UniProtKB - F7BX73 (F7BX73_HORSE)
Protein
Submitted name:
Serine and arginine rich splicing factor 10
Gene
SRSF10
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: GO_Central
GO - Biological processi
- cytosolic transport Source: Ensembl
- mRNA cis splicing, via spliceosome Source: GO_Central
- mRNA splice site selection Source: Ensembl
- negative regulation of mRNA splicing, via spliceosome Source: Ensembl
- regulation of alternative mRNA splicing, via spliceosome Source: GO_Central
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Serine and arginine rich splicing factor 10Imported |
Gene namesi | Name:SRSF10Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:58653, SRSF10 |
Subcellular locationi
Cytosol
- cytosol Source: GOC
Nucleus
- nuclear speck Source: GO_Central
- nucleus Source: GO_Central
Other locations
- cytoplasm Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSECAG00000023709, Expressed in trophectoderm and 22 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 88 | RRMInterPro annotationAdd BLAST | 79 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 116 – 262 | DisorderedSequence analysisAdd BLAST | 147 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 154 – 168 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 183 – 197 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 205 – 237 | PolyampholyteSequence analysisAdd BLAST | 33 | |
Compositional biasi | 248 – 262 | PolarSequence analysisAdd BLAST | 15 |
Phylogenomic databases
GeneTreei | ENSGT00940000154450 |
HOGENOMi | CLU_012062_10_2_1 |
InParanoidi | F7BX73 |
TreeFami | TF351864 |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR034476, SRSF10 |
PANTHERi | PTHR23147:SF87, PTHR23147:SF87, 1 hit |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
F7BX73-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRYLRPPNT SLFVRNVADD TRSEDLRREF GRYGPIVDVY VPLDFYTRRP
60 70 80 90 100
RGFAYVQFED VRDAEDALHN LDRKWICGRQ IEIQFAQGDR KTPNQMKAKE
110 120 130 140 150
GRNVYSSSRY DDYDRYRRSR SRSYERRRSR SRSFDYNYRR SYSPRNSRPT
160 170 180 190 200
GRPRRSRSHS DNDRFKHRNR SFSRSKSNSR SRSKSQPKKE MKAKSRSRSA
210 220 230 240 250
SHTKARGTSK TDSKTHYKSG SRYEKESRKK EPPRSKSQSR SQSRSRSKSR
260
SRSWTSPKSS GH
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PZ04 | A0A5F5PZ04_HORSE | Serine and arginine rich splicing f... | SRSF10 | 173 | Annotation score: | ||
A0A5F5PYE2 | A0A5F5PYE2_HORSE | Serine and arginine rich splicing f... | SRSF10 | 183 | Annotation score: | ||
A0A5F5Q0Q8 | A0A5F5Q0Q8_HORSE | Serine and arginine rich splicing f... | SRSF10 | 165 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000025470; ENSECAP00000021188; ENSECAG00000023709 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F7BX73 |
PRIDEi | F7BX73 |
Genome annotation databases
Ensembli | ENSECAT00000025470; ENSECAP00000021188; ENSECAG00000023709 |
Organism-specific databases
VGNCi | VGNC:58653, SRSF10 |
Phylogenomic databases
GeneTreei | ENSGT00940000154450 |
HOGENOMi | CLU_012062_10_2_1 |
InParanoidi | F7BX73 |
TreeFami | TF351864 |
Gene expression databases
Bgeei | ENSECAG00000023709, Expressed in trophectoderm and 22 other tissues |
Family and domain databases
Gene3Di | 3.30.70.330, 1 hit |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR034476, SRSF10 |
PANTHERi | PTHR23147:SF87, PTHR23147:SF87, 1 hit |
Pfami | View protein in Pfam PF00076, RRM_1, 1 hit |
SMARTi | View protein in SMART SM00360, RRM, 1 hit |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F7BX73_HORSE | |
Accessioni | F7BX73Primary (citable) accession number: F7BX73 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | April 10, 2019 | |
Last modified: | August 12, 2020 | |
This is version 52 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |