Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 50 (12 Aug 2020)
Sequence version 3 (11 Dec 2019)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

TSC22D1

Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TSC22D1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMonodelphis domestica (Gray short-tailed opossum)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13616 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMetatheriaDidelphimorphiaDidelphidaeMonodelphis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002280 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMODG00000014919, Expressed in uterine wall and 21 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
13616.ENSMODP00000018652

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni20 – 111DisorderedSequence analysisAdd BLAST92
Regioni127 – 305DisorderedSequence analysisAdd BLAST179
Regioni329 – 350DisorderedSequence analysisAdd BLAST22
Regioni454 – 530DisorderedSequence analysisAdd BLAST77
Regioni570 – 591DisorderedSequence analysisAdd BLAST22
Regioni660 – 682DisorderedSequence analysisAdd BLAST23
Regioni887 – 933DisorderedSequence analysisAdd BLAST47

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi174 – 194PolarSequence analysisAdd BLAST21
Compositional biasi218 – 241BasicSequence analysisAdd BLAST24
Compositional biasi285 – 305PolarSequence analysisAdd BLAST21
Compositional biasi456 – 482PolarSequence analysisAdd BLAST27
Compositional biasi510 – 530PolarSequence analysisAdd BLAST21
Compositional biasi887 – 925PolarSequence analysisAdd BLAST39

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4797, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159144

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_010450_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F7FVT4

Database of Orthologous Groups

More...
OrthoDBi
1602203at2759

TreeFam database of animal gene trees

More...
TreeFami
TF318837

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F7FVT4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHQPPEATAA AAAAAADLGA RKMAHPAAVP RRGSSSSSGG GGSGGSAPLS
60 70 80 90 100
AAGPGVGSHA APTEDYAREA SLPGAAAGGP APPPPPQSLH LLSQAPSLPA
110 120 130 140 150
PPGGAQMKKK SGFQITSVTP AQISASISSN NSIAEDTESY DDLDESHTED
160 170 180 190 200
LSSSEILDVS LSRATDLGEP ERSSSEETLN NFQEAETPGA VSPNQPHLPQ
210 220 230 240 250
HHLPHHPPQN VVINGSAHPH HLHHHHHHHG HHLHHGHHHP SHAGVVSAAA
260 270 280 290 300
SGGPPPSPVA RKLSTAGSSD SVLPAAPPSA ASAAGTPASL MTNVRNPSTP
310 320 330 340 350
GSLGINPIAG TGTINNVNVS AGGSVNPNVT NSMPGNANVP SSTIPSTSGG
360 370 380 390 400
SALPVAGSSV NVNILSGMGN GTTASVSSAP AQATAMAVGS AGSAQQQPPA
410 420 430 440 450
AGTSRFRVVK LDSSSEPFKK GRWTCTEFYE KENTATATEG GAVNKVVETV
460 470 480 490 500
RQNPVEGASE RESTSGSSVS STVSTLSHYT ESVGSGEMGA PTVVPQQGLP
510 520 530 540 550
VPAAPQPGDF SSSAGAQAGS AGGLPQSISQ SQIAPVQLHS QELNYTPQKQ
560 570 580 590 600
GGQPPLQASI SAATGLQSPP VNLMAVPPPL GQQPPVSSLA QPHLSYSQSA
610 620 630 640 650
PLVQTPLPVV APPQLQYGQQ QQTVATQVAP GHVQSVSQNP VPASIPEYVQ
660 670 680 690 700
HQQVLQTPVP SLPPNSAGVG AAPAMPVGQP QSIQPSVQST AVQAQPAGAP
710 720 730 740 750
SQPLGHGQPA MPPIAASGQV LNVGQPVNIQ PATTQVTASL VQQSATPPSQ
760 770 780 790 800
VVPPSQPGII QGIQASTSSL PQQLVIAPQS NLVTVQPQVQ GAESIAQGIT
810 820 830 840 850
SQQLPPVSPL PTASSVPAAN QVGSAVPPGI SAAPTNLGPP QNIAQTSAIQ
860 870 880 890 900
NGNLVQSVSQ PPLVATNINL PVTQQIPLSS TQFPTQSLTQ SIGSQSEEAR
910 920 930 940 950
QSVEHSLVGG PQTLSGESSG GLASGSDGSG GALAASGSAS LFPLKVLPLT
960 970 980 990 1000
TPLVDGEDES ASPLPEVQGM ILEPQIQPRP RRAFDVRGPL SPLNHWRQNI
1010 1020
QLLERVGKNN KQSLLEAHGF ISGI
Length:1,024
Mass (Da):103,014
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE2DE8D00893A3EF8
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A5F8HA64A0A5F8HA64_MONDO
Uncharacterized protein
TSC22D1
1,062Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8GGE5A0A5F8GGE5_MONDO
Uncharacterized protein
TSC22D1
144Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8GH47A0A5F8GH47_MONDO
Uncharacterized protein
TSC22D1
1,017Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007501625.1, XM_007501563.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMODT00000018989; ENSMODP00000018652; ENSMODG00000014919

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100012031

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007501625.1, XM_007501563.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi13616.ENSMODP00000018652

Genome annotation databases

EnsembliENSMODT00000018989; ENSMODP00000018652; ENSMODG00000014919
GeneIDi100012031

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8848

Phylogenomic databases

eggNOGiKOG4797, Eukaryota
GeneTreeiENSGT00940000159144
HOGENOMiCLU_010450_0_0_1
InParanoidiF7FVT4
OrthoDBi1602203at2759
TreeFamiTF318837

Gene expression databases

BgeeiENSMODG00000014919, Expressed in uterine wall and 21 other tissues

Family and domain databases

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7FVT4_MONDO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7FVT4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: August 12, 2020
This is version 50 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again