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Entry version 37 (31 Jul 2019)
Sequence version 2 (30 Nov 2016)
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Protein

DBB domain-containing protein

Gene

BANK1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DBB domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BANK1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacaca mulatta (Rhesus macaque)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9544 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006718 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:70090 BANK1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMMUG00000008441 Expressed in 12 organ(s), highest expression level in spleen

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F7HKE9 baseline

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini185 – 312DBBInterPro annotationAdd BLAST128

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni416 – 466DisorderedSequence analysisAdd BLAST51
Regioni478 – 498DisorderedSequence analysisAdd BLAST21
Regioni525 – 569DisorderedSequence analysisAdd BLAST45
Regioni592 – 611DisorderedSequence analysisAdd BLAST20
Regioni624 – 656DisorderedSequence analysisAdd BLAST33

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi422 – 461PolyampholyteSequence analysisAdd BLAST40
Compositional biasi535 – 552PolyampholyteSequence analysisAdd BLAST18
Compositional biasi553 – 569AcidicSequence analysisAdd BLAST17
Compositional biasi626 – 647PolyampholyteSequence analysisAdd BLAST22

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHAS Eukaryota
ENOG410ZTCN LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008787

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.10140, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR017893 DBB_domain
IPR041340 PIK3AP1_TIR
IPR035897 Toll_tir_struct_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14545 DBB, 1 hit
PF18567 TIR_3, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01282 DBB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51376 DBB, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

F7HKE9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVNCHLKIGN TKDIIMIYEE DAEEWALYLT EVFLHVVQRE AILLYRLENF
60 70 80 90 100
SFRHLELLNL TSYKCKLLIL SNSLLKDLTP KKCQFLEKIL HSPESVVTLL
110 120 130 140 150
CGVMSSHQLY ELLNISQSRW EISTEQEPED YISVIQSIIF KDSEDYLEVN
160 170 180 190 200
IPTDLQVKHS GEISERKEIE ELPEASRNTI PLAVVLPAEI PCENPGEIFI
210 220 230 240 250
ILRDEVIGDT VEVEFTSNNK RIRTRPALWS KKVWCMKALE FPAGSVHVNV
260 270 280 290 300
YCDGIIKATT KIKYYPTAKA KECLFRMADS GESLCQNGIE ELDGVLTSIF
310 320 330 340 350
KHEIPYYEFQ SLQTEICSQN KYIHFKELPT LLHCAAKFGL KNLAIHLLQC
360 370 380 390 400
SGATWASKMK NMEGSDPARI AERHGHKELK KIFEDFSIQE IDTNNEQEND
410 420 430 440 450
YEEDIASFST YIPSTQNPAC HHESRKTYRQ SADVAEASEM EGEGKENGSD
460 470 480 490 500
MEAKHSPLEV GSESSEDQYD DLYVFIPGAD PENNSQEPLM SSRPPLPPPR
510 520 530 540 550
PIATAFQLER PHFTLPGTMV EVQMESSQNW GDPGVRQEKG DELKGEKDKK
560 570 580 590 600
EDEKEQEEEE EDPYTFAEID DSEYDMILAN LSIKKKTGSR SFIINRPPAP
610 620 630 640 650
TPRPTNIPPK EETTPYIAQV FQQKTARRQS DDDKFRGLPK KQDRARIESP
660 670 680 690 700
ASSTLRGCLT DGQEELILLQ EKVKNGKMSM DEALEKFKHW QMGKSGLEMI
710 720 730 740 750
QQEKLRQLRD CIIGKRPEEE NVYNKLTIVH HPVGKETVHN ENMFHNIPFS
760 770
NKLPAQPQVE KEFGFCCKKD H
Length:771
Mass (Da):88,296
Last modified:November 30, 2016 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i5AA61313BC2F1188
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6V3Y3F6V3Y3_MACMU
DBB domain-containing protein
BANK1
786Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5RF37A0A1D5RF37_MACMU
DBB domain-containing protein
BANK1
653Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
JSUE03034127 Genomic DNA No translation available.
JSUE03034128 Genomic DNA No translation available.
JSUE03034129 Genomic DNA No translation available.
JSUE03034130 Genomic DNA No translation available.
JSUE03034131 Genomic DNA No translation available.
JSUE03034132 Genomic DNA No translation available.
JSUE03034133 Genomic DNA No translation available.
JSUE03034134 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMMUT00000041941; ENSMMUP00000034950; ENSMMUG00000008441

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03034127 Genomic DNA No translation available.
JSUE03034128 Genomic DNA No translation available.
JSUE03034129 Genomic DNA No translation available.
JSUE03034130 Genomic DNA No translation available.
JSUE03034131 Genomic DNA No translation available.
JSUE03034132 Genomic DNA No translation available.
JSUE03034133 Genomic DNA No translation available.
JSUE03034134 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000041941; ENSMMUP00000034950; ENSMMUG00000008441

Organism-specific databases

VGNCiVGNC:70090 BANK1

Phylogenomic databases

eggNOGiENOG410IHAS Eukaryota
ENOG410ZTCN LUCA
GeneTreeiENSGT00390000008787

Gene expression databases

BgeeiENSMMUG00000008441 Expressed in 12 organ(s), highest expression level in spleen
ExpressionAtlasiF7HKE9 baseline

Family and domain databases

Gene3Di3.40.50.10140, 1 hit
InterProiView protein in InterPro
IPR017893 DBB_domain
IPR041340 PIK3AP1_TIR
IPR035897 Toll_tir_struct_dom_sf
PfamiView protein in Pfam
PF14545 DBB, 1 hit
PF18567 TIR_3, 1 hit
SMARTiView protein in SMART
SM01282 DBB, 1 hit
PROSITEiView protein in PROSITE
PS51376 DBB, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7HKE9_MACMU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7HKE9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: July 31, 2019
This is version 37 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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