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Protein
Submitted name:

Membrane metalloendopeptidase

Gene

MME

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Protein family/group databases

MEROPSiM13.001

Names & Taxonomyi

Protein namesi
Submitted name:
Membrane metalloendopeptidaseImported
Gene namesi
Name:MMEImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 16

Organism-specific databases

VGNCiVGNC:20220 MME

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei29 – 52HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiF7B8E7

Expressioni

Gene expression databases

BgeeiENSECAG00000009138

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000007949

Structurei

3D structure databases

ProteinModelPortaliF7B8E7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini79 – 483Peptidase_M13_NInterPro annotationAdd BLAST405
Domaini543 – 749Peptidase_M13InterPro annotationAdd BLAST207

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili269 – 289Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3624 Eukaryota
COG3590 LUCA
GeneTreeiENSGT00760000119162
InParanoidiF7B8E7
KOiK01389
OMAiTATWRRC
OrthoDBiEOG091G025Y
TreeFamiTF315192

Family and domain databases

CDDicd08662 M13, 1 hit
Gene3Di3.40.390.10, 3 hits
InterProiView protein in InterPro
IPR024079 MetalloPept_cat_dom_sf
IPR029727 MME/CD10/NEP
IPR000718 Peptidase_M13
IPR018497 Peptidase_M13_C
IPR008753 Peptidase_M13_N
PANTHERiPTHR11733 PTHR11733, 1 hit
PTHR11733:SF114 PTHR11733:SF114, 1 hit
PfamiView protein in Pfam
PF01431 Peptidase_M13, 1 hit
PF05649 Peptidase_M13_N, 1 hit
PRINTSiPR00786 NEPRILYSIN

Sequencei

Sequence statusi: Complete.

F7B8E7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRSESQMDI TDINTPKPKK QQRWTPLEVS LSVLVVLLTV IAVTTIALYA
60 70 80 90 100
TYDDGICKSS DCIKSAARLI QNMDATAEPC ANFFKYACGG WLKRNIIPET
110 120 130 140 150
SSRYGNFDIL RDELEVVLKD VLQETKTEDI AAVQKAKTLY RSCVNESVID
160 170 180 190 200
SRGGEPLLRL LPDIYDWPVA TENWEQVYGT SWTAEKSIAQ LNSKYGKKVI
210 220 230 240 250
INFFVGTDDK NSMNHIIHID QPRLGLPSRD YYECTGIYKE ACTAYVDFMI
260 270 280 290 300
SVAKLIRQEK GLPIDENQLS SEMNKVMELE KEIANATAKP EDRNDPILLY
310 320 330 340 350
NKMTLAQIQS NFSLEINGKP FSWANFTNEI MSTVNINIPN EEDVVVYAPE
360 370 380 390 400
YLTKLKLILT KYSARDLQNL MSWRFIMDLV SSLSRTYKES RNAFRKALYG
410 420 430 440 450
TTSETATWRR CANYVNGNME NAVGRLYVEA AFAGESKHVV ENLIAQIREV
460 470 480 490 500
FIQTLDDLTW MDAETKKKAE EKALAIKERI GYPDEIISND SKLDNEYLEL
510 520 530 540 550
NYKEDEYFEN IIQNLKFSQN KQLKKLREKV DKDEWISGAA VVNAFYSSGR
560 570 580 590 600
NQIVFPAGIL QPPFFSAQQS NSLNYGGIGM VIGHEITHGF DDNGRNFNKD
610 620 630 640 650
GDLVDWWTQQ SANNFKEQSQ CMVYQYGNFS WDLAGGQHLN GINTLGENIA
660 670 680 690 700
DNGGIGQAYR AYQNYVKKNG EEKLLPGIDL NHKQLFFLNF AQVWCGTYRP
710 720 730 740 750
EYAINSIKTD VHSPGSFRII GTLQNSPEFS EAFHCPKNSY MNPEKKCRVW
Length:750
Mass (Da):85,407
Last modified:July 27, 2011 - v1
Checksum:iE03A3D0F9D600D2D
GO

Sequence databases

RefSeqiXP_005601073.1, XM_005601016.2
XP_014587415.1, XM_014731929.1

Genome annotation databases

EnsembliENSECAT00000010316; ENSECAP00000007949; ENSECAG00000009138
GeneIDi100053541
KEGGiecb:100053541

Similar proteinsi

Entry informationi

Entry nameiF7B8E7_HORSE
AccessioniPrimary (citable) accession number: F7B8E7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 40 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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