UniProtKB - F7HX68 (F7HX68_CALJA)
Protein
Submitted name:
AF4/FMR2 family member 1
Gene
AFF1
Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Names & Taxonomyi
Protein namesi | Submitted name: AF4/FMR2 family member 1Imported |
Gene namesi | Name:AFF1Imported |
Organismi | Callithrix jacchus (White-tufted-ear marmoset)Imported |
Taxonomic identifieri | 9483 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Platyrrhini › Cebidae › Callitrichinae › Callithrix › Callithrix |
Proteomesi |
|
Subcellular locationi
Nucleus
- transcription elongation factor complex Source: Ensembl
Keywords - Cellular componenti
NucleusARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 959 – 1221 | AF-4_CInterPro annotationAdd BLAST | 263 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 106 – 254 | DisorderedSequence analysisAdd BLAST | 149 | |
Regioni | 270 – 333 | DisorderedSequence analysisAdd BLAST | 64 | |
Regioni | 374 – 767 | DisorderedSequence analysisAdd BLAST | 394 | |
Regioni | 780 – 967 | DisorderedSequence analysisAdd BLAST | 188 | |
Regioni | 1102 – 1138 | DisorderedSequence analysisAdd BLAST | 37 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 106 – 175 | PolarSequence analysisAdd BLAST | 70 | |
Compositional biasi | 176 – 193 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 221 – 249 | PolarSequence analysisAdd BLAST | 29 | |
Compositional biasi | 319 – 333 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 379 – 434 | PolarSequence analysisAdd BLAST | 56 | |
Compositional biasi | 467 – 494 | PolarSequence analysisAdd BLAST | 28 | |
Compositional biasi | 593 – 613 | PolarSequence analysisAdd BLAST | 21 | |
Compositional biasi | 617 – 631 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 711 – 736 | PolarSequence analysisAdd BLAST | 26 | |
Compositional biasi | 789 – 841 | PolyampholyteSequence analysisAdd BLAST | 53 | |
Compositional biasi | 842 – 856 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 918 – 938 | PolyampholyteSequence analysisAdd BLAST | 21 | |
Compositional biasi | 939 – 961 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 1120 – 1138 | PolarSequence analysisAdd BLAST | 19 |
Sequence similaritiesi
Belongs to the AF4 family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | ENOG502QVDA, Eukaryota |
GeneTreei | ENSGT00950000182974 |
HOGENOMi | CLU_006484_0_0_1 |
InParanoidi | F7HX68 |
OMAi | HEREEKP |
TreeFami | TF326216 |
Family and domain databases
InterProi | View protein in InterPro IPR007797, AF4/FMR2 IPR043640, AF4/FMR2_CHD IPR043639, AF4_int |
PANTHERi | PTHR10528, PTHR10528, 1 hit |
Pfami | View protein in Pfam PF18876, AF-4_C, 1 hit PF18875, AF4_int, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F7HX68-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAFTERVNSS GSNLYNDDRN LLRIREKERR NQEAHQEKET FPEKIPLFGE
60 70 80 90 100
PYKTAKGDEL SSRIQNMLGN YEEVKEFLST KSHTHCLDAS ETRLGKPKYP
110 120 130 140 150
LIPDKGSSIP SNSFHTSIHH QSIHTPSSGP LSVGSISHNP KMSQPRTEPM
160 170 180 190 200
STLHAKSYGP PDSQHLTQDC LGQDGYSSTH HKKGDRKADG DHCASVTDSA
210 220 230 240 250
PERQISPLIS SLPSPVPPLS PIHSNQQTLS RMQGSNKVHG SNNNSKGYCP
260 270 280 290 300
AKSPKDLTVK VHDKEIPQDS LVAPPQAPSQ SFPPPSLPSK SVAMQQKPTA
310 320 330 340 350
YVRPMDGQDQ APSESPELKP LPEDYRQQTF EKTDLKVPAK VKLTKLKMPS
360 370 380 390 400
QSVEQTYSNE VHCVEEILKE MTHSWPPPLT AIHTPSTAEP SKFPFPTKDS
410 420 430 440 450
QHISSATQNQ KQYDTSSKTH PNSQQGTSSM LEDDLQLSDS EDSDSEQTPE
460 470 480 490 500
KPPSSSAPPS APQSLPEPVA SAHSSSAESE STSDSDSSSD SESESSSSDS
510 520 530 540 550
EENEPLETPA PEPEPPATNK WQLDNWLTKV SQPAVPPEGP GSTEPPQRHP
560 570 580 590 600
ESKGSSEGAA SQERSESKDP APKSSSRAPR APPEAPHPGK RSCQKSPAQQ
610 620 630 640 650
EPPQRQTVGT KQPKKPVKAS ARADSRASLH VEREPGLLPY GSRDQTSKDK
660 670 680 690 700
PKVKTKGRPR AAASRESKPA VPPSSEKKKH KSSLPAPSKA PSGPEPTKDN
710 720 730 740 750
VEDRSPEHFA LVPLTQSQGP SHSGGGSRTS GCRQAVVVQE DSRKDRLQLP
760 770 780 790 800
LRDTKLLSPL RDTPLPQSLM VKITLDLLSR IPQPPGKGSR QRKAEDKQPP
810 820 830 840 850
TGKKHSSEKR SSDSSSKLAK KRKGEAERDC DNKKIRLEKE IKPQSSSSSS
860 870 880 890 900
SSSHKESSKT KSSRPSSESS KKEMLPPPPV SSSSQKPAKP GHKRSRREAD
910 920 930 940 950
TCSQDPPKSA SSTKSSHKDS SIPKHRRVEG KGSRSSSEHK GSSGDTANPF
960 970 980 990 1000
SVPSLPNGNS KPGKPQVKFD KQQADLHMRE AKKLKQKAES MTDKVGKAFK
1010 1020 1030 1040 1050
YLEAVLSLIE CGIAMESESQ ASKSAYSVYS ETVDLIKFIM SLKSFSDVTA
1060 1070 1080 1090 1100
PTQEKIFAIL CMRCQSILNM AMFRCKKDIA IKYSRTLNKH FESSSKVAQA
1110 1120 1130 1140 1150
PSPCIARSTG TPSPLSPMPS PASSIGSQSS AGSVGSSGGM AATVNTPVTI
1160 1170 1180 1190 1200
QNMTSSYVTI TSHVLTAFDL WEQAEALTRK NKEFFAQLST NVCTLALNSS
1210 1220
LVDLVRYTRQ GFQQLQELTK TP
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8P0Z3 | A0A2R8P0Z3_CALJA | AF4/FMR2 family member 1 | AFF1 | 1,185 | Annotation score: | ||
A0A5F4WCG6 | A0A5F4WCG6_CALJA | AF4/FMR2 family member 1 | AFF1 | 1,175 | Annotation score: | ||
A0A5K1UYS2 | A0A5K1UYS2_CALJA | AF4/FMR2 family member 1 | AFF1 | 1,214 | Annotation score: |
Genome annotation databases
Ensembli | ENSCJAT00000011804; ENSCJAP00000011185; ENSCJAG00000006047 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9483.ENSCJAP00000011185 |
Genome annotation databases
Ensembli | ENSCJAT00000011804; ENSCJAP00000011185; ENSCJAG00000006047 |
Phylogenomic databases
eggNOGi | ENOG502QVDA, Eukaryota |
GeneTreei | ENSGT00950000182974 |
HOGENOMi | CLU_006484_0_0_1 |
InParanoidi | F7HX68 |
OMAi | HEREEKP |
TreeFami | TF326216 |
Family and domain databases
InterProi | View protein in InterPro IPR007797, AF4/FMR2 IPR043640, AF4/FMR2_CHD IPR043639, AF4_int |
PANTHERi | PTHR10528, PTHR10528, 1 hit |
Pfami | View protein in Pfam PF18876, AF-4_C, 1 hit PF18875, AF4_int, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7HX68_CALJA | |
Accessioni | F7HX68Primary (citable) accession number: F7HX68 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | June 20, 2018 | |
Last modified: | April 7, 2021 | |
This is version 46 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |