UniProtKB - F7E2N4 (F7E2N4_HORSE)
Protein
Submitted name:
Uncharacterized protein
Gene
N/A
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- ubiquitin protein ligase activity Source: GO_Central
GO - Biological processi
- innate immune response Source: GO_Central
- protein ubiquitination Source: GO_Central
- regulation of gene expression Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Uncharacterized proteinImported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Subcellular locationi
Other locations
- cytoplasm Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSECAG00000019401, Expressed in testis and 1 other tissue |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 23 – 64 | RING-typeInterPro annotationAdd BLAST | 42 | |
Domaini | 276 – 458 | B30.2/SPRYInterPro annotationAdd BLAST | 183 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 199 – 226 | Sequence analysisAdd BLAST | 28 |
Keywords - Domaini
Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000160005 |
HOGENOMi | CLU_013137_0_3_1 |
InParanoidi | F7E2N4 |
TreeFami | TF338674 |
Family and domain databases
Gene3Di | 2.60.120.920, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR003879, Butyrophylin_SPRY IPR013320, ConA-like_dom_sf IPR003877, SPRY_dom IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD IPR017907, Znf_RING_CS |
Pfami | View protein in Pfam PF00622, SPRY, 1 hit |
PRINTSi | PR01407, BUTYPHLNCDUF |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit PS00518, ZF_RING_1, 1 hit PS50089, ZF_RING_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F7E2N4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEKSIHSTQR NMDSNVFQNQ FTCSMCMNYF IDPVTIGCGH SFCMPCLCIC
60 70 80 90 100
WEGAQHPPRC PVCREISHQT NFKTNIILRT QVFLARRARP YQFLSSAEQM
110 120 130 140 150
CEIHLKTKNF FCEVIKDFLC LLCCKSKEHV AHRHCSIDWI AEEYRQELLK
160 170 180 190 200
QMRFVWEKTQ ENQRNRNREI RKIRTWEGYV TLRRKMIRTE YQKVCQLLYK
210 220 230 240 250
EEKHHLERIE KESREILQQL KESEDSMDLK GKLLRGMYEE LKEMCHKPDM
260 270 280 290 300
ELLRHFENIL KRSESVQLHM PQPVDSQLSS WPITGLIDRL NRSQVYISLD
310 320 330 340 350
NEIVTGRIPL FENLRCLLFG ADHPEVANNP TRSKYFFAWG TQSFTSGQHY
360 370 380 390 400
WEVYVGNCWN WVIGFCNDSW TMRNDMVVDS EGIFLLFCVK EDNGCSLFTS
410 420 430 440 450
SPLLPQYVER PLGYVGVFLD YECGVVSFVN VANSSLICSS LSCSFSSPLK
PFLCSGLP
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PLJ9 | A0A5F5PLJ9_HORSE | RING-type domain-containing protein | 222 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000020745; ENSECAP00000017040; ENSECAG00000019401 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F7E2N4 |
Genome annotation databases
Ensembli | ENSECAT00000020745; ENSECAP00000017040; ENSECAG00000019401 |
Phylogenomic databases
GeneTreei | ENSGT00940000160005 |
HOGENOMi | CLU_013137_0_3_1 |
InParanoidi | F7E2N4 |
TreeFami | TF338674 |
Gene expression databases
Bgeei | ENSECAG00000019401, Expressed in testis and 1 other tissue |
Family and domain databases
Gene3Di | 2.60.120.920, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR001870, B30.2/SPRY IPR043136, B30.2/SPRY_sf IPR003879, Butyrophylin_SPRY IPR013320, ConA-like_dom_sf IPR003877, SPRY_dom IPR001841, Znf_RING IPR013083, Znf_RING/FYVE/PHD IPR017907, Znf_RING_CS |
Pfami | View protein in Pfam PF00622, SPRY, 1 hit |
PRINTSi | PR01407, BUTYPHLNCDUF |
SMARTi | View protein in SMART SM00184, RING, 1 hit |
SUPFAMi | SSF49899, SSF49899, 1 hit |
PROSITEi | View protein in PROSITE PS50188, B302_SPRY, 1 hit PS00518, ZF_RING_1, 1 hit PS50089, ZF_RING_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7E2N4_HORSE | |
Accessioni | F7E2N4Primary (citable) accession number: F7E2N4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | October 7, 2020 | |
This is version 58 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |