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Entry version 63 (29 Sep 2021)
Sequence version 3 (11 Dec 2019)
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Protein
Submitted name:

Uncharacterized protein

Gene

PKHD1

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.ARBA annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00143

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PKHD1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13616 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002280 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei3863 – 3886HelicalSequence analysisAdd BLAST24

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 26Sequence analysisAdd BLAST26
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_503017017927 – 4081Sequence analysisAdd BLAST4055

Keywords - PTMi

GlycoproteinARBA annotation

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMODG00000018828, Expressed in adult mammalian kidney and 9 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
13616.ENSMODP00000023481

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini330 – 490PA14InterPro annotationAdd BLAST161
Domaini1939 – 2059G8InterPro annotationAdd BLAST121
Domaini2753 – 2879G8InterPro annotationAdd BLAST127

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni3894 – 3929DisorderedSequence analysisAdd BLAST36

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502QR85, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160697

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000057_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F7GKG2

Identification of Orthologs from Complete Genome Data

More...
OMAi
ETVHNAD

TreeFam database of animal gene trees

More...
TreeFami
TF329582

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.160.20.10, 2 hits
2.60.40.10, 5 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR039448, Beta_helix
IPR019316, G8_domain
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR007742, NosD_dom
IPR037524, PA14/GLEYA
IPR006626, PbH1
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR028839, PKHD1

