UniProtKB - F7BJB9 (MORC3_MOUSE)

BLAST

>sp|F7BJB9|MORC3_MOUSE MORC family CW-type zinc finger protein 3 OS=Mus musculus OX=10090 GN=Morc3 PE=1 SV=1
MAAQPPTGIRLSALCPKFLHTNSTSHTWPFSAVAELIDNAYDPDVNAKQIWIDKTVISDH
ICLTFTDNGNGMTADKLHKMLSFGFSDKVTMNGHVPVGLYGNGFKSGSMRLGKDAMVFTK
NGETMSVGFLSQTYLEVIKAEHVVVPIVTFNKHRQMINLTESKASLAAILEHSLFSTEQK
LLAELNAIMGKKGTRIIIWNLRSYKNATEFDFEKDKYDIRIPEDLDETAGRKGYKKQERM
DQIAPESDYSLRAYCSILYLKPRMQIIIRGQKVKTQLVSKSLAYIERDVYRPKFLTRTVR
ITFGFNCRNKDHYGIMMYHKNRLIKAYEKVGCQLKANNMGVGVVGIIECNFLKPTHNKQD
FDYTNEYRLTILALGEKLNDYWNEMKVKKNAEYPVNLPVEDIQKRPDQTWVQCDACLKWR
KLPDGIDQLPEKWYCSNNPDPQFRNCEVPEEPEDEDLVHPTYEKTYKKTSKERFRIRQPE
ILPRILPQINPELLYQTSVSSQSFSPVKESVPRPHLSEVTSPFAARIINLNLASPASEPE
NSSMKRKLGVHSSILNAKTRRLSNPPVENSSYKNDDDEDVIILEENSTPKPAVDLEVKSD
IEVKSEQSHTEQSGIHVDLVSSPKPCVQASSTSTSTSRSDPGITVSTQTDAPGLTVKKEE
SMEEDMGVRNGTATLSCVGTEAKVQETSAESVDATSHQLQELRSELLVVTQERDDYKRQC
QMFTDQIQVLQQRLLEMNDKCVKKEKCHQSTETDAVFLLDSVNGQAESLDHLGSQYQQAL
QEIERLKRQCSALQQVKSECSQASCTESKSEVDEMAVQLDDVFRQLDKCTIERDQYKNEV
QLLEIEKSHIHSQCEELQTEVEQLKSTGQQAAADGSTASNAEEPVSYVDGESLKLRSLRV
NVGQLLAMIVPDLDLQQVNYDVDVVDEILGQVVEQMSEISST

Align
Format
Add to basket Added to basket
History
Entry version 50 (07 Nov 2018)
Sequence version 1 (03 Oct 2012)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

MORC family CW-type zinc finger protein 3

Gene

Morc3

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (By similarity). Sumoylated MORC3-NBs can also associate with PML-NBs (By similarity). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (By similarity).By similarity1 Publication

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	404 – 454	CW-typePROSITE-ProRule annotationAdd BLAST		51

GO - Molecular functionⁱ

RNA binding Source: UniProtKB-KW
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	RNA-binding
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: MORC family CW-type zinc finger protein 3By similarity Alternative name(s): Nuclear matrix protein 2By similarity Zinc finger CW-type coiled-coil domain protein 3By similarity
Gene namesⁱ	Name:Morc3Imported Synonyms:Nxp2Imported, Zcwcc3Imported
Organismⁱ	Mus musculus (Mouse)Imported
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 16

Organism-specific databases

MGIⁱ	MGI:2136841 Morc3

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Disruption phenotypeⁱ

Lethality occurs at birth or within a day thereafter, for unknown reasons. Embryos at 14.5 dpc are morphologically indistinguishable from wild type.1 Publication

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000435141	1 – 942	MORC family CW-type zinc finger protein 3Add BLAST		942

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Cross-linkⁱ	191	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	205	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	280	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linkⁱ	293	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	517	PhosphoserineBy similarity	1
Modified residueⁱ	543	PhosphoserineBy similarity	1
Cross-linkⁱ	558	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residueⁱ	563	PhosphoserineCombined sources	1
Cross-linkⁱ	604	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linkⁱ	604	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Cross-linkⁱ	657	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linkⁱ	657	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Cross-linkⁱ	658	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linkⁱ	658	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Cross-linkⁱ	743	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linkⁱ	743	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity
Modified residueⁱ	768	PhosphoserineBy similarity	1
Cross-linkⁱ	797	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternateBy similarity
Cross-linkⁱ	797	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternateBy similarity

