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Entry version 48 (02 Jun 2021)
Sequence version 4 (02 Jun 2021)
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Protein
Submitted name:

RPGR-interacting protein 1

Gene

rpgrip1

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RPGR-interacting protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rpgrip1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-1007974, rpgrip1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, CiliumARBA annotation

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F7E381

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000017215, Expressed in testis and 5 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000037502

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RPGRIP1 family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG502R3GU, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_002108_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F7E381

Identification of Orthologs from Complete Genome Data

More...
OMAi
LCIQQIV

TreeFam database of animal gene trees

More...
TreeFami
TF328883

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021656, C2-C2_1
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR031134, RPGRIP1
IPR041091, RPGRIP1_C
IPR031139, RPGRIP1_fam

The PANTHER Classification System

More...
PANTHERi
PTHR14240, PTHR14240, 1 hit
PTHR14240:SF3, PTHR14240:SF3, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 1 hit
PF11618, C2-C2_1, 1 hit
PF18111, RPGR1_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

F7E381-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSVLLLDETC SDLPVRDTDC KPAVFKAIQD VIAGPYSRKQ HGQRTMKVKE
60 70 80 90 100
KDLKTHRRVS HISREELEDN FIRIHEENIL LKDHARKMED KIKRMGTKLL
110 120 130 140 150
RVTSDLAQTG KSFGARHDGR DLEAEETIED LQDRVRDLEH KNESLRHKLV
160 170 180 190 200
TYKQRLQVQN GCRHCPYSTV AARTDSGVRK NIVLPHNIKR GLRVQSLEAR
210 220 230 240 250
PPQVCQVQAC GETLSDEARE EIERLFNLIE SQNNRVDDKS TVVLKSMESM
260 270 280 290 300
RSKDAEMMLY LQKMQQAENQ RNSIQENVML IRLQKELREK NTTLCALKEQ
310 320 330 340 350
FHQLKESYET ELQQNQKSLT LSHEAVLTQL EDLTSQLKAE RAKVVAMEIE
360 370 380 390 400
QQSVLNLQRS LQEFQERVTD LEKENALLKE NYDSLLKSSL NEDNISSKQA
410 420 430 440 450
IESELRGKIS LLEEQIHHHI SDKTLNKEHL QHEREQNEHL KKEVSQLHMQ
460 470 480 490 500
LLEKIQEVKS YQEKVSAILS SSFNNTVPEQ LGVTLPRTST PRPEGSYQMR
510 520 530 540 550
ELEAVMDRWF DDRERRKKTD EKKHQMGCED EQRQSEDSEK RREEEEQKKA
560 570 580 590 600
EEAEKQRQIC RMDADHAETI LELEKTREML FLQHEINNDY QEELKTLRLK
610 620 630 640 650
SESESRDKEE RKCHYEARIM KYRARIQTLE AQLKDIAYGT FPSRYESESP
660 670 680 690 700
DVDMSPVPSL QRGETLFEVH IGAVCFTPRG LREVSDSQPH TFCVYSLYDY
710 720 730 740 750
ETHATPVVTG TSPQYSFTSH YAVTPDAEFL RFLRVGTLTV ELYQALGGEH
760 770 780 790 800
RELARGRIKL EATLQSTEKI HGAVTLTDVS GEDIGELDYW ICLHGSVSQT
810 820 830 840 850
QRVHKQSNKA RSYLSAGRLC RSQKSLASPF STGPQNELTI RIWGCRSLKV
860 870 880 890 900
GYLGYQPSPY TMYRFYHHPD HSTAIIPCSN NPQFGDEFVY QLQITNDLER
910 920 930 940 950
YLQKECLYVY VFDDEDMQPG VYLGRAEVPL VRLAQGDNIQ GDFALLDPCG
960 970 980 990 1000
KCSGSIQISM EWKFSYKTTS YQSTQEIPLS QPSVASKVNM TRAKQFKTRK
1010 1020 1030 1040 1050
AEEDQLDDIT SSKRGRKDFP STSNQNPSAF QKSDLLPAGY KSNGLDTQQE
1060 1070 1080 1090 1100
KGVQALKCAQ DNMEEHMEEN GISGELTADA NDQQSTDNED DIILVVKPSV
1110 1120 1130 1140 1150
PEKPPSSMIR VEIMSLTLNP YSEVMGDSAV QRLFVEFRFA GVPPEETETP
1160 1170 1180 1190 1200
VSLRKPNQGE ELYYHFSKVI HLDGSEHAER RDFLYMLLEG SDSNGDIVRL
1210 1220 1230 1240 1250
KFTVVSDPIN EDEEECCDVG YAYMDLRPLL RRAEDKAEET LQVLDVADQE
1260 1270
QVIGALRVAI EAKEAARTVH RIKRAKEIR
Length:1,279
Mass (Da):147,207
Last modified:June 2, 2021 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF6D52FC40405AC06
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A803JVI9A0A803JVI9_XENTR
RPGR-interacting protein 1
rpgrip1
1,271Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_012826764.1, XM_012971310.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000037502; ENSXETP00000037502; ENSXETG00000017215

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100497908

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xtr:100497908

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_012826764.1, XM_012971310.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000037502

Proteomic databases

PaxDbiF7E381

Genome annotation databases

EnsembliENSXETT00000037502; ENSXETP00000037502; ENSXETG00000017215
GeneIDi100497908
KEGGixtr:100497908

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
57096
XenbaseiXB-GENE-1007974, rpgrip1

Phylogenomic databases

eggNOGiENOG502R3GU, Eukaryota
HOGENOMiCLU_002108_0_0_1
InParanoidiF7E381
OMAiLCIQQIV
TreeFamiTF328883

Gene expression databases

BgeeiENSXETG00000017215, Expressed in testis and 5 other tissues

Family and domain databases

Gene3Di2.60.40.150, 3 hits
InterProiView protein in InterPro
IPR021656, C2-C2_1
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR031134, RPGRIP1
IPR041091, RPGRIP1_C
IPR031139, RPGRIP1_fam
PANTHERiPTHR14240, PTHR14240, 1 hit
PTHR14240:SF3, PTHR14240:SF3, 1 hit
PfamiView protein in Pfam
PF00168, C2, 1 hit
PF11618, C2-C2_1, 1 hit
PF18111, RPGR1_C, 1 hit
SMARTiView protein in SMART
SM00239, C2, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7E381_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7E381
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: June 2, 2021
Last modified: June 2, 2021
This is version 48 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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