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Protein

Actin-related protein 2/3 complex subunit 4

Gene

ARPC4

Organism
Callithrix jacchus (White-tufted-ear marmoset)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActin-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Actin-related protein 2/3 complex subunit 4UniRule annotation
Gene namesi
Name:ARPC4Imported
OrganismiCallithrix jacchus (White-tufted-ear marmoset)Imported
Taxonomic identifieri9483 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeCallitrichinaeCallithrixCallithrix
Proteomesi
  • UP000008225 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, CytoskeletonUniRule annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9483.ENSCJAP00000051909

Family & Domainsi

Sequence similaritiesi

Belongs to the ARPC4 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1876 Eukaryota
ENOG4111G2F LUCA
GeneTreeiENSGT00390000016233
InParanoidiF7BGP2
OMAiFASKLWT
OrthoDBiEOG091G0OI8
TreeFamiTF105621

Family and domain databases

Gene3Di3.30.1460.20, 1 hit
InterProiView protein in InterPro
IPR034666 ARPC2/4
IPR008384 ARPC4
PANTHERiPTHR22629 PTHR22629, 1 hit
PfamiView protein in Pfam
PF05856 ARPC4, 1 hit
PIRSFiPIRSF039100 ARPC4, 1 hit
SUPFAMiSSF69645 SSF69645, 1 hit

Sequencei

Sequence statusi: Complete.

F7BGP2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVREPGPELG TPSCSASGLW TATLRPYLSA VRATLQAALC LENFSSQVVE
60 70 80 90 100
RHNKPEVEVR SSKELLLQPV TISRNEKEKV LIEGSINSVR VSIAVKQADE
110 120 130 140 150
IEKILCHKFM RFMMMRAENF FILRRKPVEG YDISFLITNF HTEQMYKHKL
160 170 180
VDFVIHFMEE IDKEISEMKL SVNARARIVA EEFLKNF
Length:187
Mass (Da):21,592
Last modified:July 27, 2011 - v1
Checksum:i61601E3A2725F7BF
GO

Genome annotation databases

EnsembliENSCJAT00000059436; ENSCJAP00000051909; ENSCJAG00000016175

Similar proteinsi

Entry informationi

Entry nameiF7BGP2_CALJA
AccessioniPrimary (citable) accession number: F7BGP2
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 20, 2018
This is version 31 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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