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Entry version 39 (05 Jun 2019)
Sequence version 2 (30 Nov 2016)
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Protein
Submitted name:

Uncharacterized protein

Gene

LCOR

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LCORImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacaca mulatta (Rhesus macaque)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9544 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006718 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 9

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMMUG00000010427 Expressed in 13 organ(s), highest expression level in rectum

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
F7EFY1 baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9544.ENSMMUP00000035753

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni137 – 176DisorderedSequence analysisAdd BLAST40
Regioni195 – 251DisorderedSequence analysisAdd BLAST57
Regioni337 – 357DisorderedSequence analysisAdd BLAST21
Regioni481 – 518DisorderedSequence analysisAdd BLAST38
Regioni676 – 1034DisorderedSequence analysisAdd BLAST359
Regioni1079 – 1212DisorderedSequence analysisAdd BLAST134
Regioni1388 – 1431DisorderedSequence analysisAdd BLAST44
Regioni1492 – 1681DisorderedSequence analysisAdd BLAST190

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili83 – 103Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi481 – 500PolarSequence analysisAdd BLAST20
Compositional biasi681 – 708PolyampholyteSequence analysisAdd BLAST28
Compositional biasi723 – 740PolarSequence analysisAdd BLAST18
Compositional biasi820 – 838PolarSequence analysisAdd BLAST19
Compositional biasi874 – 888PolarSequence analysisAdd BLAST15
Compositional biasi893 – 938PolyampholyteSequence analysisAdd BLAST46
Compositional biasi942 – 969PolarSequence analysisAdd BLAST28
Compositional biasi999 – 1026PolyampholyteSequence analysisAdd BLAST28
Compositional biasi1079 – 1128PolyampholyteSequence analysisAdd BLAST50
Compositional biasi1129 – 1147PolarSequence analysisAdd BLAST19
Compositional biasi1157 – 1198PolarSequence analysisAdd BLAST42
Compositional biasi1499 – 1531PolyampholyteSequence analysisAdd BLAST33
Compositional biasi1539 – 1604PolyampholyteSequence analysisAdd BLAST66
Compositional biasi1605 – 1655PolarSequence analysisAdd BLAST51

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHUE Eukaryota
ENOG4111MRK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154965

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F7EFY1

TreeFam database of animal gene trees

More...
TreeFami
TF332137

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028104 DUF4553

The PANTHER Classification System

More...
PANTHERi
PTHR14931 PTHR14931, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF15090 DUF4553, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F7EFY1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQILLSGVHS AAISCGFESI LEGLFGPALL KDLSLFKDCE PESISDWTFD
60 70 80 90 100
ENCLFCCLRR DKVKGHLVGL DEPDSGAGQE ALLKQEQAKI IRFERQAEEF
110 120 130 140 150
LNAVFYRKDS PWVSDPNIPL VAREIMQRMI QQFAAEYTSK NSSTQDPSQP
160 170 180 190 200
NSTKNQSLPK ASPVTTSPTA ATTQNPVLSK LLMADQDSPL DLTVRKSQSE
210 220 230 240 250
PSEQDGVLDL STKKSPCAGS TSLSHSPGCS STQGNGENST EAKAVDSNNQ
260 270 280 290 300
SKSPLEKFMV KLCTHHQKQF IRVLNDLYTE SQPGTEDLQP SDSGAMDVST
310 320 330 340 350
CNAGCAQLST KHKEKDALCL DMKSSASVDL FVDSSDSHSP LHLTEQTPKE
360 370 380 390 400
PPPEINPVDG RENALTVVQK DSSELPTTKP NSVNSSSVDS FTPGYLTASN
410 420 430 440 450
SSSVNFHHIP KNLEGQTTGQ EQDTNVNICE DGKDHMQSSA LVESLITVKM
460 470 480 490 500
AAENSEEGNT CIIPQRNSFR ALSEEAWDSG FMGNSSRTAD KENTLQCPKT
510 520 530 540 550
PMRQDLEANE QDARPKQENH LHSLGRNKVG YHLHPSDKGQ FDHSKDGWLG
560 570 580 590 600
PGPMPTVHKA ANGHSRTKMI STSIKTARKS KRASGLRIND YDNQCDVVYI
610 620 630 640 650
SQPITECHFE NQKSILSSRK TARKSTRGYF FNGDCCELPT VRTLARNLHS
660 670 680 690 700
QEKASCSALA SEAVFTPKQT LTISAPRHTV DVQLPREDNP EEPSKEITSH
710 720 730 740 750
EEGGGDVSPG KEPQEPEVCP TKMKPSLSSS PRSEETTASS LGWPLPAHLP
760 770 780 790 800
EEDLPEGGPT VSAPTASGMS SEHDQPPLAL LDTEEMSVPQ DCHPLPSTES
810 820 830 840 850
FSGGGSEDVI SRPHSPPETV SREESPQCSE NQSSPVDLEP PMSLGKAEDD
860 870 880 890 900
QSISAEVESG DTQELDVNPL LKESRTFTDE NPSGTEESEV AGGTGKLEGE
910 920 930 940 950
DDDVKCLSEK DTCDPSIDSL EENLDKKKKG KKFPEASDRC LRSQLLDSSS
960 970 980 990 1000
ADRCLRNQSS NSSSACLEIK VPKNPSAKRS KKEGHPGGTT PEGLPPDSFH
1010 1020 1030 1040 1050
TEALEDTEKP SVSEHSPEKD AEQEGEGGGI ITRQTLKNML VKEVKELGGE
1060 1070 1080 1090 1100
IFPSRDPITT AGQPLPGERL EIYVQSKMDE KNAHIPSESI PCKRDPEQAK
1110 1120 1130 1140 1150
EEPGHIPTQH VEKAVNEVDN ENTQQKDDDS DAPCSSLGLS SSGSGDAARP
1160 1170 1180 1190 1200
PKSVPRPKRL TSSTYNLRHT HSLGSLDASK VTSEKEAAQV SPTMPKENGA
1210 1220 1230 1240 1250
SESGDPLDED DVDTVVDEQP KFMEWCAEEE NQELIANFNA QYMKVQKGWI
1260 1270 1280 1290 1300
QLEKEGQPTP RARNKSDKLK EIWKSKKRSR KCRGSLEGQK FSPVQMLFMT
1310 1320 1330 1340 1350
NFKLSNVCKW FLETTETRSL VIVKKLNTRL PGDVPPVKHP LQKYSPSSLY
1360 1370 1380 1390 1400
PSSLQAERLK KHLKKFPGAT PARNNWKTQK LWAKFRENPD QVEPEDGSDV
1410 1420 1430 1440 1450
SPSPNSEDSI EEVKEDKNSH PPANLPTPAS TRILRKYSNI RGKLRAQQRL
1460 1470 1480 1490 1500
IKNEKMECPD GLAVESKPSR KSVCINPLMS PKLALQVDVD GFPVKPKSTE
1510 1520 1530 1540 1550
GMKGRKGKQV SEILPKAEVQ SKRKRTEGSS PPDGKNKGPA VKASKEKHAD
1560 1570 1580 1590 1600
GVTKTPAAKR PAARDRSSQP PKKTSLKENK VKIPKKSAGK SCPPSRKEKE
1610 1620 1630 1640 1650
NTNKRPSQSI ASETLTKPAK QKGASESSSR PQKATNRKQS SGKTRARPST
1660 1670 1680
KTPESSAAQR KRKLKAKLDS SHGKRRRLDA K
Length:1,681
Mass (Da):184,053
Last modified:November 30, 2016 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0B367C563BCEE8CA
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F7CXL8F7CXL8_MACMU
Uncharacterized protein
LCOR
406Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5QGE4A0A1D5QGE4_MACMU
Uncharacterized protein
LCOR
396Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1D5QFL6A0A1D5QFL6_MACMU
Uncharacterized protein
LCOR
521Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
JSUE03044072 Genomic DNA No translation available.
JSUE03044073 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_015003330.1, XM_015147844.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMMUT00000014590; ENSMMUP00000035753; ENSMMUG00000010427

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
705646

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03044072 Genomic DNA No translation available.
JSUE03044073 Genomic DNA No translation available.
RefSeqiXP_015003330.1, XM_015147844.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000035753

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMMUT00000014590; ENSMMUP00000035753; ENSMMUG00000010427
GeneIDi705646

Phylogenomic databases

eggNOGiENOG410IHUE Eukaryota
ENOG4111MRK LUCA
GeneTreeiENSGT00940000154965
InParanoidiF7EFY1
TreeFamiTF332137

Gene expression databases

BgeeiENSMMUG00000010427 Expressed in 13 organ(s), highest expression level in rectum
ExpressionAtlasiF7EFY1 baseline

Family and domain databases

InterProiView protein in InterPro
IPR028104 DUF4553
PANTHERiPTHR14931 PTHR14931, 1 hit
PfamiView protein in Pfam
PF15090 DUF4553, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7EFY1_MACMU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7EFY1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: June 5, 2019
This is version 39 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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