UniProtKB - F7F5C3 (F7F5C3_MONDO)
Protein
Submitted name:
Regulatory factor X2
Gene
RFX2
Organism
Monodelphis domestica (Gray short-tailed opossum)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Regulatory factor X2Imported |
Gene namesi | Name:RFX2Imported |
Organismi | Monodelphis domestica (Gray short-tailed opossum)Imported |
Taxonomic identifieri | 13616 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Metatheria › Didelphimorphia › Didelphidae › Monodelphis |
Proteomesi |
|
Expressioni
Gene expression databases
Bgeei | ENSMODG00000001398, Expressed in female gonad and 21 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 190 – 265 | RFX-type winged-helixInterPro annotationAdd BLAST | 76 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 284 – 323 | DisorderedSequence analysisAdd BLAST | 40 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 301 – 323 | PolarSequence analysisAdd BLAST | 23 |
Phylogenomic databases
eggNOGi | KOG3712, Eukaryota |
GeneTreei | ENSGT00980000198514 |
HOGENOMi | CLU_010393_1_1_1 |
InParanoidi | F7F5C3 |
OrthoDBi | 346630at2759 |
TreeFami | TF321340 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR003150, DNA-bd_RFX IPR039779, RFX-like IPR007668, RFX1_trans_act IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12619, PTHR12619, 1 hit |
Pfami | View protein in Pfam PF04589, RFX1_trans_act, 1 hit PF02257, RFX_DNA_binding, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51526, RFX_DBD, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
F7F5C3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQNPEGGSDS ATSVALRTSA STQAPVVQPV AASHHVVLAQ SPPNFRSVAQ
60 70 80 90 100
VQPVQHVYPT QVQYVEGGDT VYTNGAIRTA YSYNTEAQIY APSSAASYFE
110 120 130 140 150
SPGGGAQVTT VASSPSAIPS HSMVGITMDV GGSQIISSSG AYLIHGGMDN
160 170 180 190 200
TRHSLSHTSR SSPATLEMAI ENLQKNEGIT SHKSSLLNSH LQWLLDNYET
210 220 230 240 250
AEGVSLPRSS LYNHYLRHCQ EHKLDPVNAA SFGKLIRSVF VGLRTRRLGT
260 270 280 290 300
RGNSKYHYYG IRLKPDSPLN RLQEDTQYMA MRQQPIHQKQ RYRPAQKMDG
310 320 330 340 350
LGESGSNSNL HATPEQSVAA QSQHHQQFID VSHVFPEFPA PDLGSVFLQE
360 370 380 390 400
GITVNDIKTL QLLYRRHCEA TLDVVMNLQF HYIEKLWLSF WSSKPPSGEG
410 420 430 440 450
STALPSSEEE HEVTVIPKDK LITLCKYDPI LKWMRNCDHI LYQALVEILI
460 470 480 490 500
PDVLRPVPST LTQAIRNFAK SLEGWLTNAM SDFPQQIIQT KVGVVSAFAQ
510 520 530 540 550
TLRRYTSLNH LAQAARAVLQ NTSQINQMLS DLNRVDFANV QEQASWVCQC
560 570 580 590 600
EESVVQKLEQ DFKLTLQQQS SLDQWATWLD NVVTQVLKHH AGSPSFPKAA
610 620 630 640 650
RQFLLKWSFY SSMVIRDLTL RSAASFGSFH LIRLLYDEYM FYLVEHRVAE
660 670 680
ATGETPIAVM GEVRALSIKV LITLDINRKD
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F8G3V1 | A0A5F8G3V1_MONDO | Regulatory factor X2 | RFX2 | 685 | Annotation score: | ||
A0A5F8G591 | A0A5F8G591_MONDO | Regulatory factor X2 | RFX2 | 680 | Annotation score: | ||
A0A5F8GAT4 | A0A5F8GAT4_MONDO | Regulatory factor X2 | RFX2 | 705 | Annotation score: | ||
A0A5F8H914 | A0A5F8H914_MONDO | Regulatory factor X2 | RFX2 | 686 | Annotation score: |
Genome annotation databases
Ensembli | ENSMODT00000001725; ENSMODP00000001690; ENSMODG00000001398 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 13616.ENSMODP00000001690 |
Genome annotation databases
Ensembli | ENSMODT00000001725; ENSMODP00000001690; ENSMODG00000001398 |
Phylogenomic databases
eggNOGi | KOG3712, Eukaryota |
GeneTreei | ENSGT00980000198514 |
HOGENOMi | CLU_010393_1_1_1 |
InParanoidi | F7F5C3 |
OrthoDBi | 346630at2759 |
TreeFami | TF321340 |
Gene expression databases
Bgeei | ENSMODG00000001398, Expressed in female gonad and 21 other tissues |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR003150, DNA-bd_RFX IPR039779, RFX-like IPR007668, RFX1_trans_act IPR036388, WH-like_DNA-bd_sf IPR036390, WH_DNA-bd_sf |
PANTHERi | PTHR12619, PTHR12619, 1 hit |
Pfami | View protein in Pfam PF04589, RFX1_trans_act, 1 hit PF02257, RFX_DNA_binding, 1 hit |
SUPFAMi | SSF46785, SSF46785, 1 hit |
PROSITEi | View protein in PROSITE PS51526, RFX_DBD, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7F5C3_MONDO | |
Accessioni | F7F5C3Primary (citable) accession number: F7F5C3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | August 12, 2020 | |
This is version 55 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |