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Protein
Submitted name:

3-phosphoinositide dependent protein kinase 1

Gene

PDPK1

Organism
Macaca mulatta (Rhesus macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
3-phosphoinositide dependent protein kinase 1Imported
Gene namesi
Name:PDPK1Imported
OrganismiMacaca mulatta (Rhesus macaque)Imported
Taxonomic identifieri9544 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000006718 Componenti: Chromosome 20

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMMUG00000011459 Expressed in 14 organ(s), highest expression level in prefrontal cortex
ExpressionAtlasiF7B364 baseline

Interactioni

Protein-protein interaction databases

STRINGi9544.ENSMMUP00000015038

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini83 – 343Protein kinaseInterPro annotationAdd BLAST261

Phylogenomic databases

eggNOGiKOG0592 Eukaryota
ENOG410XRT8 LUCA
GeneTreeiENSGT00920000149082
InParanoidiF7B364
OrthoDBiEOG091G06CX
TreeFamiTF105423

Family and domain databases

CDDicd01262 PH_PDK1, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR033931 PDK1-typ_PH
IPR039046 PDPK1
IPR011993 PH-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR24356:SF163 PTHR24356:SF163, 1 hit
PfamiView protein in Pfam
PF14593 PH_3, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.iShow all

F7B364-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGRTRERRPY DAVPIQSSVV LCSCPSPSMV RTQTESSTAP GIPGGSRQGP
60 70 80 90 100
TMDGTAAEPR PGAGSLQHAQ PPPQPRKKRP EDFKFGKILG EGSFSTVVLA
110 120 130 140 150
RELATSREYA IKILEKRHII KENKVPYVTR ERDVMSRLDH PFFVKLYFTF
160 170 180 190 200
QDDEKLYFGL SYAKNGELLK YIRKIGSFDE TCTRFYTAEI VSALEYLHGK
210 220 230 240 250
GIIHRDLKPE NILLNEDMHI QITDFGTAKV LSPESKQARA NSFVGTAQYV
260 270 280 290 300
SPELLTEKSA CKSSDLWALG CIIYQLVAGL PPFRAGNEYL IFQKIIKLEY
310 320 330 340 350
DFPEKFFPKA RDLVEKLLVL DATKRLGCEE MEGYGPLKAH PFFESVTWEN
360 370 380 390 400
LHQQTPPKLT AYLPAMSEDD EDCYGNYDNL LSQFGCMQLS LSSSSHSLSA
410 420 430 440 450
SDVGLPQRSG SNIEQYIHDL DSNSFELDLQ FSEDEKRLLL EKQAGGNPWH
460 470 480 490 500
QFVENNLILK MGPVDKRKGL FARRRQLLLT EGPHLYYVDP VNKVLKGEIP
510 520 530 540 550
WSQELRPEAK NFKTFFVHTP NRTYYLMDPS GNAHKWCRKI QEVWRQRYQS

HPDAAVQ
Length:557
Mass (Da):63,445
Last modified:November 30, 2016 - v2
Checksum:i62306DF3DAFAE005
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1D5QMJ4A0A1D5QMJ4_MACMU
3-phosphoinositide dependent protei...
PDPK1
597Annotation score:
F7B371F7B371_MACMU
3-phosphoinositide dependent protei...
PDPK1
454Annotation score:
H9ESX9H9ESX9_MACMU
3-phosphoinositide dependent protei...
PDPK1
556Annotation score:
A0A1D5QJZ0A0A1D5QJZ0_MACMU
3-phosphoinositide dependent protei...
PDPK1
529Annotation score:
A0A1D5RGP4A0A1D5RGP4_MACMU
3-phosphoinositide dependent protei...
PDPK1
429Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
JSUE03025467 Genomic DNA No translation available.
JSUE03025468 Genomic DNA No translation available.
JSUE03025469 Genomic DNA No translation available.
JSUE03025470 Genomic DNA No translation available.
JSUE03025471 Genomic DNA No translation available.
JSUE03025472 Genomic DNA No translation available.

Genome annotation databases

EnsembliENSMMUT00000016045; ENSMMUP00000015038; ENSMMUG00000011459

Similar proteinsi

Entry informationi

Entry nameiF7B364_MACMU
AccessioniPrimary (citable) accession number: F7B364
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: November 30, 2016
Last modified: September 12, 2018
This is version 40 of the entry and version 2 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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