UniProtKB - F7BY74 (F7BY74_HORSE)
Protein
Submitted name:
Cap binding complex dependent translation initiation factor
Gene
CTIF
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: InterPro
- translation activator activity Source: GO_Central
GO - Biological processi
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: Ensembl
- regulation of translational initiation Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: Cap binding complex dependent translation initiation factorImported |
Gene namesi | Name:CTIFImported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:58685, CTIF |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Other locations
- perinuclear region of cytoplasm Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSECAG00000020473, Expressed in prefrontal cortex and 21 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 378 – 579 | MIF4GInterPro annotationAdd BLAST | 202 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 20 | DisorderedSequence analysisAdd BLAST | 20 | |
Regioni | 133 – 155 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 179 – 340 | DisorderedSequence analysisAdd BLAST | 162 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 17 | PolarSequence analysisAdd BLAST | 17 | |
Compositional biasi | 254 – 279 | PolyampholyteSequence analysisAdd BLAST | 26 | |
Compositional biasi | 320 – 334 | PolyampholyteSequence analysisAdd BLAST | 15 |
Phylogenomic databases
GeneTreei | ENSGT00940000153432 |
HOGENOMi | CLU_031968_0_0_1 |
InParanoidi | F7BY74 |
TreeFami | TF350740 |
Family and domain databases
Gene3Di | 1.25.40.180, 1 hit |
InterProi | View protein in InterPro IPR016024, ARM-type_fold IPR016021, MIF4-like_sf IPR003890, MIF4G-like_typ-3 |
Pfami | View protein in Pfam PF02854, MIF4G, 1 hit |
SMARTi | View protein in SMART SM00543, MIF4G, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
F7BY74-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MENSSAASAS SEAGSSRSQE IEELERFIDS YVLEYQVQGL LADKTEGDGE
60 70 80 90 100
SEKTQSHISQ WTADCREQLD SSCSFSRGRA APQQNGSKDN SLDMLGTDIW
110 120 130 140 150
AANTFDSFSG ATWDLQPEKL DFTQFHRKLR HTPKQPLPHI DREGCGKGKL
160 170 180 190 200
EDGDGINLND IEKVLPAWQG YHPMPHEVEI AHTKKLFRRR RNDRRRQQRP
210 220 230 240 250
PGGNKPQQHG DHQPGSAKHN RDHQKSYQGG SVPHPSGRPT HHGYSQNRRW
260 270 280 290 300
HHSNMKHPPG DKGESGAHRN AKETVAMESP KLEDALGDTG HSGLEPPRSP
310 320 330 340 350
DSLAPAASER LPPQQPGGPE AEARRKDSII PERIGERPKI TLLQSSKDRL
360 370 380 390 400
RRRLKEKVPD EVAVETTSPQ QNKMDKLIEI LNSMRNNSSD VDAKLTTFME
410 420 430 440 450
EAQNSTNSEE MLGEIVRTIY QKAVSDRSFA FTAAKLCDKM ALFMVEGTKF
460 470 480 490 500
RSLLLNMLQK DFTVREELQQ QDVERWLGFI TFLCEVFGTM RSSTGEPFRV
510 520 530 540 550
LVCPIYTCLR ELLQSQDVKE DAVLCCSMEL QSTGRLLEEQ LPEMMTELLA
560 570 580 590 600
SARDKMLCPS ESMLTRSLLL EVIELHANSW NPLTPPITQY YNRTIQKLTA
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PU52 | A0A5F5PU52_HORSE | Cap binding complex dependent trans... | CTIF | 574 | Annotation score: | ||
A0A5F5PY07 | A0A5F5PY07_HORSE | Cap binding complex dependent trans... | CTIF | 546 | Annotation score: |
Sequence databases
RefSeqi | XP_005612945.1, XM_005612888.2 |
Genome annotation databases
Ensembli | ENSECAT00000021723; ENSECAP00000017910; ENSECAG00000020473 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_005612945.1, XM_005612888.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F7BY74 |
Genome annotation databases
Ensembli | ENSECAT00000021723; ENSECAP00000017910; ENSECAG00000020473 |
Organism-specific databases
VGNCi | VGNC:58685, CTIF |
Phylogenomic databases
GeneTreei | ENSGT00940000153432 |
HOGENOMi | CLU_031968_0_0_1 |
InParanoidi | F7BY74 |
TreeFami | TF350740 |
Gene expression databases
Bgeei | ENSECAG00000020473, Expressed in prefrontal cortex and 21 other tissues |
Family and domain databases
Gene3Di | 1.25.40.180, 1 hit |
InterProi | View protein in InterPro IPR016024, ARM-type_fold IPR016021, MIF4-like_sf IPR003890, MIF4G-like_typ-3 |
Pfami | View protein in Pfam PF02854, MIF4G, 1 hit |
SMARTi | View protein in SMART SM00543, MIF4G, 1 hit |
SUPFAMi | SSF48371, SSF48371, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7BY74_HORSE | |
Accessioni | F7BY74Primary (citable) accession number: F7BY74 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | August 12, 2020 | |
This is version 50 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |