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Protein

Putative hydroxypyruvate isomerase

Gene

HYI

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).UniRule annotation

Catalytic activityi

Hydroxypyruvate = 2-hydroxy-3-oxopropanoate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei150Proton donor/acceptorUniRule annotation1
Active sitei249Proton donor/acceptorUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionIsomeraseUniRule annotationImported
LigandPyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Putative hydroxypyruvate isomeraseUniRule annotation (EC:5.3.1.22UniRule annotation)
Gene namesi
Name:HYIImported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Interactioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000006476

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini25 – 220AP_endonuc_2InterPro annotationAdd BLAST196

Sequence similaritiesi

Belongs to the hyi family.UniRule annotation

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
InParanoidiF7GQR5
KOiK01816
OrthoDBiEOG091G0KZU
TreeFamiTF312858

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit

Sequencei

Sequence statusi: Complete.

F7GQR5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPLRFSANL SWLFPELPGL LPRLRAAGSS GFEAAEVAWP YAEPPEALAR
60 70 80 90 100
AAREAGLRLV LINTPPGDHE KGEMGLGAVP GRQEAFREGL EQAVRYAKAL
110 120 130 140 150
GCPRIHLMAG RVPQGADPAA VKAEMETVFL ENLRHAAGVL AQEDLVGLLE
160 170 180 190 200
PINTRITDPQ YFLDTPQQAA AILQKVGRPN LQLQMDIFHW QIMDGNLTGN
210 220 230 240 250
IREFLPIVGH VQVAQVPGRG EPSSPGELNF PYLFQLLEDE GYKGFVGCEY
260 270
RPQGDTVEGL SWLRSYWDRR GHPGAGQ
Length:277
Mass (Da):30,364
Last modified:June 20, 2018 - v2
Checksum:iE1660F1577B06F17
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMQ01002913 mRNA Translation: JAB38938.1
RefSeqiXP_002807044.2, XM_002806998.4

Genome annotation databases

EnsembliENSCJAT00000006840; ENSCJAP00000006476; ENSCJAG00000003560
GeneIDi100410710
KEGGicjc:100410710

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GAMQ01002913 mRNA Translation: JAB38938.1
RefSeqiXP_002807044.2, XM_002806998.4

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000006476

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSCJAT00000006840; ENSCJAP00000006476; ENSCJAG00000003560
GeneIDi100410710
KEGGicjc:100410710

Organism-specific databases

CTDi81888

Phylogenomic databases

eggNOGiKOG4518 Eukaryota
COG3622 LUCA
GeneTreeiENSGT00390000005462
InParanoidiF7GQR5
KOiK01816
OrthoDBiEOG091G0KZU
TreeFamiTF312858

Family and domain databases

InterProiView protein in InterPro
IPR026040 HyI-like
IPR036237 Xyl_isomerase-like_sf
IPR013022 Xyl_isomerase-like_TIM-brl
PfamiView protein in Pfam
PF01261 AP_endonuc_2, 1 hit
PIRSFiPIRSF006241 HyI, 1 hit
SUPFAMiSSF51658 SSF51658, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF7GQR5_CALJA
AccessioniPrimary (citable) accession number: F7GQR5
Secondary accession number(s): U3DJV3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: June 20, 2018
Last modified: September 12, 2018
This is version 29 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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