The PANTHER Classification System

More...
PANTHERi
PTHR46769:SF1, PTHR46769:SF1, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13229, Beta_helix, 1 hit
PF10162, G8, 2 hits
PF05048, NosD, 1 hit
PF01833, TIG, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01225, G8, 2 hits
SM00429, IPT, 5 hits
SM00710, PbH1, 8 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF51126, SSF51126, 2 hits
SSF81296, SSF81296, 6 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51484, G8, 2 hits
PS51820, PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F7GKG2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSHLVCKMIA CLYSLMTIEM ILLAASCRNW HIVPDEGSVA GGTWITIVFD
60 70 80 90 100
GLEQSFLYPT SGSQLEISLV NVDLPWLPHV PCDVSPVYED VALLRCQTRS
110 120 130 140 150
LQWETQEGLY YLEVRSGGQL FSSMSKGSWD NCTFKFSKAQ TPIVYQVNPP
160 170 180 190 200
SGVPGNLIQV HGWIITGRTE TFDNDVEYID SPLTLQAQGG EWITPCSLVD
210 220 230 240 250
REKGNRYPVE EDHGIGVLQC RVEGHYIGSQ NVSFSVFNKG KSTVHKDAWL
260 270 280 290 300
ISAKQELFLY QTYSEIWSVF PVSGSLGGGT DITITGDFFD YSAQVTIAGI
310 320 330 340 350
PCRIKYISPR KIECTTRPLK QDTKLTSPHP GNRGLLFEVG DAQEDLDPTN
360 370 380 390 400
TTPGYRWQIV PNASSPFGFW SEEGQHFRAR LSGFFVSPET NNYTFWIQAD
410 420 430 440 450
SPASLYFSQS ADPENKMKVA FIQAGATDWF NSWERNGHLE AWQQKSQKLE
460 470 480 490 500
LLGGAKYYLE ANHYGVTPSH GMSIGVQIHN TWLNPDVVNS YHREKLQIRA
510 520 530 540 550
RAQRIPEIQI LNVTGTGTFC LTWDGVSSQP VTTNATAAEI QAAIEELLTV
560 570 580 590 600
KCKLEPLSAQ ILLWFGFEKG LEDSGPDGDL TSGTEPFCGR FSIHQPQFLV
610 620 630 640 650
RTSEAMQMRY QLDQYTHLCF AYKGHMNDTM TLSVSFTNKF HKPVKKKIVC
660 670 680 690 700
EWNPEQLTPE SWKFVCNELW ETCVRHSGGL YTRLANSPVL VHRIDMSPLE
710 720 730 740 750
HEKSHFYIDE IIVADRNLTV SQVHSRIARP GGKLIESLSV TGAPSTYNIT
760 770 780 790 800
LWMAGCGCEL PLIQPCYLPP EEANESSRRV SVTVQRLQRM SPALEGHFRI
810 820 830 840 850
QLPNTVISGI PVHISAHDLL ELLQNSGDDF ASQFLNVSDF KVQKDLSSCY
860 870 880 890 900
EHVWTLMWMS QIGDLPNIIR VSAENLTGII PTVSTRVVYD GGIFLGPIFG
910 920 930 940 950
DMLVTPNTYP QVTMRVNDIP AHCSGSCSFQ YLQESTPLVQ AVWYSYDDDI
960 970 980 990 1000
NLLVCIMGSG FPGDSGALKI KVNQQICEIT FSNQTYVTCK MGFLPIGKYQ
1010 1020 1030 1040 1050
VVMLVRHLGF ALNVTGGEGI HFNIEPKLKI MEPSVAPEIG GLWTTIQGTN
1060 1070 1080 1090 1100
LEHVSLVLFG SQPCPVNITT RKIERIQCKV PPWIDFQGNS SRILVNVTII
1110 1120 1130 1140 1150
TRNVSVSYPE AFKYSPSLNP VILSLSRIRS NTAGDQTLFI GTTSLANYTD
1160 1170 1180 1190 1200
LNVEVHIQDT LATILKQVPQ GLEVALPSLP AGWHNISVTM NGVNIIAEGV
1210 1220 1230 1240 1250
DLQIQYITEV FKIEPCCGSL LGGTTLTISG IGFSKDPSLV TVSVGNQTCN
1260 1270 1280 1290 1300
IVNSTEETIW CETSAAPHLP GTESQAVMVP IEVLVGNIRA HHGPSFGLGK
1310 1320 1330 1340 1350
DFTFIYHTAL TPFVTAMQGQ IRGDMLEFQV EGNNLSESVV LLGHMKCDLE
1360 1370 1380 1390 1400
LQFFSFNRTQ YFCSLPLANM EAGIYPIQVF RKDIGFANIS AVPHSFTVAP
1410 1420 1430 1440 1450
QITDIFPTHG SVCGGTWLTV IGLAFKSRMK LVQIDLSDHH TCAIWKWNDQ
1460 1470 1480 1490 1500
MILCQVSFVG HLPKASLAMN VTITANGISS ECQGNCTFYL QEESTPIVET
1510 1520 1530 1540 1550
LTTSVSGTLT TMLIGGQKLA TATDELVVLV DDHLSCDITF YNATWVECQL
1560 1570 1580 1590 1600
SDLGPGLHHF SLLNGRSGFA CLGTLAPHFS IVPQVLGYHP QNFSINGGGL
1610 1620 1630 1640 1650
LTIEGTTLRG KNTTSVLIGH QPCFTVNISS VLIQCIVPPG NGTVDLEIEV
1660 1670 1680 1690 1700
DGNLIDVGII SYSEVFTPAL LFILQIDGLI VTFMVARTSG AKNMQIFIGA
1710 1720 1730 1740 1750
SPCVGILGNY TVLQCSVAQL PTGEYQVKGF DRFRGWASST LVFTSNVTIT
1760 1770 1780 1790 1800
SIHRNFGCLS GSLLHVHGSG FSPGNMSAEV CGVPCQVLDN ATVTNFSCLV
1810 1820 1830 1840 1850
LPLDASLAFL CNLRPLEESC KATKTTYIQC ELTVTVGTIN LLRSWSYIYM
1860 1870 1880 1890 1900
CEENPWCSLV LDHQVDSSLG LFSGLFISPK VERDEVLIYN SSCNITMETE
1910 1920 1930 1940 1950
AEMECEAPNQ PITAKITEIR KNWGQNTQLQ VCRRWSRAHS WIPQGWPQDG
1960 1970 1980 1990 2000
DNVTVESGQT LLLDITTSVL SMLHIKGGKL IFTGPGPIEL HAHCILVSHG
2010 2020 2030 2040 2050
GELQIGSLDE PYHGKALIYL HGSSSTTFYP YGAKFLAVRN GTLSLHGLRP
2060 2070 2080 2090 2100
EVSITHLRTA AQANDTMLAL EDHVDWHPGE EVIISGVTLE GSQRQEEIAI
2110 2120 2130 2140 2150
IESTHGANLH LQSPLRYSHG ILEHNIGGHH IALRVTVALL SRNIAIQGHL
2160 2170 2180 2190 2200
TNEGMAHLQL CTEAKIPEDD FQQCLYLRSE KNLGSMNLGA VVIVQSLPGE
2210 2220 2230 2240 2250
PSQVQLQGVQ FQYMGQAFQK HLCALNVIGP IRDSYIRSCS VWDSFSRGLS
2260 2270 2280 2290 2300
LSRTSNLIVE NNVFYNILGH GLLVGTHMEM KHFPWKAVPR RKTDWSRQGN
2310 2320 2330 2340 2350
IVRSNVVIGV FGTEGLSNIE VLSPAGIYIQ DPISVVERNM VCAAGYGYFF
2360 2370 2380 2390 2400
HLGTSETSKA PLRSFTQNVA HSCTRYGLLV YPRFEPPQVN DTGPTLFQNF
2410 2420 2430 2440 2450
TAWGSQGGVQ IFRSSNLQLK NFQIYSCKDF GIDILESDAN SSIVESLLLS
2460 2470 2480 2490 2500
HYSSKKGSSC MSAGIKTPKR QELLVSKTTF VNFDQKNCIS LRTCSSCYRG
2510 2520 2530 2540 2550
QGGFTVKTEQ LKFLNSPNRI AFPFPHAAIL EDLDGSVSGN KGRYLLASVE
2560 2570 2580 2590 2600
NLASSCQVNQ SFGQTVKGSV CGPDVIFHRM SIGLAEAPDV AYDLTVTDSK
2610 2620 2630 2640 2650
NQTMTINFVN DTLSNLYGWM ALLLDQDTYL LRFEASWIKS SLQYSATFDN
2660 2670 2680 2690 2700
FTSGNYLLVV HKDLQPYADI LVICGTRIGQ SLLSSPSATR DQACDWFFNS
2710 2720 2730 2740 2750
HLGELTYLVS GEGQVHLTLL VKERIIPATP VPSDVPKSIL KWSHPGTWQG
2760 2770 2780 2790 2800
VEEGWGGYNH TTPAPGDDVV ILPNKTILVD TDLPFLKGLY VLGTLEFPVN
2810 2820 2830 2840 2850
RSNVLNVACI IVAGGELKVG TFPEPLHKGQ KLLIQLRASE GDYCDRLDGI
2860 2870 2880 2890 2900
NIAPGTFGVY GKVQLHSAYP RKAWTHLGAD IASGNERILV KDEVDWRPQD
2910 2920 2930 2940 2950
KIVLSSSSYE PHEAEILTIK EVMGQNVRLY EHLNHRHLGS SHSMEDGRHI
2960 2970 2980 2990 3000
SLAAEVGLLT RNIKIQPDAP CGGRMVVGSF QKPNGEEFSG TLQLSNVEIQ
3010 3020 3030 3040 3050
NFGSLLYPSI EFNNVSLGSW MISSSVHQSC GGGIRVSSSK SIFLHDNILF
3060 3070 3080 3090 3100
DTTGHGIDLE GQNHSLIKNL IVLTKQPQRA MDWVTGIKVN QVNDANLIGN
3110 3120 3130 3140 3150
AVAGSERIGF HIKGHDCSMA ENPWVGNVVH SSLHGLHVYK GDGLYNCTKI
3160 3170 3180 3190 3200
SGFLSYKNFD YGAMFHVENN LEINNMTLVD NVVGLLPLVY ASFPEQCSLE
3210 3220 3230 3240 3250
KKQIVLRNSI IVATSSSFDC IEDRIKPLSA DFTSRDRPPS NPRGGRVGIL
3260 3270 3280 3290 3300
WPGFTAEPNQ WPQDAWHKVK NYPSVSGIMR LEGVTFSDFV KSCYSNDLDV
3310 3320 3330 3340 3350
CILPNPDSPG IIPPIMAERT KMLKVKDQNK FYFSLPWLRK ETGKIVCPEL
3360 3370 3380 3390 3400
DCESPMKYLF KDLDGSVLDL PPPISVFPKS KSEWVGSCFN TGIFREDRKC
3410 3420 3430 3440 3450
TYRPSMQSFV CKQMDYILLI LDNITIAPGK KIPSSVVSVT SGFVETFSSI
3460 3470 3480 3490 3500
VAHSSCSASL SIPAFYSLLP TNSLTKICFV NGVPQAMRFY LIGSERSSKV
3510 3520 3530 3540 3550
LAVFYPELQS PRVFFRGQFI PPTSVLSDSW QENGATGTNH FSFMDNLLYI
3560 3570 3580 3590 3600
LLQGDEPVEV QSAISIYVAF TVTLSSALED WEPAIDQRLA HFLQIGQDHI
3610 3620 3630 3640 3650
RIVHILPGGE RILKAFADGV AKRKHHCPSG TPCTNCHRLG QHRNFMRKMK
3660 3670 3680 3690 3700
MWVPPSTFSE TISKVVVIEI GDLSGIGNAK VASSLSTDGL QCLVHRIITS
3710 3720 3730 3740 3750
QQTGELQEAL NMPVEALLIS QSAGVFTSGN SSSLDTGSVV YIQPFTLSVQ
3760 3770 3780 3790 3800
VQPSSGEVGI ELPVQPHLVF LDKQGRVVES LGPPSEPWIV TVSLEGASET
3810 3820 3830 3840 3850
VLKGHTHAEA HQGRVSFSNL AVSSSGSNWY FLFTVTSPPG AKFNVRSEPF
3860 3870 3880 3890 3900
AVLPVNKGEK STILMALVLC SAASWMALCF LVFCWLKKSK KTKTKETSGP
3910 3920 3930 3940 3950
QVADRKKNPQ VKHNSHPTRN QERLEETKKG TTVIQEDMRQ KAIQGKPNQS
3960 3970 3980 3990 4000
SYQQSLNGLT RRMIRTGHRE GGRGEVPTEV IAHLPSQGHD DLSSGTPAQQ
4010 4020 4030 4040 4050
VPIQEVRDWK DGQAHLLGYH PTEQDQLLVL YPSFDQEGQK LPEQRHADRK
4060 4070 4080
SDHLGYYWDR KAKSESFHLH SLQQAPLQGQ L
Length:4,081
Mass (Da):450,411
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAAD97A4CEEA6507D
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5F8G609A0A5F8G609_MONDO
Uncharacterized protein
PKHD1
4,016Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8H9H7A0A5F8H9H7_MONDO
Uncharacterized protein
PKHD1
4,092Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8HHC6A0A5F8HHC6_MONDO
Uncharacterized protein
PKHD1
4,035Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007484143.1, XM_007484081.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMODT00000023897; ENSMODP00000023481; ENSMODG00000018828

