UniProtKB - F7DFB9 (F7DFB9_HORSE)
Protein
Submitted name:
Heparan-alpha-glucosaminide N-acetyltransferase
Gene
HGSNAT
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- heparan-alpha-glucosaminide N-acetyltransferase activity Source: InterPro
GO - Biological processi
- lysosomal transport Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Heparan-alpha-glucosaminide N-acetyltransferaseImported |
Gene namesi | Name:HGSNATImported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:18771, HGSNAT |
Subcellular locationi
Lysosome
- lysosomal membrane Source: GO_Central
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 157 – 180 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 241 – 259 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 274 – 295 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 307 – 326 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 346 – 364 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 385 – 405 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 466 – 489 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 496 – 514 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 534 – 553 | HelicalSequence analysisAdd BLAST | 20 | |
Transmembranei | 565 – 582 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 602 – 620 | HelicalSequence analysisAdd BLAST | 19 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSECAG00000019625, Expressed in articular cartilage of joint and 22 other tissues |
ExpressionAtlasi | F7DFB9, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 232 – 354 | DUF1624InterPro annotationAdd BLAST | 123 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 15 – 35 | DisorderedSequence analysisAdd BLAST | 21 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
GeneTreei | ENSGT00390000001491 |
HOGENOMi | CLU_029171_3_2_1 |
InParanoidi | F7DFB9 |
TreeFami | TF324790 |
Family and domain databases
InterProi | View protein in InterPro IPR040208, HGSNAT IPR012429, HGSNAT_cat |
PANTHERi | PTHR31061:SF19, PTHR31061:SF19, 1 hit |
Pfami | View protein in Pfam PF07786, DUF1624, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F7DFB9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MCACTSTCPQ VRGETLEPES AGTQRPCPDA TAHTDKKRHV ELKMDQALLL
60 70 80 90 100
IHNELLRTNL TVYWNSERCY HCLFQVLVNV SQSRRAGEPS IAAVGVSAQH
110 120 130 140 150
GSILQLKATE EEKEVCRLEY KFGEFGNYSL LVKHVQDGVD RIACDVVVNE
160 170 180 190 200
DPVDSNLPVT VAFLIGLALV IAVCFLRFLL SLDDFNNWIS KAINSRETDH
210 220 230 240 250
LINSELGSPS RADALGGDSQ LEAWGPAAAP QRLRCVDTFR GIALIIMVFV
260 270 280 290 300
NYGGGKYWYF KHSSWNGLTV ADLVFPWFVF IMGSSIFLSM TSTLQRGCSK
310 320 330 340 350
FRLLGKIAWR SFLLISLGIV VVNPNYCLGP LSWDKLRIPG VLQRLGVTYF
360 370 380 390 400
VVAVLELLFA KPVPGSGASE RRCSSLRDIL SSWPQWLFIL LLESIWLGLT
410 420 430 440 450
FFLPVPGCPT GYLGPGGIGD LGRYPNCTGG AAGYIDRLLL GEDHLYQHPS
460 470 480 490 500
SAVLYHTEVA YDPEGILGTI NSIVMAFLGV QAGRILLYYK DQTKAILLRF
510 520 530 540 550
TAWSCFLGLI SVALTKVSEN EGSIPINKNL WSISYVTTLS SFAFFILLVL
560 570 580 590 600
YPTVDVKGLW TGTPFFYPGM NSLLVYVGHE VFESYFPFQW KLGDDQSHRE
610 620
HLTQNIVATA LWVLIAYILY KKKIFWKI
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q2I0J2 | A0A3Q2I0J2_HORSE | Heparan-alpha-glucosaminide N-acety... | HGSNAT | 633 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000020823; ENSECAP00000017114; ENSECAG00000019625 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F7DFB9 |
Genome annotation databases
Ensembli | ENSECAT00000020823; ENSECAP00000017114; ENSECAG00000019625 |
Organism-specific databases
VGNCi | VGNC:18771, HGSNAT |
Phylogenomic databases
GeneTreei | ENSGT00390000001491 |
HOGENOMi | CLU_029171_3_2_1 |
InParanoidi | F7DFB9 |
TreeFami | TF324790 |
Gene expression databases
Bgeei | ENSECAG00000019625, Expressed in articular cartilage of joint and 22 other tissues |
ExpressionAtlasi | F7DFB9, baseline |
Family and domain databases
InterProi | View protein in InterPro IPR040208, HGSNAT IPR012429, HGSNAT_cat |
PANTHERi | PTHR31061:SF19, PTHR31061:SF19, 1 hit |
Pfami | View protein in Pfam PF07786, DUF1624, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7DFB9_HORSE | |
Accessioni | F7DFB9Primary (citable) accession number: F7DFB9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 43 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |