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Protein
Submitted name:

T-box 3

Gene

TBX3

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation
Biological processTranscription, Transcription regulationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
T-box 3Imported
Submitted name:
T-box transcription factor TBX3 isoform 2Imported
Gene namesi
Name:TBX3Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000017842

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini323 – 405TBXInterPro annotationAdd BLAST83

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili714 – 734Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG3585 Eukaryota
ENOG410XSTS LUCA
GeneTreeiENSGT00760000118897
OMAiPSQFAMG
OrthoDBiEOG091G0I8R
TreeFamiTF106341

Family and domain databases

CDDicd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
InterProiView protein in InterPro
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR022582 TBX
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PfamiView protein in Pfam
PF00907 T-box, 1 hit
PF12598 TBX, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00425 TBOX, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS01283 TBOX_1, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F7HRE2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSLSMRDPVI PGTSMAYHPF LPHRAPDFAM SAVLGHQPPF FPALTLPPNG
60 70 80 90 100
AAALSLPGAL AKPIMDQLVG AAETGIPFSS LGPQAHLRPL KTMEPEEEVE
110 120 130 140 150
DDPKVHLEAK ELWDQFHKRG TEMVITKSGR RMFPPFKVRC SGLDKKAKYI
160 170 180 190 200
LLMDIIAADD CRYKFHNSRW MVAGKADPEM PKRMYIHPDS PATGEQWMSK
210 220 230 240 250
VVTFHKLKLT NNISDKHGFT LAFPSDHATW QGNYSFGTQT ILNSMHKYQP
260 270 280 290 300
RFHIVRANDI LKLPYSTFRT YLFPETEFIA VTAYQNDKIT QLKIDNNPFA
310 320 330 340 350
KGFRDTGNGR REKRKQLTLQ SMRVFDERHK KENGTSDESS SEQAAFNCFA
360 370 380 390 400
QASSPAVSTV GTSNLKDLCP SEGESDAEAE SKEEHGPEAC DAAKISTTTS
410 420 430 440 450
EEPCRDKSSP AVKAHLFAAE RPRDSRRLDK ASPDSRHSPA TISSSTRGLG
460 470 480 490 500
AEERRSPGRE GAAPAKVEEA RALPGKEAFA PLTVQTDAAA AHLAQGPLPG
510 520 530 540 550
LGFAPGLAGQ QFFNGHPLFL HPGQFAMGGA FSSMAAAGMG PLLATVSGAS
560 570 580 590 600
TGVSGLDSTA MASAAAAQGL SGASAATLPF HLQQHVLASQ GLAMSPFGSL
610 620 630 640 650
FPYPYTYMAA AAAASSAAAS SSVHRHPFLN LNTMRPRLRY SPYSIPVPVP
660 670 680 690 700
DGSSLLTTAL PSMAAAAGPL DGKVAALASS PASVAVDSGS ELNSRSSTLS
710 720 730 740
SSSVSLSPKL CAEKEAATSE LQSIQRLVSG LEAKPDRSRS ASP
Length:743
Mass (Da):79,428
Last modified:June 20, 2018 - v2
Checksum:i551D94EFD4B96FE3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7I557F7I557_CALJA
T-box 3
TBX3
723Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01002632 mRNA Translation: JAB09229.1
RefSeqiXP_002753092.1, XM_002753046.3

Genome annotation databases

EnsembliENSCJAT00000018854; ENSCJAP00000017829; ENSCJAG00000009716
GeneIDi100397791

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMT01002632 mRNA Translation: JAB09229.1
RefSeqiXP_002753092.1, XM_002753046.3

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000017842

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCJAT00000018854; ENSCJAP00000017829; ENSCJAG00000009716
GeneIDi100397791

Organism-specific databases

CTDi6926

Phylogenomic databases

eggNOGiKOG3585 Eukaryota
ENOG410XSTS LUCA
GeneTreeiENSGT00760000118897
OMAiPSQFAMG
OrthoDBiEOG091G0I8R
TreeFamiTF106341

Family and domain databases

CDDicd00182 TBOX, 1 hit
Gene3Di2.60.40.820, 1 hit
InterProiView protein in InterPro
IPR008967 p53-like_TF_DNA-bd
IPR036960 T-box_sf
IPR022582 TBX
IPR001699 TF_T-box
IPR018186 TF_T-box_CS
PANTHERiPTHR11267 PTHR11267, 1 hit
PfamiView protein in Pfam
PF00907 T-box, 1 hit
PF12598 TBX, 1 hit
PRINTSiPR00937 TBOX
SMARTiView protein in SMART
SM00425 TBOX, 1 hit
SUPFAMiSSF49417 SSF49417, 1 hit
PROSITEiView protein in PROSITE
PS01283 TBOX_1, 1 hit
PS01264 TBOX_2, 1 hit
PS50252 TBOX_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF7HRE2_CALJA
AccessioniPrimary (citable) accession number: F7HRE2
Secondary accession number(s): F7HKU0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: June 20, 2018
Last modified: September 12, 2018
This is version 48 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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