Post-translational modificationⁱ

Sumoylation is involved in interaction with PML and localization to PML nuclear bodies.By similarity

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	F7BJB9
PaxDbⁱ	F7BJB9
PRIDEⁱ	F7BJB9

PTM databases

iPTMnetⁱ	F7BJB9
PhosphoSitePlusⁱ	F7BJB9

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000039456 Expressed in 280 organ(s), highest expression level in lymph node
ExpressionAtlasⁱ	F7BJB9 baseline and differential
Genevisibleⁱ	Q6A0C2 MM

Interactionⁱ

Subunit structureⁱ

Homodimer. The sumoylated form interacts with PML (via SUMO-interacting motif). Interacts with PT53.1 Publication

Protein-protein interaction databases

IntActⁱ	F7BJB9, 3 interactors
STRINGⁱ	10090.ENSMUSP00000040152

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	18 – 21	Combined sources	4
Turnⁱ	22 – 25	Combined sources	4
Helixⁱ	29 – 41	Combined sources	13
Turnⁱ	43 – 45	Combined sources	3
Beta strandⁱ	48 – 57	Combined sources	10
Beta strandⁱ	60 – 67	Combined sources	8
Helixⁱ	74 – 80	Combined sources	7
Beta strandⁱ	82 – 84	Combined sources	3
Helixⁱ	103 – 111	Combined sources	9
Beta strandⁱ	112 – 131	Combined sources	20
Helixⁱ	132 – 137	Combined sources	6
Beta strandⁱ	147 – 151	Combined sources	5
Beta strandⁱ	156 – 158	Combined sources	3
Helixⁱ	159 – 172	Combined sources	14
Helixⁱ	178 – 186	Combined sources	9
Beta strandⁱ	190 – 201	Combined sources	12
Beta strandⁱ	203 – 211	Combined sources	9
Helixⁱ	246 – 249	Combined sources	4
Helixⁱ	251 – 257	Combined sources	7
Beta strandⁱ	258 – 261	Combined sources	4
Beta strandⁱ	264 – 268	Combined sources	5
Turnⁱ	279 – 281	Combined sources	3
Beta strandⁱ	282 – 290	Combined sources	9
Beta strandⁱ	299 – 308	Combined sources	10
Beta strandⁱ	314 – 319	Combined sources	6
Beta strandⁱ	322 – 328	Combined sources	7
Beta strandⁱ	342 – 348	Combined sources	7
Beta strandⁱ	358 – 361	Combined sources	4
Helixⁱ	365 – 385	Combined sources	21
Beta strandⁱ	408 – 412	Combined sources	5
Turnⁱ	414 – 416	Combined sources	3
Beta strandⁱ	419 – 422	Combined sources	4
Beta strandⁱ	431 – 433	Combined sources	3
Helixⁱ	435 – 437	Combined sources	3
Helixⁱ	441 – 443	Combined sources	3

Show more details

3D structure databases

ProteinModelPortalⁱ	F7BJB9
SMRⁱ	F7BJB9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	326 – 353	Nuclear matrix bindingBy similarityAdd BLAST		28
Regionⁱ	503 – 594	RNA bindingBy similarityAdd BLAST		92

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	696 – 874	Sequence analysisAdd BLAST		179

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	404 – 454	CW-typePROSITE-ProRule annotationAdd BLAST		51

Keywords - Domainⁱ

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1845 Eukaryota ENOG411033B LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000062983
HOGENOMⁱ	HOG000246950
HOVERGENⁱ	HBG055625
InParanoidⁱ	F7BJB9
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G018P
TreeFamⁱ	TF329118

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00075 HATPase_c, 1 hit
Gene3Dⁱ	3.30.565.10, 1 hit
InterProⁱ	View protein in InterPro IPR003594 HATPase_C IPR036890 HATPase_C_sf IPR011124 Znf_CW
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07496 zf-CW, 1 hit
SUPFAMⁱ	SSF55874 SSF55874, 1 hit
PROSITEⁱ	View protein in PROSITE PS51050 ZF_CW, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show all Align All

F7BJB9-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MAAQPPTGIR LSALCPKFLH TNSTSHTWPF SAVAELIDNA YDPDVNAKQI 
        60         70         80         90        100
WIDKTVISDH ICLTFTDNGN GMTADKLHKM LSFGFSDKVT MNGHVPVGLY 
       110        120        130        140        150
GNGFKSGSMR LGKDAMVFTK NGETMSVGFL SQTYLEVIKA EHVVVPIVTF 
       160        170        180        190        200
NKHRQMINLT ESKASLAAIL EHSLFSTEQK LLAELNAIMG KKGTRIIIWN 
       210        220        230        240        250
LRSYKNATEF DFEKDKYDIR IPEDLDETAG RKGYKKQERM DQIAPESDYS 
       260        270        280        290        300
LRAYCSILYL KPRMQIIIRG QKVKTQLVSK SLAYIERDVY RPKFLTRTVR 
       310        320        330        340        350
ITFGFNCRNK DHYGIMMYHK NRLIKAYEKV GCQLKANNMG VGVVGIIECN 
       360        370        380        390        400
FLKPTHNKQD FDYTNEYRLT ILALGEKLND YWNEMKVKKN AEYPVNLPVE 
       410        420        430        440        450
DIQKRPDQTW VQCDACLKWR KLPDGIDQLP EKWYCSNNPD PQFRNCEVPE 
       460        470        480        490        500
EPEDEDLVHP TYEKTYKKTS KERFRIRQPE ILPRILPQIN PELLYQTSVS 
       510        520        530        540        550
SQSFSPVKES VPRPHLSEVT SPFAARIINL NLASPASEPE NSSMKRKLGV 
       560        570        580        590        600
HSSILNAKTR RLSNPPVENS SYKNDDDEDV IILEENSTPK PAVDLEVKSD 
       610        620        630        640        650
IEVKSEQSHT EQSGIHVDLV SSPKPCVQAS STSTSTSRSD PGITVSTQTD 
       660        670        680        690        700
APGLTVKKEE SMEEDMGVRN GTATLSCVGT EAKVQETSAE SVDATSHQLQ 
       710        720        730        740        750
ELRSELLVVT QERDDYKRQC QMFTDQIQVL QQRLLEMNDK CVKKEKCHQS 
       760        770        780        790        800
TETDAVFLLD SVNGQAESLD HLGSQYQQAL QEIERLKRQC SALQQVKSEC 
       810        820        830        840        850
SQASCTESKS EVDEMAVQLD DVFRQLDKCT IERDQYKNEV QLLEIEKSHI 
       860        870        880        890        900
HSQCEELQTE VEQLKSTGQQ AAADGSTASN AEEPVSYVDG ESLKLRSLRV 
       910        920        930        940 
NVGQLLAMIV PDLDLQQVNY DVDVVDEILG QVVEQMSEIS ST

Length:942

Mass (Da):106,522

Last modified:October 3, 2012 - v1

Checksum:ⁱ29EFFF22B7B24C94

Computationally mapped potential isoform sequencesⁱ

There are 3 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

A0A0J9YU83	A0A0J9YU83_MOUSE	MORC family CW-type zinc finger pro... MORC family CW-type zinc finger protein 3	Morc3	397	Annotation score:
A0A0J9YUV3	A0A0J9YUV3_MOUSE	MORC family CW-type zinc finger pro... MORC family CW-type zinc finger protein 3	Morc3	92	Annotation score:
A0A338P7B1	A0A338P7B1_MOUSE	MORC family CW-type zinc finger pro... MORC family CW-type zinc finger protein 3	Morc3	58	Annotation score:

Sequence cautionⁱ

The sequence BAD32174 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	134	Y → H in AAH98072 (PubMed:15489334).Curated		1
Sequence conflictⁱ	679	G → S in AAI45706 (PubMed:15489334).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK172896 mRNA Translation: BAD32174.1 Different initiation. AC168220 Genomic DNA No translation available. BC098072 mRNA Translation: AAH98072.1 BC145705 mRNA Translation: AAI45706.1 BC026506 mRNA Translation: AAH26506.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS79490.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001038994.2, NM_001045529.3
UniGeneⁱ	Mm.287329

Genome annotation databases

Ensemblⁱ	ENSMUST00000044068; ENSMUSP00000040152; ENSMUSG00000039456 ENSMUST00000202261; ENSMUSP00000144369; ENSMUSG00000039456
GeneIDⁱ	338467
KEGGⁱ	mmu:338467
UCSC genome browser More...UCSCⁱ	uc008aaa.2 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
F7BJB9	MORC family CW-type zinc finger 3		RAT		942	UniRef90_F7BJB9
MORC family CW-type zinc finger protein 3 (Fragment)		MOUSE		397
UPI000A30E34F		MUSPA		942
UPI000A318BE6		MUSCR		943
MORC family CW-type zinc finger 3		RAT		679
+4

Protein	Similar proteins		Species	Score	Length	Source
F7BJB9	MORC family CW-type zinc finger protein 3	)	HUMAN		939	UniRef50_Q14149
MORC3 isoform 10 (Fragment)		PANTR		191
MORC family CW-type zinc finger 3		AILME		990
MORC family CW-type zinc finger protein 3		URSMA		962
Uncharacterized protein		MACMU		941
+356

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK172896 mRNA Translation: BAD32174.1 Different initiation. AC168220 Genomic DNA No translation available. BC098072 mRNA Translation: AAH98072.1 BC145705 mRNA Translation: AAI45706.1 BC026506 mRNA Translation: AAH26506.1
CCDSⁱ	CCDS79490.1
RefSeqⁱ	NP_001038994.2, NM_001045529.3
UniGeneⁱ	Mm.287329

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	5IX1	X-ray	2.60	A/B	7-456	[»]
	5IX2	X-ray	2.90	A/B	7-456	[»]
ProteinModelPortalⁱ	F7BJB9
SMRⁱ	F7BJB9
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	F7BJB9, 3 interactors
STRINGⁱ	10090.ENSMUSP00000040152

PTM databases

iPTMnetⁱ	F7BJB9
PhosphoSitePlusⁱ	F7BJB9

Proteomic databases

MaxQBⁱ	F7BJB9
PaxDbⁱ	F7BJB9
PRIDEⁱ	F7BJB9

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000044068; ENSMUSP00000040152; ENSMUSG00000039456 ENSMUST00000202261; ENSMUSP00000144369; ENSMUSG00000039456
GeneIDⁱ	338467
KEGGⁱ	mmu:338467
UCSCⁱ	uc008aaa.2 mouse

Organism-specific databases

CTDⁱ	23515
MGIⁱ	MGI:2136841 Morc3

Phylogenomic databases

eggNOGⁱ	KOG1845 Eukaryota ENOG411033B LUCA
GeneTreeⁱ	ENSGT00530000062983
HOGENOMⁱ	HOG000246950
HOVERGENⁱ	HBG055625
InParanoidⁱ	F7BJB9
OrthoDBⁱ	EOG091G018P
TreeFamⁱ	TF329118

Miscellaneous databases

ChiTaRSⁱ	Morc3 mouse
Protein Ontology More...PROⁱ	PR:F7BJB9
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000039456 Expressed in 280 organ(s), highest expression level in lymph node
ExpressionAtlasⁱ	F7BJB9 baseline and differential
Genevisibleⁱ	Q6A0C2 MM

Family and domain databases

CDDⁱ	cd00075 HATPase_c, 1 hit
Gene3Dⁱ	3.30.565.10, 1 hit
InterProⁱ	View protein in InterPro IPR003594 HATPase_C IPR036890 HATPase_C_sf IPR011124 Znf_CW
Pfamⁱ	View protein in Pfam PF07496 zf-CW, 1 hit
SUPFAMⁱ	SSF55874 SSF55874, 1 hit
PROSITEⁱ	View protein in PROSITE PS51050 ZF_CW, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	MORC3_MOUSE
Accessionⁱ	F7BJB9Primary (citable) accession number: F7BJB9 Secondary accession number(s): A6H605 , Q4QQR6, Q6A0C2, Q8R0R0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 20, 2016
	Last sequence update:	October 3, 2012
	Last modified:	November 7, 2018
	This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - F7BJB9 (MORC3_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

MORC family CW-type zinc finger protein 3

Morc3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Coiled coil

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Sequence cautionⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