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Entry version 41 (16 Jan 2019)
Sequence version 1 (03 Oct 2012)
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Protein

Otogelin-like protein

Gene

Otogl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Otogelin-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Otogl
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:3647600 Otogl

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 22Sequence analysisAdd BLAST22
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000042110623 – 2325Otogelin-like proteinAdd BLAST2303

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi136 ↔ 144By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi425N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi817N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi867N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1280N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1576N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2170N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2233 ↔ 2289By similarity
Disulfide bondi2254 ↔ 2303By similarity
Disulfide bondi2265 ↔ 2320By similarity
Disulfide bondi2269 ↔ 2322By similarity
Glycosylationi2296N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F7A4A7

PRoteomics IDEntifications database

More...
PRIDEi
F7A4A7

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
F7A4A7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

At 17.5 dpc, primarily detected in the spiral prominence and the Claudius cells and weakly in hair cells (at protein level). Also detected in the lumen surface of interdental cells in the proximity of Reissner's membrane and at the base of nascent tectorial membrane (at protein level). Similar expression pattern in P0 cochlea, with additional detection in some supporting cells (at protein level). At the same stage, in saccule, weakly expressed in hair cells and more prominently in the saccular roof (at protein level). By P6, expression becomes more restricted. Mainly detected in the outer hair cells, Deiter's cells and Claudius cells (at protein level). In the tectorial membrane, localized to the base. In the saccule, detected at high levels in the saccule roof with little change in the hair cells (at protein level).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000091455 Expressed in 12 organ(s), highest expression level in spiral organ of cochlea

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000129467

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
F7A4A7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini113 – 326VWFD 1PROSITE-ProRule annotationAdd BLAST214
Domaini473 – 683VWFD 2PROSITE-ProRule annotationAdd BLAST211
Domaini736 – 791TIL 1Add BLAST56
Domaini938 – 1141VWFD 3PROSITE-ProRule annotationAdd BLAST204
Domaini1366 – 1418TIL 2Add BLAST53
Domaini1507 – 1727VWFD 4PROSITE-ProRule annotationAdd BLAST221
Domaini2233 – 2325CTCKPROSITE-ProRule annotationAdd BLAST93

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1901 – 2088Cys-richAdd BLAST188

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the otogelin family.Curated

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1216 Eukaryota
ENOG410XNSK LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000160698

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F7A4A7

Identification of Orthologs from Complete Genome Data

More...
OMAi
DCSHCIE

Database of Orthologous Groups

More...
OrthoDBi
12226at2759

TreeFam database of animal gene trees

More...
TreeFami
TF330609

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007934 AbfB_ABD
IPR036195 AbfB_ABD_sf
IPR006207 Cys_knot_C
IPR030110 Otogl
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D

The PANTHER Classification System

More...
PANTHERi
PTHR11339:SF225 PTHR11339:SF225, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05270 AbfB, 1 hit
PF08742 C8, 4 hits
PF01826 TIL, 2 hits
PF00094 VWD, 4 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00832 C8, 4 hits
SM00041 CT, 1 hit
SM00215 VWC_out, 2 hits
SM00216 VWD, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF110221 SSF110221, 1 hit
SSF57567 SSF57567, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01225 CTCK_2, 1 hit
PS51233 VWFD, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: F7A4A7-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MVPWRALSLP ILLVSLRGYV CASSVLSETS ESEFYENEQR RALLAVQFEA
60 70 80 90 100
TSPRYFFHEA INWGESKIKG SCPHECLNGA FCSKTGTCDC QIFQALGTRC
110 120 130 140 150
QIVPNMGSGR DGICKTWGQY HFETFDGIYY YFPGSCSYIF AKDCGNLEPQ
160 170 180 190 200
YTVWVHNSPK CLGSVYSCYR SISLFFSNQE EIRIYGHEIR KNGISLSLPQ
210 220 230 240 250
TLGQVHLEKV ADYILVKTTF GFSLAWDGIS GIYLKLSEEH RGKSCGLCAN
260 270 280 290 300
YNGIQSDDFV ILQEDYTEDI AMFANSWLVL TPDDTKCVPT PSDFPNPCSS
310 320 330 340 350
GMPAFEAIFF KCQILLQFPF LSCHEYIDPY LYIASCVNDL CKTDDDETYC
360 370 380 390 400
RAATEYARAC SHAGFPIQDW RDDFPACTDK CDDSFVHRDC ISCCPPSCTF
410 420 430 440 450
EKQCLGSNLH CLDGCYCADG LIMDNGTCIS LESCPCSFHG LAYSVGSKIE
460 470 480 490 500
QECTECVCVG GVWNCTEHDC PVQCSVVGDS HFTTFDGRHY SFIGLCQYIL
510 520 530 540 550
VKGTGKDRFT ITLQKAHCEQ NLGLVCLQSI TLILEDDFNK QVTLSRGGQI
560 570 580 590 600
VTSPNQGFTL NGIVEIQTLS SLFILLRTTF GLKILFAIDG ERIYIQLSSA
610 620 630 640 650
WKRRTLGLCG TFNGNIRDDF LSPSGMIEGT PQLHAHAWRV SSTCFAPVHV
660 670 680 690 700
PMVDPCNINQ QNIGYAAHCD VIHQELFAPC HVYVSPGLYY QLCRHDACKC
710 720 730 740 750
GSPCLCNALA HYAYLCGQRG VPIDFRAHIS FCAVVCQKGM LYHHCSSLCL
760 770 780 790 800
RSCTSLSSPE QCKDDCAEGC NCPEGKFYEE TLNFCVPIYH CRCHYRGSIY
810 820 830 840 850
QPGELIPTPS GLCQCSNGTV KCDELATPST VHACPEGKEY FDCRFPDPAL
860 870 880 890 900
PAGGINCETT CANLAMNFTC APSSPCISGC VCAAGMAEHK GKCYVPESCP
910 920 930 940 950
CIWKDWEYSS GEVISTPCYT CVCRRGMFNC TYYPCPAVCT VYGDRHYHSF
960 970 980 990 1000
DGLEYDYISD CQVFLIKSTD DSDISVISQN KKCFDNDIVC SKSVLISIGD
1010 1020 1030 1040 1050
TEIYLNDAPY KQKRSGFFLE SRPEYQLWKA GFYIVIYFPE EDITILWDEK
1060 1070 1080 1090 1100
TTIHIKVGPQ WKNKLAGLCG NFDKCTSNDM TTSNNIEVRN AQVFGDSWAL
1110 1120 1130 1140 1150
GQCEDLMEAL KPCEAHQNKF PYAKRECSIL YSDVFAPCRN VIDVTSFAKN
1160 1170 1180 1190 1200
CHEDTCNCNL GGDCECLCTS VAAYAYKCCQ EGVPVHWRSP TVCALDCEYY
1210 1220 1230 1240 1250
NQGLGEGPYM LASYGQSGLV LGANMTSRSV FSLPRSNNRG NLFFIFMITP
1260 1270 1280 1290 1300
GLFKEKTSSL ALVSLESAER PNYFLYVHDN DTLSLKLWRA NSEFHQRATF
1310 1320 1330 1340 1350
FHHQGLWIPG YSAFELYSKK GYFIVFMGSS VKASKYDDSE EFKQSSSFSI
1360 1370 1380 1390 1400
EEIQAVVPYR RMCEWRYEPC ATPCFKTCSD PEALACTFLP PVEGCLPYCP
1410 1420 1430 1440 1450
KNMILDETTL KCVHPEDCIP LFPTEPALPP DITPSDMTPT PGLECEPQQF
1460 1470 1480 1490 1500
DPVYNCSQYI CLNMEWTFYN WSLNCPKDLE MPDCGFRGWP VQVNTDICCP
1510 1520 1530 1540 1550
EWECPCRCSM LSELSIITFD GNSAALSSMA SYILVRVPGE IVVVHIDKCS
1560 1570 1580 1590 1600
MNQNGHALKK PASFGRISGL CFKKLNVTTS IHKILINRVV RKVDVDSIVV
1610 1620 1630 1640 1650
PLPFSSHELF IEDSGTMYVI TTPAGLIIKW AHLTGIIDIH FGPQFNLSSY
1660 1670 1680 1690 1700
TEGLCGICND NPDDDLRMQN GTIITNMEDI ELFIGSWEIE KSFEVTMRRP
1710 1720 1730 1740 1750
VRNCTEYDCS HCIELLNREG FIPCHDKVSP RDFCEKMWIN YTYFWSYECD
1760 1770 1780 1790 1800
AISAYVALCN KFDICIQWRT PDYCPLSCPE GKEYQPCVRP CEARTCLNKW
1810 1820 1830 1840 1850
FYGHSSCLNL REDCVCKNGT ILHRPDKTLC IPEQECVCTD REEHPRSAGE
1860 1870 1880 1890 1900
IWNGGIDECT LYKCLEDGNI IPIEPVCEEE PSPICERTAE VVIGIVDKLT
1910 1920 1930 1940 1950
CCSKKVCGCD MSLCDRTIPP CTNSQKLIVG YSALSCCPQY ECECDTVRCP
1960 1970 1980 1990 2000
DISTPVCRDD QFVLQVRQGE PCCFYPSCVC KTCTEPTPQC TDGEFLTVNI
2010 2020 2030 2040 2050
NTTHLCCPQY YCVCEPDLCP PPSLECAKDM NLVKENVSGQ CCPNWRCECN
2060 2070 2080 2090 2100
CETLVMPTCD VGEFAAIDQN FQTDCGCVQY LCEKDDVCVF QEVSVLNPGQ
2110 2120 2130 2140 2150
SLIKYLEEEF CYIIECLDEK DNYTDFHTLN VTMVNCSKDC DAHQIYIPSS
2160 2170 2180 2190 2200
SDYDCCGTCK NISCKFIMEN GTSVIYEEGS TWHYNCSTYE CVNTEEGATI
2210 2220 2230 2240 2250
LNYSMVCPPF NETECKLNEG IVKLYNEGCC KICKREERIC QKVIIKSIIK
2260 2270 2280 2290 2300
KQDCVSQSSI SVASCDGKCP SATIYNINVE SHLRFCKCCR ENGVRNVTVP
2310 2320
LHCSGNGTEV MYTLQEPIDC TCQWN
Length:2,325
Mass (Da):260,929
Last modified:October 3, 2012 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9E446F218E3F091A
GO
Isoform 2 (identifier: F7A4A7-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     2258-2325: SSISVASCDG...EPIDCTCQWN → RLVWHLVMGNARQLPYITSMLKVT

