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Entry version 61 (02 Dec 2020)
Sequence version 3 (11 Dec 2019)
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Protein

Non-specific serine/threonine protein kinase

Gene

WNK1

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseARBA annotation (EC:2.7.11.1ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WNK1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:52460, WNK1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F7C849

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000023501, Expressed in brainstem and 23 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini220 – 478Protein kinaseInterPro annotationAdd BLAST259

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 81DisorderedSequence analysisAdd BLAST81
Regioni93 – 202DisorderedSequence analysisAdd BLAST110
Regioni572 – 749DisorderedSequence analysisAdd BLAST178
Regioni1009 – 1091DisorderedSequence analysisAdd BLAST83
Regioni1250 – 1269DisorderedSequence analysisAdd BLAST20
Regioni1427 – 1452DisorderedSequence analysisAdd BLAST26
Regioni1711 – 1733DisorderedSequence analysisAdd BLAST23
Regioni1840 – 1898DisorderedSequence analysisAdd BLAST59
Regioni1967 – 2042DisorderedSequence analysisAdd BLAST76
Regioni2085 – 2169DisorderedSequence analysisAdd BLAST85

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2046 – 2066Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 15PolarSequence analysisAdd BLAST15
Compositional biasi23 – 37PolarSequence analysisAdd BLAST15
Compositional biasi48 – 64PolyampholyteSequence analysisAdd BLAST17
Compositional biasi96 – 116Pro-richSequence analysisAdd BLAST21
Compositional biasi138 – 152Pro-richSequence analysisAdd BLAST15
Compositional biasi572 – 588PolyampholyteSequence analysisAdd BLAST17
Compositional biasi589 – 629PolarSequence analysisAdd BLAST41
Compositional biasi636 – 749PolarSequence analysisAdd BLAST114
Compositional biasi1029 – 1063PolarSequence analysisAdd BLAST35
Compositional biasi1067 – 1087BasicSequence analysisAdd BLAST21
Compositional biasi1711 – 1731PolarSequence analysisAdd BLAST21
Compositional biasi1844 – 1858PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1859 – 1891PolarSequence analysisAdd BLAST33
Compositional biasi2003 – 2035PolarSequence analysisAdd BLAST33
Compositional biasi2106 – 2137PolarSequence analysisAdd BLAST32
Compositional biasi2144 – 2169PolarSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155474

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F7C849

TreeFam database of animal gene trees

More...
TreeFami
TF315363

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR024678, Kinase_OSR1/WNK_CCT
IPR000719, Prot_kinase_dom
IPR008271, Ser/Thr_kinase_AS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12202, OSR1_C, 1 hit
PF00069, Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00220, S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56112, SSF56112, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00108, PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

F7C849-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGAAEKQGS TPSALFLSPP APAPKNGSSS DSSVGEKLGS VGTDAGTGRT
60 70 80 90 100
EEYRRRRHTM DKDSRGAAAT TTTTEHRFFR RSVICDSNAT ALELPGLPLP
110 120 130 140 150
LPPPSVAAPV PQSAPPEPHR EETSTAAAAA PGAQEPPAAA GPGEPPAAAP
160 170 180 190 200
VAAPAPSGTS RDRPGAQPSH EGSKEEPPPA RSGSGGASAK EPQEERSQQQ
210 220 230 240 250
DDIEELETKA VGMSNDGRFL KFDIEIGRGS FKTVYKGLDT ETTVEVAWCE
260 270 280 290 300
LQDRKLTKSE RQRFKEEAEM LKGLQHPNIV RFYDSWESTV KGKKCIVLVT
310 320 330 340 350
ELMTSGTLKT YLKRFKVMKI KVLRSWCRQI LKGLQFLHTR TPPIIHRDLK
360 370 380 390 400
CDNIFITGPT GSVKIGDLGL ATLKRASFAK SVIGTPEFMA PEMYEEKYDE
410 420 430 440 450
SVDVYAFGMC MLEMATSEYP YSECQNAAQI YRRVTSGVKP ASFDKVAIPE
460 470 480 490 500
VKEIIEGCIR QNKDERYSIK DLLNHAFFQE ETGVRVELAE EDDGEKIAIK
510 520 530 540 550
LWLRIEDIKK LKGKYKDNEA IEFSFDLERD VPEDVAQEMV ESGYVCEGDH
560 570 580 590 600
KTMAKAIKDR VSLIKRKREQ RQLVREEQEK RKQEESSLKQ QVEQQSSASQ
610 620 630 640 650
AGIKQLPSAS TSVPAASTTS ASVSTQVEPE EPEADQHQQL QYQQPSISVL
660 670 680 690 700
SDGTIDSGQG SSVFTESRVS SQQTVSYGSQ HEQAHSTGTL PGHTASVVQA
710 720 730 740 750
QSQPHGVYPP SSMQGIQQTA PPQQTVQYSL PQTSTSSETT TAQPVSQPQA
760 770 780 790 800
PQVLPQVSAG KQLPVSQPVP TVQGEPHIPV ATQPSVVPVH SGAHFLPMGQ
810 820 830 840 850
PLPTSLLPQY PVSQIPISTP HVSAAQTGFS SLPITMAAGI NQPLLTLASS
860 870 880 890 900
ATAATIPGGS TVVPSQLPTL LQPVTQLPSQ VHPQLLQPAV QSMGIPANLG
910 920 930 940 950
QAAEVPLPSG DVLYQGFPPR LPPQYPGDSN IAPSSSVASV CIPSTVLSPP
960 970 980 990 1000
MPTEALATPG YFPTVVQPYV ESNILVPVGS IGGQVQVSQP AVSLAQALPT
1010 1020 1030 1040 1050
SSQQAALEST QGVAQVAPPE PIPVAQPQPT QPTTLVSSID SAHSDVASGM
1060 1070 1080 1090 1100
SDGNENVPSS SGRHEGRTTK RHYRKSVRSR SRHEKTSRPK LRILNVSNKG
1110 1120 1130 1140 1150
DRVVECQLET HNRKMVTFKF DLDGDNPEEI ATIMVNNDFI LAIERESFVD
1160 1170 1180 1190 1200
QVREIIEKAD EMLSEDVSVE PEGEQGLESL QGKDDYGFSG SQKLEGEFKQ
1210 1220 1230 1240 1250
PIPSSSMPQQ IGIPTSSLTQ VVHSAGRRFI VSPVPESRLR ESKVFTSETS
1260 1270 1280 1290 1300
DTVAASTSHG TGMNLSHSAS SLSLQQAFSE LRHTQMTEGP STAPPNFSHT
1310 1320 1330 1340 1350
GPTFPVVPPS MTSIAGVPTT AAATPSVSVS ATSCPLNDIS TSVIQSEITV
1360 1370 1380 1390 1400
PTEKGIAGVA TCTGVITSSG LPVPPASESP VLSSVVSSIT IPAVVSISTT
1410 1420 1430 1440 1450
SQSVQAPTSG SIVSSIGTLP SVPVSTTSAS TVGSAAAPGA KPPPVLSQQA
1460 1470 1480 1490 1500
AGSTTGIATL TSVSTTTPFP SIASQPAFQL SSSTSAPTLA ETVVISAHSL
1510 1520 1530 1540 1550
DKTSHSSATG LALSLSASSS SPGAGVSSSI SQPSGVHPLV IQSAVASTPV
1560 1570 1580 1590 1600
LPQAAGPTST PLLPQVPSIP PLVQPVASVP AVQQTLIHSQ PQPALLPNQP
1610 1620 1630 1640 1650
HTHCPEIDAD TQPKAPGIDD IKTLEEKLRS LFSEHSSSGA QHASVSLETS
1660 1670 1680 1690 1700
LVVETTVTPG IPTTAVAPSK LMTSTTSTCL PPTSLPLGTT GLSVIPVVTP
1710 1720 1730 1740 1750
GQVSTPVSYV SAPVSSTPGV KPGTTPSKPS LTKAPVLPVG TELPAGTLPS
1760 1770 1780 1790 1800
DQLPPFPGPS LTQQPLEDLD AQLRRTLSPE TVAVTSAVGP VSVVAPTAVT
1810 1820 1830 1840 1850
EAAAQPQKDV SQVTEGPVLA TTSGTGVFKM GRFQVSVAMD DAQKEGQSKS
1860 1870 1880 1890 1900
EDAKSVHFES STSESSVLSS SSPESTLVKP EPNSVTIHGI SSDVPDSAHK
1910 1920 1930 1940 1950
TPLLAAKSET GQSTKVGRFQ VTTTANKVGR FSVSRTEDKI AEAKKEGPMA
1960 1970 1980 1990 2000
SPPFMDLEQA TLPAVIPKKE KPELSEPSHL NGPSSDLEAA FLSRDVDDGS
2010 2020 2030 2040 2050
GSPHSPHQLS SKSLPVQNLS QSLSNSFNSS YMSSDNESDI EDEDLKLELR
2060 2070 2080 2090 2100
RLREKHLKEI QDLQSRQKHE IESLYTKLGK VPPAVIIPPA APLSGRRRRP
2110 2120 2130 2140 2150
TKSKGSKSSR SSSLGNKSPQ LSGNLSGQSS ASVLHPQQTL HPPGHMPESG
2160 2170 2180 2190 2200
QNQLLQPLKP SPSSDNLYSA FTSDGAISVP SLSAPGQGCA KFNCASEQVT
2210 2220 2230 2240 2250
FKPGGRRTRF LRKMVKKVCP CNQLCRTSST NTVGGTVNSQ AAQAQPPAMT
2260 2270 2280 2290 2300
SSRKGTFTDD LHKLVDNWAR DAMNLSGRRG SKGHMNYEGP GMARKFSAPG
2310 2320 2330 2340 2350
QLCISMTSNL GGSAPISAAS ATSLGHFTKS MCPPQQYGFP APPFGTQWSG
2360 2370 2380 2390
TGGPAPQPLG QFQPVGTASL QNFNISNLQK SISNPPGSNL RTT
Length:2,393
Mass (Da):252,298
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9505819D1C68FAA5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2ID61A0A3Q2ID61_HORSE
Non-specific serine/threonine prote...
WNK1
2,881Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7BY14F7BY14_HORSE
Non-specific serine/threonine prote...
WNK1
2,585Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7C2Q9F7C2Q9_HORSE
Non-specific serine/threonine prote...
WNK1
2,421Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7BX86F7BX86_HORSE
Non-specific serine/threonine prote...
WNK1
2,681Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HGQ1A0A3Q2HGQ1_HORSE
Non-specific serine/threonine prote...
WNK1
2,398Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HSN6A0A3Q2HSN6_HORSE
Non-specific serine/threonine prote...
WNK1
2,795Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HYK6A0A3Q2HYK6_HORSE
Non-specific serine/threonine prote...
WNK1
2,349Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2IC89A0A3Q2IC89_HORSE
Non-specific serine/threonine prote...
WNK1
2,290Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000025398; ENSECAP00000021126; ENSECAG00000023501

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PaxDbiF7C849

Genome annotation databases

EnsembliENSECAT00000025398; ENSECAP00000021126; ENSECAG00000023501

Organism-specific databases

VGNCiVGNC:52460, WNK1

Phylogenomic databases

GeneTreeiENSGT00940000155474
InParanoidiF7C849
TreeFamiTF315363

Gene expression databases

BgeeiENSECAG00000023501, Expressed in brainstem and 23 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR024678, Kinase_OSR1/WNK_CCT
IPR000719, Prot_kinase_dom
IPR008271, Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF12202, OSR1_C, 1 hit
PF00069, Pkinase, 1 hit
SMARTiView protein in SMART
SM00220, S_TKc, 1 hit
SUPFAMiSSF56112, SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00108, PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7C849_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7C849
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: December 2, 2020
This is version 61 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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