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Protein
Submitted name:

Cyclin-dependent kinase inhibitor 1A

Gene

cdkn1a

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-XTR-176408 Regulation of APC/C activators between G1/S and early anaphase
R-XTR-187577 SCF(Skp2)-mediated degradation of p27/p21
R-XTR-198323 AKT phosphorylates targets in the cytosol
R-XTR-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-XTR-2559586 DNA Damage/Telomere Stress Induced Senescence
R-XTR-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
R-XTR-69202 Cyclin E associated events during G1/S transition
R-XTR-69231 Cyclin D associated events in G1
R-XTR-69563 p53-Dependent G1 DNA Damage Response
R-XTR-69656 Cyclin A:Cdk2-associated events at S phase entry

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin-dependent kinase inhibitor 1AImported
Gene namesi
Name:cdkn1aImported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
Proteomesi
  • UP000008143 Componenti: Unassembled WGS sequence

Organism-specific databases

XenbaseiXB-GENE-487802 cdkn1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF7BLZ9

Expressioni

Gene expression databases

BgeeiENSXETG00000024887 Expressed in 11 organ(s), highest expression level in embryo

Interactioni

Protein-protein interaction databases

STRINGi8364.ENSXETP00000053500

Structurei

3D structure databases

ProteinModelPortaliF7BLZ9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4743 Eukaryota
ENOG410XXN5 LUCA
GeneTreeiENSGT00530000063588
InParanoidiF7BLZ9
OMAiFAWERVW
OrthoDBiEOG091G19PZ
TreeFamiTF101038

Family and domain databases

InterProiView protein in InterPro
IPR003175 CDI
IPR029841 CDKN1A_vertebrate
PANTHERiPTHR10265 PTHR10265, 1 hit
PTHR10265:SF16 PTHR10265:SF16, 1 hit
PfamiView protein in Pfam
PF02234 CDI, 1 hit
PIRSFiPIRSF017811 CDK_inhib_pln, 2 hits

Sequencei

Sequence statusi: Complete.

F7BLZ9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSAIAILKQ ASGNKEKACR MLFEAVDHEQ LKTEFHELMQ RSNEEAKAKW
60 70 80 90 100
NFDFVTETPL EGQYDWEKVE DKTLNCNSQE SEKENQCQDV AAEMCNINQS
110 120 130
HKASQNCESS DSGKRKQKLI TDFYPVKRRC SPKPSPRD
Length:138
Mass (Da):15,949
Last modified:July 27, 2011 - v1
Checksum:iBC927B86E7EEF86C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01049902 Genomic DNA No translation available.
AAMC01049903 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSXETT00000053500; ENSXETP00000053500; ENSXETG00000024887

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAMC01049902 Genomic DNA No translation available.
AAMC01049903 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliF7BLZ9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000053500

Proteomic databases

PaxDbiF7BLZ9

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSXETT00000053500; ENSXETP00000053500; ENSXETG00000024887

Organism-specific databases

XenbaseiXB-GENE-487802 cdkn1a

Phylogenomic databases

eggNOGiKOG4743 Eukaryota
ENOG410XXN5 LUCA
GeneTreeiENSGT00530000063588
InParanoidiF7BLZ9
OMAiFAWERVW
OrthoDBiEOG091G19PZ
TreeFamiTF101038

Enzyme and pathway databases

ReactomeiR-XTR-176408 Regulation of APC/C activators between G1/S and early anaphase
R-XTR-187577 SCF(Skp2)-mediated degradation of p27/p21
R-XTR-198323 AKT phosphorylates targets in the cytosol
R-XTR-2559582 Senescence-Associated Secretory Phenotype (SASP)
R-XTR-2559586 DNA Damage/Telomere Stress Induced Senescence
R-XTR-6804116 TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest
R-XTR-69202 Cyclin E associated events during G1/S transition
R-XTR-69231 Cyclin D associated events in G1
R-XTR-69563 p53-Dependent G1 DNA Damage Response
R-XTR-69656 Cyclin A:Cdk2-associated events at S phase entry

Gene expression databases

BgeeiENSXETG00000024887 Expressed in 11 organ(s), highest expression level in embryo

Family and domain databases

InterProiView protein in InterPro
IPR003175 CDI
IPR029841 CDKN1A_vertebrate
PANTHERiPTHR10265 PTHR10265, 1 hit
PTHR10265:SF16 PTHR10265:SF16, 1 hit
PfamiView protein in Pfam
PF02234 CDI, 1 hit
PIRSFiPIRSF017811 CDK_inhib_pln, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiF7BLZ9_XENTR
AccessioniPrimary (citable) accession number: F7BLZ9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 12, 2018
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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