 – 93 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the aldehyde dehydrogenase family.UniRule annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG2450, Eukaryota |
GeneTreei | ENSGT00940000156799 |
HOGENOMi | CLU_005391_0_0_1 |
InParanoidi | F7HZS8 |
OMAi | PMPIAAW |
OrthoDBi | 899961at2759 |
TreeFami | TF314129 |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
F7HZS8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAATKALLML ENFIDGKFLP CSSYIDSYDP STGEVYCRVP NSGKDEIEAA
60 70 80 90 100
VKAAREAFPG WSSRSPQERS RVLNQVADLL EQSLEEFAQA ESKDQGKTLA
110 120 130 140 150
LARTMDIPRS VQNFRFFASS ILHHISECTQ MDHLGCMHYT VRTPVGVAGL
160 170 180 190 200
ISPWNLPLYL LTWKIAPAMA AGNTVIAKPS ELTSVTAWML CRLLDEAGVP
210 220 230 240 250
PGVVNIVFGT GPRVGEALVS HPEVPLISFT GSQPTAERIT QLSAPHCKKL
260 270 280 290 300
SLELGGKNPA IIFEDANLDE CVPATVRSSF ANQGEICLCT SRIFVQKSIY
310 320 330 340 350
REFLKRFVEA TREWKVGIPS DPLASMGALI SKAHLEKVRS YVKKALAEGA
360 370 380 390 400
QIQCGEGVDK LSLPARNQAG YFMLPTVITD IRDESCCMTE EIFGPVTCVV
410 420 430 440 450
PFDSEEEVIE RANSLKYGLA AVVWSSNVGR VHRVAKKLQS GLVWTNCWLI
460 470 480
RELNLPFGGM KSSGIGREGA KDSYDFFTEI KTITIKH
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF7HXN3 | F7HXN3_CALJA | Aldedh domain-containing protein | ALDH8A1 | 433 | Annotation score: | ||
F7HXP8 | F7HXP8_CALJA | Aldedh domain-containing protein | ALDH8A1 | 437 | Annotation score: |
Sequence databases
RefSeqi | XP_002747097.1, XM_002747051.3 |
Genome annotation databases
Ensembli | ENSCJAT00000015455; ENSCJAP00000014652; ENSCJAG00000007652 |
GeneIDi | 100403774 |
KEGGi | cjc:100403774 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_002747097.1, XM_002747051.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9483.ENSCJAP00000014652 |
Genome annotation databases
Ensembli | ENSCJAT00000015455; ENSCJAP00000014652; ENSCJAG00000007652 |
GeneIDi | 100403774 |
KEGGi | cjc:100403774 |
Organism-specific databases
CTDi | 64577 |
Phylogenomic databases
eggNOGi | KOG2450, Eukaryota |
GeneTreei | ENSGT00940000156799 |
HOGENOMi | CLU_005391_0_0_1 |
InParanoidi | F7HZS8 |
OMAi | PMPIAAW |
OrthoDBi | 899961at2759 |
TreeFami | TF314129 |
Family and domain databases
Gene3Di | 3.40.309.10, 1 hit 3.40.605.10, 1 hit |
InterProi | View protein in InterPro IPR016161, Ald_DH/histidinol_DH IPR016163, Ald_DH_C IPR016160, Ald_DH_CS_CYS IPR029510, Ald_DH_CS_GLU IPR016162, Ald_DH_N IPR015590, Aldehyde_DH_dom |
Pfami | View protein in Pfam PF00171, Aldedh, 1 hit |
SUPFAMi | SSF53720, SSF53720, 1 hit |
PROSITEi | View protein in PROSITE PS00070, ALDEHYDE_DEHYDR_CYS, 1 hit PS00687, ALDEHYDE_DEHYDR_GLU, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7HZS8_CALJA | |
Accessioni | F7HZS8Primary (citable) accession number: F7HZS8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | July 27, 2011 | |
Last modified: | December 2, 2020 | |
This is version 53 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |