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Protein
Submitted name:

Cyclin A1

Gene

ccna1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Keywordsi

Molecular functionCyclinUniRule annotationSAAS annotation

Enzyme and pathway databases

ReactomeiR-XTR-1538133 G0 and Early G1
R-XTR-174184 Cdc20:Phospho-APC/C mediated degradation of Cyclin A
R-XTR-176408 Regulation of APC/C activators between G1/S and early anaphase
R-XTR-187577 SCF(Skp2)-mediated degradation of p27/p21
R-XTR-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-XTR-2559586 DNA Damage/Telomere Stress Induced Senescence
R-XTR-5689880 Ub-specific processing proteases
R-XTR-5693607 Processing of DNA double-strand break ends
R-XTR-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
R-XTR-6804756 Regulation of TP53 Activity through Phosphorylation
R-XTR-6804757 Regulation of TP53 Degradation
R-XTR-68911 G2 Phase
R-XTR-68949 Orc1 removal from chromatin
R-XTR-69017 CDK-mediated phosphorylation and removal of Cdc6
R-XTR-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-XTR-69563 p53-Dependent G1 DNA Damage Response
R-XTR-69656 Cyclin A:Cdk2-associated events at S phase entry

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin A1Imported
Gene namesi
Name:ccna1Imported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-922387 ccna1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF7EN95

Expressioni

Gene expression databases

BgeeiENSXETG00000013224

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000028951

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini205 – 236Cyclin N-terminalInterPro annotationAdd BLAST32

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0654 Eukaryota
COG5024 LUCA
GeneTreeiENSGT00760000118939
InParanoidiF7EN95
OMAiAEIRHRP
OrthoDBiEOG091G090I
TreeFamiTF101002

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR039361 Cyclin
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PANTHERiPTHR10177 PTHR10177, 1 hit
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
PROSITEiView protein in PROSITE
PS00292 CYCLINS, 1 hit

Sequencei

Sequence statusi: Complete.

F7EN95-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
SGRCTAASNH RPRCSAATTF LLRIKSPALL GVEVQSNLLP PRVSQRTVLG
60 70 80 90 100
VISDNDQQKR SVGQGGAPAK CLPGIENVLP FAGKILPTNP ALVAPKPIFT
110 120 130 140 150
VYVDEPEEPT ETYSIEEDCP TLDEVDSNIV KQNIHLLLDL SAASPMVVDT
160 170 180 190 200
SLQASPEDDS ITDPDAVAVS EYIDEIHQYL REAELKHRPK AYYMRKQPDI
210 220 230 240 250
TSAMRTILVD WLTEVGEEYK LRTETLYLAV NYLDRFLSCM SVLRGKLQLV
260 270 280 290 300
GTAAILLASK YEEIYPPDVD EFVYITDDTY SKKQLLRMEH LLLKVLAFDL
310 320 330 340 350
TVPTISQFLL QYLQRRAVSV KTEHLAMYLA ELSLLDVEPF LKYVPSITAA
360 370 380 390 400
AAYCLANYAL NKVFWPETLE TFTGYTLSEI TPCLSDLHQA SLRAPFQAQQ
410 420
AIREKYKTPK YMQVSLLEMP AVLPLN
Length:426
Mass (Da):47,721
Last modified:July 27, 2011 - v1
Checksum:i18837C5DABC38D8F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01074245 Genomic DNA No translation available.
AAMC01074246 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSXETT00000028951; ENSXETP00000028951; ENSXETG00000013224

Similar proteinsi

Entry informationi

Entry nameiF7EN95_XENTR
AccessioniPrimary (citable) accession number: F7EN95
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: July 18, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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