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Protein
Submitted name:

Fibronectin leucine rich transmembrane protein 2

Gene

FLRT2

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Fibronectin leucine rich transmembrane protein 2Imported
Submitted name:
Leucine-rich repeat transmembrane protein FLRT2Imported
Gene namesi
Name:FLRT2Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei541 – 564HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 35Sequence analysisAdd BLAST35
ChainiPRO_501409067836 – 660Sequence analysisAdd BLAST625

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMMUG00000020664

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000027192

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini419 – 517Fibronectin type-IIIInterPro annotationAdd BLAST99

Keywords - Domaini

Leucine-rich repeatSAAS annotation, RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IHC8 Eukaryota
ENOG4111ID7 LUCA
GeneTreeiENSGT00920000148996
KOiK16362
OMAiFPAELHN
OrthoDBiEOG091G05YU
TreeFamiTF315838

Family and domain databases

Gene3Di2.60.40.10, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR000483 Cys-rich_flank_reg_C
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR013783 Ig-like_fold
IPR001611 Leu-rich_rpt
IPR003591 Leu-rich_rpt_typical-subtyp
IPR032675 LRR_dom_sf
IPR000372 LRRNT
PfamiView protein in Pfam
PF00041 fn3, 1 hit
PF13855 LRR_8, 3 hits
PF01463 LRRCT, 1 hit
SMARTiView protein in SMART
SM00369 LRR_TYP, 7 hits
SM00082 LRRCT, 1 hit
SM00013 LRRNT, 1 hit
SUPFAMiSSF49265 SSF49265, 1 hit
PROSITEiView protein in PROSITE
PS50853 FN3, 1 hit

Sequencei

Sequence statusi: Complete.

F7BEN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLQTTKWPS HGAFFLKSWL IISLGLYSQV SKLLACPSVC RCDRNFVYCN
60 70 80 90 100
ERSLTSVPLG IPEGVTVLYL HNNQINNAGF PAELHNVQSV HTVYLYGNQL
110 120 130 140 150
DEFPMNLPKN VRVLHLQENN IQTISRAALA QLLKLEELHL DDNSISTVGV
160 170 180 190 200
EDGAFREAIS LKLLFLSKNH LSSVPVGLPV DLQELRVDEN RIAVISDMAF
210 220 230 240 250
QNLTSLERLI VDGNLLTNKG IADGTFSHLT KLKEFSIVRN SLSHPPPDLP
260 270 280 290 300
GTHLIRLYLQ DNQINHIPLT AFSNLRKLER LDISNNQLRM LTQGVFDNLS
310 320 330 340 350
NLKQLTARNN PWFCDCSIKW VTEWLKYIPS SLNVRGFMCQ GPEQVRGMAV
360 370 380 390 400
RELNMNLLSC PTTTPGLPLF TPAPSTASPT TQPPTLSIPN PSRSHTPPTP
410 420 430 440 450
TTSKLPTIPD WDGRERVTPP ISERIQLSIH FVNDTSIQVS WLSLFTVMAY
460 470 480 490 500
KLTWVKMGHS LVGGIVQERI VSGEKQHLSL VNLEPRSTYR ICLVPLDAFN
510 520 530 540 550
YRAVEDTICS EATTHASYLN NGSNTASSHE QTTSHSMGSP FLLAGLIGGA
560 570 580 590 600
VIFVLMVLLS VFCWHMHKKG RYTSQKWKYN RGRRKDDYCE AGTKKDNSIL
610 620 630 640 650
EMTETSFQIV SLNNDQLLKG DFRLQPIYTP NGGINYTDCH IPNNMRYCNS
660
SVPDLEHCHT
Length:660
Mass (Da):74,041
Last modified:July 27, 2011 - v1
Checksum:iF98F366A43B78814
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03040232 Genomic DNA No translation available.
JU319924 mRNA Translation: AFE63680.1
JV043836 mRNA Translation: AFI33907.1
RefSeqiNP_001253402.1, NM_001266473.1
XP_014999750.1, XM_015144264.1
XP_014999751.1, XM_015144265.1
UniGeneiMmu.943

Genome annotation databases

EnsembliENSMMUT00000029064; ENSMMUP00000027192; ENSMMUG00000020664
GeneIDi709329
KEGGimcc:709329

Similar proteinsi

Entry informationi

Entry nameiF7BEN4_MACMU
AccessioniPrimary (citable) accession number: F7BEN4
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 20, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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