UniProtKB - F7D6A9 (F7D6A9_MACMU)
Protein
Ubiquitinyl hydrolase 1
Gene
OTUD6A
Organism
Macaca mulatta (Rhesus macaque)
Status
Functioni
Catalytic activityi
- Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).ARBA annotation EC:3.4.19.12
GO - Molecular functioni
- cysteine-type peptidase activity Source: UniProtKB-KW
- thiol-dependent ubiquitin-specific protease activity Source: UniProtKB-EC
GO - Biological processi
- protein K11-linked deubiquitination Source: Ensembl
- protein K27-linked deubiquitination Source: Ensembl
- protein K29-linked deubiquitination Source: Ensembl
- protein K33-linked deubiquitination Source: Ensembl
Keywordsi
Molecular function | Hydrolase, Protease, Thiol proteaseARBA annotation |
Biological process | Ubl conjugation pathwayARBA annotation |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:OTUD6AImported |
Organismi | Macaca mulatta (Rhesus macaque)Imported |
Taxonomic identifieri | 9544 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Cercopithecidae › Cercopithecinae › Macaca |
Proteomesi |
|
Expressioni
Gene expression databases
Bgeei | ENSMMUG00000017757, Expressed in Ammon's horn and 5 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 141 – 275 | OTUInterPro annotationAdd BLAST | 135 |
Phylogenomic databases
GeneTreei | ENSGT00940000163556 |
HOGENOMi | CLU_034963_0_0_1 |
OMAi | QDQLVFS |
OrthoDBi | 1541668at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR003323, OTU_dom IPR038765, Papain-like_cys_pep_sf |
Pfami | View protein in Pfam PF02338, OTU, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS50802, OTU, 1 hit |
i Sequence
Sequence statusi: Complete.
F7D6A9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDDPKSEQQR ILRRHQREKK ELQAQIQSLK NSVPKTDKKK RKQLLQDVAR
60 70 80 90 100
MEAEMAQKHR QELEKFQDDS SVESVVEDLA KMDLENRPPR PSKAQRKRER
110 120 130 140 150
MESQERERQE SIFQAEMSEH LAGFRREEEE KLADILGARG LEMKEIPADG
160 170 180 190 200
HCMYRAIQDQ LVFSVSVEML RCRTASYMQK HVDEFLPFFS NPETGDPFGY
210 220 230 240 250
DDFMIYCDNI VRTAAWGGQL ELRALSHVLK TPIEVIQANS PTLVIGEEYV
260 270 280
KKPIILVYLH YAYSLGEHYN SVRPLEAGAA GGALPRLR
Sequence databases
RefSeqi | NP_001180627.1, NM_001193698.1 |
Genome annotation databases
Ensembli | ENSMMUT00000105557; ENSMMUP00000079662; ENSMMUG00000061393 |
GeneIDi | 694498 |
KEGGi | mcc:694498 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | NP_001180627.1, NM_001193698.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSMMUT00000105557; ENSMMUP00000079662; ENSMMUG00000061393 |
GeneIDi | 694498 |
KEGGi | mcc:694498 |
Organism-specific databases
CTDi | 139562 |
Phylogenomic databases
GeneTreei | ENSGT00940000163556 |
HOGENOMi | CLU_034963_0_0_1 |
OMAi | QDQLVFS |
OrthoDBi | 1541668at2759 |
Gene expression databases
Bgeei | ENSMMUG00000017757, Expressed in Ammon's horn and 5 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR003323, OTU_dom IPR038765, Papain-like_cys_pep_sf |
Pfami | View protein in Pfam PF02338, OTU, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS50802, OTU, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7D6A9_MACMU | |
Accessioni | F7D6A9Primary (citable) accession number: F7D6A9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | July 27, 2011 | |
Last modified: | December 2, 2020 | |
This is version 48 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |