Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

TNF receptor superfamily member 25

Gene

TNFRSF25

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
TNF receptor superfamily member 25Imported
Submitted name:
Tumor necrosis factor receptor superfamily member 25 isoform 2Imported
Gene namesi
Name:TNFRSF25Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei204 – 227HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501409101228 – 420Sequence analysisAdd BLAST393

Expressioni

Gene expression databases

BgeeiENSMMUG00000023677
ExpressionAtlasiF7GXU5 baseline

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000031179

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini75 – 118TNFR-CysInterPro annotationAdd BLAST44
Repeati75 – 118TNFR-CysPROSITE-ProRule annotationAdd BLAST44
Domaini335 – 416DeathInterPro annotationAdd BLAST82

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IKG3 Eukaryota
ENOG410YHT0 LUCA
GeneTreeiENSGT00530000064001
InParanoidiF7GXU5
KOiK05160
OrthoDBiEOG091G07LE
TreeFamiTF333916

Family and domain databases

CDDicd13420 TNFRSF25, 1 hit
InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR001368 TNFR/NGFR_Cys_rich_reg
IPR022329 TNFR_25
IPR034050 TNFRSF25_N
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00020 TNFR_c6, 1 hit
PRINTSiPR01972 TNFACTORR25
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SM00208 TNFR, 2 hits
SUPFAMiSSF47986 SSF47986, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS00652 TNFR_NGFR_1, 1 hit
PS50050 TNFR_NGFR_2, 1 hit

Sequencei

Sequence statusi: Complete.

F7GXU5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEQRSRGSAA VAAVSTALLL VLLGARAQGG TQSPRCDCAG DFHKKNGVFC
60 70 80 90 100
CRGCPAGHYL KAPCTEPCGN STCLLCPQDT FLAWENHHNS ECARCQACDE
110 120 130 140 150
QASQVALENC SAVADTRCGC KPGWFVECQV SQCVSSSPFY CQPCLDCRAL
160 170 180 190 200
HRHTRLLCSR RDTDCGTCLP GFYEHDDGCV SCPTSTLGSC PERCAAVCGW
210 220 230 240 250
RQMFWVQVLL AGLVVPLLLG ATLTYTYRHC WPHKPMVTAD EAGMEALTPP
260 270 280 290 300
PATHLSPSDK AHTLLVPPDS SEKICTVQLV DNSWTPGYPH TQEALCPQMT
310 320 330 340 350
WSWDQLPNRA LGPVPASTLL PESPVGSPTM MLQPGPQLYD VMDAVPARRW
360 370 380 390 400
KEFVRTLGLR EAEIEAVEVE IGRFRDQQYE MLKRWRQQQP AGLGAVYAAL
410 420
ERMGLDGCAE DLRSRLQRGP
Length:420
Mass (Da):46,063
Last modified:November 30, 2016 - v2
Checksum:i5EDB066BDC4CA84B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03000160 Genomic DNA No translation available.
JU477638 mRNA Translation: AFH34442.1
RefSeqiXP_014998005.1, XM_015142519.1
UniGeneiMmu.24755

Genome annotation databases

EnsembliENSMMUT00000033315; ENSMMUP00000031179; ENSMMUG00000023677
GeneIDi703744
KEGGimcc:703744

Similar proteinsi

Entry informationi

Entry nameiF7GXU5_MACMU
AccessioniPrimary (citable) accession number: F7GXU5
Secondary accession number(s): H9ZES6
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: May 23, 2018
This is version 42 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health