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UniProtKB - F7C849 (F7C849_HORSE)

Entry version 61 (02 Dec 2020)
Sequence version 3 (11 Dec 2019)
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Protein

Non-specific serine/threonine protein kinase

Gene

WNK1

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseARBA annotation (EC:2.7.11.1ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:WNK1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...VGNCi		VGNC:52460, WNK1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		F7C849

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSECAG00000023501, Expressed in brainstem and 23 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini220 – 478Protein kinaseInterPro annotationAdd BLAST259

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 81DisorderedSequence analysisAdd BLAST81
Regioni93 – 202DisorderedSequence analysisAdd BLAST110
Regioni572 – 749DisorderedSequence analysisAdd BLAST178
Regioni1009 – 1091DisorderedSequence analysisAdd BLAST83
Regioni1250 – 1269DisorderedSequence analysisAdd BLAST20
Regioni1427 – 1452DisorderedSequence analysisAdd BLAST26
Regioni1711 – 1733DisorderedSequence analysisAdd BLAST23
Regioni1840 – 1898DisorderedSequence analysisAdd BLAST59
Regioni1967 – 2042DisorderedSequence analysisAdd BLAST76
Regioni2085 – 2169DisorderedSequence analysisAdd BLAST85

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2046 – 2066Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 15PolarSequence analysisAdd BLAST15
Compositional biasi23 – 37PolarSequence analysisAdd BLAST15
Compositional biasi48 – 64PolyampholyteSequence analysisAdd BLAST17
Compositional biasi96 – 116Pro-richSequence analysisAdd BLAST21
Compositional biasi138 – 152Pro-richSequence analysisAdd BLAST15
Compositional biasi572 – 588PolyampholyteSequence analysisAdd BLAST17
Compositional biasi589 – 629PolarSequence analysisAdd BLAST41
Compositional biasi636 – 749PolarSequence analysisAdd BLAST114
Compositional biasi1029 – 1063PolarSequence analysisAdd BLAST35
Compositional biasi1067 – 1087BasicSequence analysisAdd BLAST21
Compositional biasi1711 – 1731PolarSequence analysisAdd BLAST21
Compositional biasi1844 – 1858PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1859 – 1891PolarSequence analysisAdd BLAST33
Compositional biasi2003 – 2035PolarSequence analysisAdd BLAST33
Compositional biasi2106 – 2137PolarSequence analysisAdd BLAST32
Compositional biasi2144 – 2169PolarSequence analysisAdd BLAST26

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...GeneTreei		ENSGT00940000155474

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		F7C849

TreeFam database of animal gene trees

More...TreeFami		TF315363

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR024678, Kinase_OSR1/WNK_CCT
IPR000719, Prot_kinase_dom
IPR008271, Ser/Thr_kinase_AS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12202, OSR1_C, 1 hit
PF00069, Pkinase, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00220, S_TKc, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF56112, SSF56112, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00108, PROTEIN_KINASE_ST, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

F7C849-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGAAEKQGS TPSALFLSPP APAPKNGSSS DSSVGEKLGS VGTDAGTGRT 
        60         70         80         90        100
EEYRRRRHTM DKDSRGAAAT TTTTEHRFFR RSVICDSNAT ALELPGLPLP 
       110        120        130        140        150
LPPPSVAAPV PQSAPPEPHR EETSTAAAAA PGAQEPPAAA GPGEPPAAAP 
       160        170        180        190        200
VAAPAPSGTS RDRPGAQPSH EGSKEEPPPA RSGSGGASAK EPQEERSQQQ 
       210        220        230        240        250
DDIEELETKA VGMSNDGRFL KFDIEIGRGS FKTVYKGLDT ETTVEVAWCE 
       260        270        280        290        300
LQDRKLTKSE RQRFKEEAEM LKGLQHPNIV RFYDSWESTV KGKKCIVLVT 
       310        320        330        340        350
ELMTSGTLKT YLKRFKVMKI KVLRSWCRQI LKGLQFLHTR TPPIIHRDLK 
       360        370        380        390        400
CDNIFITGPT GSVKIGDLGL ATLKRASFAK SVIGTPEFMA PEMYEEKYDE 
       410        420        430        440        450
SVDVYAFGMC MLEMATSEYP YSECQNAAQI YRRVTSGVKP ASFDKVAIPE 
       460        470        480        490        500
VKEIIEGCIR QNKDERYSIK DLLNHAFFQE ETGVRVELAE EDDGEKIAIK 
       510        520        530        540        550
LWLRIEDIKK LKGKYKDNEA IEFSFDLERD VPEDVAQEMV ESGYVCEGDH 
       560        570        580        590        600
KTMAKAIKDR VSLIKRKREQ RQLVREEQEK RKQEESSLKQ QVEQQSSASQ 
       610        620        630        640        650
AGIKQLPSAS TSVPAASTTS ASVSTQVEPE EPEADQHQQL QYQQPSISVL 
       660        670        680        690        700
SDGTIDSGQG SSVFTESRVS SQQTVSYGSQ HEQAHSTGTL PGHTASVVQA 
       710        720        730        740        750
QSQPHGVYPP SSMQGIQQTA PPQQTVQYSL PQTSTSSETT TAQPVSQPQA 
       760        770        780        790        800
PQVLPQVSAG KQLPVSQPVP TVQGEPHIPV ATQPSVVPVH SGAHFLPMGQ 
       810        820        830        840        850
PLPTSLLPQY PVSQIPISTP HVSAAQTGFS SLPITMAAGI NQPLLTLASS 
       860        870        880        890        900
ATAATIPGGS TVVPSQLPTL LQPVTQLPSQ VHPQLLQPAV QSMGIPANLG 
       910        920        930        940        950
QAAEVPLPSG DVLYQGFPPR LPPQYPGDSN IAPSSSVASV CIPSTVLSPP 
       960        970        980        990       1000
MPTEALATPG YFPTVVQPYV ESNILVPVGS IGGQVQVSQP AVSLAQALPT 
      1010       1020       1030       1040       1050
SSQQAALEST QGVAQVAPPE PIPVAQPQPT QPTTLVSSID SAHSDVASGM 
      1060       1070       1080       1090       1100
SDGNENVPSS SGRHEGRTTK RHYRKSVRSR SRHEKTSRPK LRILNVSNKG 
      1110       1120       1130       1140       1150
DRVVECQLET HNRKMVTFKF DLDGDNPEEI ATIMVNNDFI LAIERESFVD 
      1160       1170       1180       1190       1200
QVREIIEKAD EMLSEDVSVE PEGEQGLESL QGKDDYGFSG SQKLEGEFKQ 
      1210       1220       1230       1240       1250
PIPSSSMPQQ IGIPTSSLTQ VVHSAGRRFI VSPVPESRLR ESKVFTSETS 
      1260       1270       1280       1290       1300
DTVAASTSHG TGMNLSHSAS SLSLQQAFSE LRHTQMTEGP STAPPNFSHT 
      1310       1320       1330       1340       1350
GPTFPVVPPS MTSIAGVPTT AAATPSVSVS ATSCPLNDIS TSVIQSEITV 
      1360       1370       1380       1390       1400
PTEKGIAGVA TCTGVITSSG LPVPPASESP VLSSVVSSIT IPAVVSISTT 
      1410       1420       1430       1440       1450
SQSVQAPTSG SIVSSIGTLP SVPVSTTSAS TVGSAAAPGA KPPPVLSQQA 
      1460       1470       1480       1490       1500
AGSTTGIATL TSVSTTTPFP SIASQPAFQL SSSTSAPTLA ETVVISAHSL 
      1510       1520       1530       1540       1550
DKTSHSSATG LALSLSASSS SPGAGVSSSI SQPSGVHPLV IQSAVASTPV 
      1560       1570       1580       1590       1600
LPQAAGPTST PLLPQVPSIP PLVQPVASVP AVQQTLIHSQ PQPALLPNQP 
      1610       1620       1630       1640       1650
HTHCPEIDAD TQPKAPGIDD IKTLEEKLRS LFSEHSSSGA QHASVSLETS 
      1660       1670       1680       1690       1700
LVVETTVTPG IPTTAVAPSK LMTSTTSTCL PPTSLPLGTT GLSVIPVVTP 
      1710       1720       1730       1740       1750
GQVSTPVSYV SAPVSSTPGV KPGTTPSKPS LTKAPVLPVG TELPAGTLPS 
      1760       1770       1780       1790       1800
DQLPPFPGPS LTQQPLEDLD AQLRRTLSPE TVAVTSAVGP VSVVAPTAVT 
      1810       1820       1830       1840       1850
EAAAQPQKDV SQVTEGPVLA TTSGTGVFKM GRFQVSVAMD DAQKEGQSKS 
      1860       1870       1880       1890       1900
EDAKSVHFES STSESSVLSS SSPESTLVKP EPNSVTIHGI SSDVPDSAHK 
      1910       1920       1930       1940       1950
TPLLAAKSET GQSTKVGRFQ VTTTANKVGR FSVSRTEDKI AEAKKEGPMA 
      1960       1970       1980       1990       2000
SPPFMDLEQA TLPAVIPKKE KPELSEPSHL NGPSSDLEAA FLSRDVDDGS 
      2010       2020       2030       2040       2050
GSPHSPHQLS SKSLPVQNLS QSLSNSFNSS YMSSDNESDI EDEDLKLELR 
      2060       2070       2080       2090       2100
RLREKHLKEI QDLQSRQKHE IESLYTKLGK VPPAVIIPPA APLSGRRRRP 
      2110       2120       2130       2140       2150
TKSKGSKSSR SSSLGNKSPQ LSGNLSGQSS ASVLHPQQTL HPPGHMPESG 
      2160       2170       2180       2190       2200
QNQLLQPLKP SPSSDNLYSA FTSDGAISVP SLSAPGQGCA KFNCASEQVT 
      2210       2220       2230       2240       2250
FKPGGRRTRF LRKMVKKVCP CNQLCRTSST NTVGGTVNSQ AAQAQPPAMT 
      2260       2270       2280       2290       2300
SSRKGTFTDD LHKLVDNWAR DAMNLSGRRG SKGHMNYEGP GMARKFSAPG 
      2310       2320       2330       2340       2350
QLCISMTSNL GGSAPISAAS ATSLGHFTKS MCPPQQYGFP APPFGTQWSG 
      2360       2370       2380       2390 
TGGPAPQPLG QFQPVGTASL QNFNISNLQK SISNPPGSNL RTT
Length:2,393
Mass (Da):252,298
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9505819D1C68FAA5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A3Q2ID61A0A3Q2ID61_HORSE
Non-specific serine/threonine prote...
WNK1
2,881Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7BY14F7BY14_HORSE
Non-specific serine/threonine prote...
WNK1
2,585Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7C2Q9F7C2Q9_HORSE
Non-specific serine/threonine prote...
WNK1
2,421Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
F7BX86F7BX86_HORSE
Non-specific serine/threonine prote...
WNK1
2,681Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HGQ1A0A3Q2HGQ1_HORSE
Non-specific serine/threonine prote...
WNK1
2,398Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HSN6A0A3Q2HSN6_HORSE
Non-specific serine/threonine prote...
WNK1
2,795Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2HYK6A0A3Q2HYK6_HORSE
Non-specific serine/threonine prote...
WNK1
2,349Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A3Q2IC89A0A3Q2IC89_HORSE
Non-specific serine/threonine prote...
WNK1
2,290Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSECAT00000025398; ENSECAP00000021126; ENSECAG00000023501

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PaxDbiF7C849

Genome annotation databases

EnsembliENSECAT00000025398; ENSECAP00000021126; ENSECAG00000023501

Organism-specific databases

VGNCiVGNC:52460, WNK1

Phylogenomic databases

GeneTreeiENSGT00940000155474
InParanoidiF7C849
TreeFamiTF315363

Gene expression databases

BgeeiENSECAG00000023501, Expressed in brainstem and 23 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR011009, Kinase-like_dom_sf
IPR024678, Kinase_OSR1/WNK_CCT
IPR000719, Prot_kinase_dom
IPR008271, Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF12202, OSR1_C, 1 hit
PF00069, Pkinase, 1 hit
SMARTiView protein in SMART
SM00220, S_TKc, 1 hit
SUPFAMiSSF56112, SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50011, PROTEIN_KINASE_DOM, 1 hit
PS00108, PROTEIN_KINASE_ST, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF7C849_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7C849
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: December 2, 2020
This is version 61 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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