UniProtKB - F7DHF7 (F7DHF7_HORSE)
Protein
Submitted name:
RNA polymerase II associated protein 3
Gene
RPAP3
Organism
Equus caballus (Horse)
Status
Names & Taxonomyi
Protein namesi | Submitted name: RNA polymerase II associated protein 3Imported |
Gene namesi | Name:RPAP3Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:22514, RPAP3 |
Subcellular locationi
Cytosol
- cytosol Source: Ensembl
Other locations
- R2TP complex Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSECAG00000020050, Expressed in brainstem and 22 other tissues |
ExpressionAtlasi | F7DHF7, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 133 – 382 | TPR_REGIONInterPro annotationAdd BLAST | 250 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 37 – 82 | DisorderedSequence analysisAdd BLAST | 46 | |
Regioni | 106 – 128 | DisorderedSequence analysisAdd BLAST | 23 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 210 – 230 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000156749 |
HOGENOMi | CLU_023272_1_0_1 |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits |
InterProi | View protein in InterPro IPR025986, RPAP3-like_C IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR001440, TPR_1 IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF13877, RPAP3_C, 1 hit PF00515, TPR_1, 2 hits PF13176, TPR_7, 1 hit PF13181, TPR_8, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 6 hits |
SUPFAMi | SSF48452, SSF48452, 2 hits |
PROSITEi | View protein in PROSITE PS50005, TPR, 5 hits PS50293, TPR_REGION, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
F7DHF7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MTSTNKAIEL QLQVKQNAEE LQDFMRDLEN WEKDIKQKDM ELRRQSGVPE
60 70 80 90 100
ENLPPIRNGN FRKKKKGKAK ETSKKTKDEN TKNRIKSYDY EAWAKLDVDS
110 120 130 140 150
ILDELDKEES THDSVSQESE SEEDGIHVDS QKALALKEKG NKYFKQGKYD
160 170 180 190 200
EAIECYTKGM DADPYNPVLP TNRASAYFRM KKFAVAESDC NLAIALNRSY
210 220 230 240 250
TKAYARRGAA RFALQKLEDA KKDYEKVLEL EPNNFEATNE LRKINQALTS
260 270 280 290 300
KENSCPKEAD IMIKSTEGER KTEEQRNKLQ AISEKDRGNG FFKEGKYERA
310 320 330 340 350
IECYTRGIAA DGANALLPAN RAMAYLKIQK YEEAEKDCTQ AIFLDGSYSK
360 370 380 390 400
AFARRGTART FLGKLNEAKQ DFETVLLLEP GNKQAATELA KIKKELIDKG
410 420 430 440 450
HWDDVFLDST QRQNVIKPID NPPHLGSTKP LKKVTIEETG NLIETVEVPE
460 470 480 490 500
SSTVAAALES DPTNLAGVIA TTGAAAKNSS QDDLLPTSDF PKAKVLKIEE
510 520 530 540 550
ISDASGPQPQ INLKQDVCQS FSEKISIEVD KTPAQFTTTV LPQVPANSFQ
560 570 580 590 600
LESDFRQLKN SPEMLYQYLK QIEPSLYPTL FQKNLDPDVF NQIIKILHDF
610 620 630 640 650
YIEKEKPSLI FEILQRLSEL KRFDMAVMFM SEPERKSPEF SSTTWPKPMK
660 670 680 690 700
QKPGTLLSQS LQQFTALHED GCYLRRLRIS VCSLPTGTWL PLLLGLLRKS
R
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PUK6 | A0A5F5PUK6_HORSE | RNA polymerase II associated protei... | RPAP3 | 630 | Annotation score: | ||
F7E0B9 | F7E0B9_HORSE | RNA polymerase II associated protei... | RPAP3 | 664 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000021515; ENSECAP00000017723; ENSECAG00000020050 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSECAT00000021515; ENSECAP00000017723; ENSECAG00000020050 |
Organism-specific databases
VGNCi | VGNC:22514, RPAP3 |
Phylogenomic databases
GeneTreei | ENSGT00940000156749 |
HOGENOMi | CLU_023272_1_0_1 |
Gene expression databases
Bgeei | ENSECAG00000020050, Expressed in brainstem and 22 other tissues |
ExpressionAtlasi | F7DHF7, baseline |
Family and domain databases
Gene3Di | 1.25.40.10, 2 hits |
InterProi | View protein in InterPro IPR025986, RPAP3-like_C IPR013026, TPR-contain_dom IPR011990, TPR-like_helical_dom_sf IPR001440, TPR_1 IPR019734, TPR_repeat |
Pfami | View protein in Pfam PF13877, RPAP3_C, 1 hit PF00515, TPR_1, 2 hits PF13176, TPR_7, 1 hit PF13181, TPR_8, 1 hit |
SMARTi | View protein in SMART SM00028, TPR, 6 hits |
SUPFAMi | SSF48452, SSF48452, 2 hits |
PROSITEi | View protein in PROSITE PS50005, TPR, 5 hits PS50293, TPR_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7DHF7_HORSE | |
Accessioni | F7DHF7Primary (citable) accession number: F7DHF7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | August 12, 2020 | |
This is version 55 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |