UniProtKB - F7ECU3 (F7ECU3_MACMU)
Protein
Submitted name:
Dystrophin related protein 2
Gene
DRP2
Organism
Macaca mulatta (Rhesus macaque)
Status
Functioni
GO - Molecular functioni
- zinc ion binding Source: InterPro
GO - Biological processi
- synaptic signaling Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Dystrophin related protein 2ImportedSubmitted name: Dystrophin-related protein 2 isoform 1Imported |
Gene namesi | Name:DRP2Imported |
Organismi | Macaca mulatta (Rhesus macaque)Imported |
Taxonomic identifieri | 9544 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:71994, DRP2 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: GO_Central
Other locations
- synapse Source: UniProtKB-KW
Keywords - Cellular componenti
Cell junction, Cell membraneARBA annotation, Membrane, SynapseARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMMUG00000021579, Expressed in primary visual cortex and 14 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 352 – 385 | WWInterPro annotationAdd BLAST | 34 | |
Domaini | 604 – 651 | ZZ-typeInterPro annotationAdd BLAST | 48 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 877 – 923 | DisorderedSequence analysisAdd BLAST | 47 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 782 – 809 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 832 – 876 | Sequence analysisAdd BLAST | 45 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 879 – 904 | PolarSequence analysisAdd BLAST | 26 |
Keywords - Domaini
Coiled coilSequence analysis, RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
eggNOGi | KOG4286, Eukaryota |
GeneTreei | ENSGT00940000153467 |
HOGENOMi | CLU_001187_0_0_1 |
OrthoDBi | 72477at2759 |
TreeFami | TF337303 |
Family and domain databases
CDDi | cd00201, WW, 1 hit |
Gene3Di | 3.30.60.90, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR015153, EF-hand_dom_typ1 IPR015154, EF-hand_dom_typ2 IPR018159, Spectrin/alpha-actinin IPR002017, Spectrin_repeat IPR001202, WW_dom IPR036020, WW_dom_sf IPR000433, Znf_ZZ IPR043145, Znf_ZZ_sf |
Pfami | View protein in Pfam PF09068, EF-hand_2, 1 hit PF09069, EF-hand_3, 1 hit PF00435, Spectrin, 1 hit PF00397, WW, 1 hit PF00569, ZZ, 1 hit |
SMARTi | View protein in SMART SM00150, SPEC, 2 hits SM00456, WW, 1 hit SM00291, ZnF_ZZ, 1 hit |
SUPFAMi | SSF47473, SSF47473, 2 hits SSF51045, SSF51045, 1 hit |
PROSITEi | View protein in PROSITE PS01159, WW_DOMAIN_1, 1 hit PS50020, WW_DOMAIN_2, 1 hit PS01357, ZF_ZZ_1, 1 hit PS50135, ZF_ZZ_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F7ECU3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQPMVMQGCP YTLPRCHDWQ AADQFHHSSS LRSTCPHPQV RAAVTSPAPP
60 70 80 90 100
QDGAGVPCLS LKLLNGSVGA SGPLEPPAMN LCWNEIKKKS HNLRARLEAF
110 120 130 140 150
SDHSGKLQLP LQEIIDWLSQ KDEELSAQLP LQGDVALVQQ EKETHAAFME
160 170 180 190 200
EVKSRGPYIY SVLESAQAFL SQHPFEELEE PHSESKDTSP KRRIQNLSRF
210 220 230 240 250
VWKQATVASE LWEKLTARCV DQHRHIERTL EQLLEIQGAM EELSTTLSQA
260 270 280 290 300
EGVRATWEPI GDLFIDSLPE HIQAIKLFKE EFSPMKDGVK LVNDLAHQLA
310 320 330 340 350
ISDVHLSMEN SHALEQINVR WKQLQASVSE RLKQLQDAHR DFGPGSQHFL
360 370 380 390 400
SSSVQVPWER AISPNKVPYY INHQAQTTCW DHPKMTELYQ TLADLNNIKF
410 420 430 440 450
SAYRTAMKLR RVQKALRLDL VTLTTALEIF NEHDLQASEH VMDVVEVIHC
460 470 480 490 500
LTALYERLEE ERGILVNVPL CVDMSLNWLL NVFDSGRSGK MRALSFKTGI
510 520 530 540 550
ACLCGTEVKE KLQYLFSQVA NSGSQCDQRH LGVLLHEAIQ VPRQLGEVAA
560 570 580 590 600
FGGSNVEPSV RSCFRFSTGK PVIEASQFLE WVNLEPQSMV WLAVLHRVTI
610 620 630 640 650
AEQVKHQTKC SICRQCPIKG FRYRSLKQFN VDICQTCFLT GRASKGNKLH
660 670 680 690 700
YPIMEYYTPT TSSENMRDFA TTLKNKFRSK HYFSKHPQRG YLPVQSVLEA
710 720 730 740 750
DYSETPASSP MLPHADTHSR IEHFASRLAE MESQNCSFFN DSLSPDDSID
760 770 780 790 800
EDQYLLRHSS PITDREPAFG QQAPCSVATE SKGELQKILA HLEDENRILQ
810 820 830 840 850
GELRRLKWQH EEAAEAPTLA DGSTEAAPDH RNEELLAEAR ILRQHKSRLE
860 870 880 890 900
TRMQILEDHN KQLESQLQRL RELLLQPPTE SDGSGSAGSS LASSPQQSEG
910 920 930 940 950
SHPREKGQTT PDTEAADDVG SKSQDVSLCL EDIMEKLRHA FPSVRSSDVT
ANTLLAS
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketF7ECT8 | F7ECT8_MACMU | Dystrophin related protein 2 | DRP2 | 935 | Annotation score: | ||
A0A5F7ZNZ6 | A0A5F7ZNZ6_MACMU | Dystrophin related protein 2 | DRP2 | 879 | Annotation score: | ||
A0A5F8A0T9 | A0A5F8A0T9_MACMU | Dystrophin related protein 2 | DRP2 | 959 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JV565013 mRNA Translation: AFJ70348.1 |
RefSeqi | NP_001253144.1, NM_001266215.2 XP_014983265.1, XM_015127779.1 |
Genome annotation databases
Ensembli | ENSMMUT00000030367; ENSMMUP00000028417; ENSMMUG00000021579 |
GeneIDi | 702655 |
KEGGi | mcc:702655 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | JV565013 mRNA Translation: AFJ70348.1 |
RefSeqi | NP_001253144.1, NM_001266215.2 XP_014983265.1, XM_015127779.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9544.ENSMMUP00000028418 |
Genome annotation databases
Ensembli | ENSMMUT00000030367; ENSMMUP00000028417; ENSMMUG00000021579 |
GeneIDi | 702655 |
KEGGi | mcc:702655 |
Organism-specific databases
CTDi | 1821 |
VGNCi | VGNC:71994, DRP2 |
Phylogenomic databases
eggNOGi | KOG4286, Eukaryota |
GeneTreei | ENSGT00940000153467 |
HOGENOMi | CLU_001187_0_0_1 |
OrthoDBi | 72477at2759 |
TreeFami | TF337303 |
Gene expression databases
Bgeei | ENSMMUG00000021579, Expressed in primary visual cortex and 14 other tissues |
Family and domain databases
CDDi | cd00201, WW, 1 hit |
Gene3Di | 3.30.60.90, 1 hit |
InterProi | View protein in InterPro IPR011992, EF-hand-dom_pair IPR015153, EF-hand_dom_typ1 IPR015154, EF-hand_dom_typ2 IPR018159, Spectrin/alpha-actinin IPR002017, Spectrin_repeat IPR001202, WW_dom IPR036020, WW_dom_sf IPR000433, Znf_ZZ IPR043145, Znf_ZZ_sf |
Pfami | View protein in Pfam PF09068, EF-hand_2, 1 hit PF09069, EF-hand_3, 1 hit PF00435, Spectrin, 1 hit PF00397, WW, 1 hit PF00569, ZZ, 1 hit |
SMARTi | View protein in SMART SM00150, SPEC, 2 hits SM00456, WW, 1 hit SM00291, ZnF_ZZ, 1 hit |
SUPFAMi | SSF47473, SSF47473, 2 hits SSF51045, SSF51045, 1 hit |
PROSITEi | View protein in PROSITE PS01159, WW_DOMAIN_1, 1 hit PS50020, WW_DOMAIN_2, 1 hit PS01357, ZF_ZZ_1, 1 hit PS50135, ZF_ZZ_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7ECU3_MACMU | |
Accessioni | F7ECU3Primary (citable) accession number: F7ECU3 Secondary accession number(s): G7NSG8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | November 30, 2016 | |
Last modified: | October 7, 2020 | |
This is version 58 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |