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Protein
Submitted name:

Major epididymis-specific protein E4

Gene

WFDC2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Major epididymis-specific protein E4Imported
Submitted name:
WAP four-disulfide core domain 2Imported
Gene namesi
Name:WFDC2Imported
ORF Names:EGK_02361Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Sequence analysisAdd BLAST29
ChainiPRO_501409105830 – 123Sequence analysisAdd BLAST94

Expressioni

Gene expression databases

BgeeiENSMMUG00000002751 Expressed in 15 organ(s), highest expression level in lung
ExpressionAtlasiF7HII8 baseline

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000003691

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini28 – 65WAPInterPro annotationAdd BLAST38
Domaini72 – 122WAPInterPro annotationAdd BLAST51

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J36N Eukaryota
ENOG41125F3 LUCA
GeneTreeiENSGT00730000111410
OMAiDLNCTQE
OrthoDBiEOG091G0UW4

Family and domain databases

Gene3Di4.10.75.10, 2 hits
InterProiView protein in InterPro
IPR036645 Elafin-like_sf
IPR008197 WAP_dom
PfamiView protein in Pfam
PF00095 WAP, 2 hits
PRINTSiPR00003 4DISULPHCORE
SMARTiView protein in SMART
SM00217 WAP, 2 hits
SUPFAMiSSF57256 SSF57256, 2 hits
PROSITEiView protein in PROSITE
PS51390 WAP, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F7HII8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPACRLGSLA AALLGLLLFG FTLVPGTGAE KTGVCPKLQA DQNCTQECVS
60 70 80 90 100
DSECADNLKC CSAGCATFCS LPNDKEGSCP RVNRNFPQLG LCRDQCQVDS
110 120
QCPGRMKCCH NGCGKVSCVT PNF
Length:123
Mass (Da):12,929
Last modified:July 27, 2011 - v1
Checksum:i0D47B0955ADC52B4
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7HII1F7HII1_MACMU
Uncharacterized protein
WFDC2
75Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03004302 Genomic DNA No translation available.
CM001262 Genomic DNA Translation: EHH19656.1
RefSeqiXP_015004424.1, XM_015148938.1
UniGeneiMmu.12500

Genome annotation databases

EnsembliENSMMUT00000003907; ENSMMUP00000003691; ENSMMUG00000002751
GeneIDi710469
KEGGimcc:710469

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03004302 Genomic DNA No translation available.
CM001262 Genomic DNA Translation: EHH19656.1
RefSeqiXP_015004424.1, XM_015148938.1
UniGeneiMmu.12500

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000003691

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000003907; ENSMMUP00000003691; ENSMMUG00000002751
GeneIDi710469
KEGGimcc:710469

Organism-specific databases

CTDi10406

Phylogenomic databases

eggNOGiENOG410J36N Eukaryota
ENOG41125F3 LUCA
GeneTreeiENSGT00730000111410
OMAiDLNCTQE
OrthoDBiEOG091G0UW4

Gene expression databases

BgeeiENSMMUG00000002751 Expressed in 15 organ(s), highest expression level in lung
ExpressionAtlasiF7HII8 baseline

Family and domain databases

Gene3Di4.10.75.10, 2 hits
InterProiView protein in InterPro
IPR036645 Elafin-like_sf
IPR008197 WAP_dom
PfamiView protein in Pfam
PF00095 WAP, 2 hits
PRINTSiPR00003 4DISULPHCORE
SMARTiView protein in SMART
SM00217 WAP, 2 hits
SUPFAMiSSF57256 SSF57256, 2 hits
PROSITEiView protein in PROSITE
PS51390 WAP, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiF7HII8_MACMU
AccessioniPrimary (citable) accession number: F7HII8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 12, 2018
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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