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100016226

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mdo:100016226

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007484143.1, XM_007484081.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Protein-protein interaction databases

STRINGi13616.ENSMODP00000023481

Genome annotation databases

EnsembliENSMODT00000023897; ENSMODP00000023481; ENSMODG00000018828
GeneIDi100016226
KEGGimdo:100016226

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
5314

Phylogenomic databases

eggNOGiENOG502QR85, Eukaryota
GeneTreeiENSGT00940000160697
HOGENOMiCLU_000057_1_0_1
InParanoidiF7GKG2
OMAiETVHNAD
TreeFamiTF329582

Enzyme and pathway databases

UniPathwayiUPA00143

Gene expression databases

BgeeiENSMODG00000018828, Expressed in adult mammalian kidney and 9 other tissues

Family and domain databases

Gene3Di2.160.20.10, 2 hits
2.60.40.10, 5 hits
InterProiView protein in InterPro
IPR039448, Beta_helix
IPR019316, G8_domain
IPR013783, Ig-like_fold
IPR014756, Ig_E-set
IPR002909, IPT_dom
IPR007742, NosD_dom
IPR037524, PA14/GLEYA
IPR006626, PbH1
IPR012334, Pectin_lyas_fold
IPR011050, Pectin_lyase_fold/virulence
IPR028839, PKHD1
PANTHERiPTHR46769:SF1, PTHR46769:SF1, 1 hit
PfamiView protein in Pfam
PF13229, Beta_helix, 1 hit
PF10162, G8, 2 hits
PF05048, NosD, 1 hit
PF01833, TIG, 6 hits
SMARTiView protein in SMART
SM01225, G8, 2 hits
SM00429, IPT, 5 hits
SM00710, PbH1, 8 hits
SUPFAMiSSF51126, SSF51126, 2 hits
SSF81296, SSF81296, 6 hits
PROSITEiView protein in PROSITE
PS51484, G8, 2 hits
PS51820, PA14, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7GKG2_MONDO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7GKG2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: September 29, 2021
This is version 63 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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