Show »
Length:2,281
Mass (Da):256,272
Checksum:iE25FF2C7F2F50276
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0451772258 – 2325SSISV…TCQWN → RLVWHLVMGNARQLPYITSM LKVT in isoform 2. 1 PublicationAdd BLAST68

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GU140005 mRNA Translation: ADC39942.1
AC113439 Genomic DNA No translation available.
AC123948 Genomic DNA No translation available.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS56747.1 [F7A4A7-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001171038.1, NM_001177567.1 [F7A4A7-1]

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.336090

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000165341; ENSMUSP00000129467; ENSMUSG00000091455 [F7A4A7-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
628870

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:628870

UCSC genome browser

More...
UCSCi
uc011xnc.1 mouse [F7A4A7-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GU140005 mRNA Translation: ADC39942.1
AC113439 Genomic DNA No translation available.
AC123948 Genomic DNA No translation available.
CCDSiCCDS56747.1 [F7A4A7-1]
RefSeqiNP_001171038.1, NM_001177567.1 [F7A4A7-1]
UniGeneiMm.336090

3D structure databases

SMRiF7A4A7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129467

PTM databases

PhosphoSitePlusiF7A4A7

Proteomic databases

PaxDbiF7A4A7
PRIDEiF7A4A7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000165341; ENSMUSP00000129467; ENSMUSG00000091455 [F7A4A7-1]
GeneIDi628870
KEGGimmu:628870
UCSCiuc011xnc.1 mouse [F7A4A7-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
283310
MGIiMGI:3647600 Otogl

Phylogenomic databases

eggNOGiKOG1216 Eukaryota
ENOG410XNSK LUCA
GeneTreeiENSGT00940000160698
InParanoidiF7A4A7
OMAiDCSHCIE
OrthoDBi12226at2759
TreeFamiTF330609

Miscellaneous databases

Protein Ontology

More...
PROi
PR:F7A4A7

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000091455 Expressed in 12 organ(s), highest expression level in spiral organ of cochlea

Family and domain databases

InterProiView protein in InterPro
IPR007934 AbfB_ABD
IPR036195 AbfB_ABD_sf
IPR006207 Cys_knot_C
IPR030110 Otogl
IPR036084 Ser_inhib-like_sf
IPR002919 TIL_dom
IPR014853 Unchr_dom_Cys-rich
IPR001007 VWF_dom
IPR001846 VWF_type-D
PANTHERiPTHR11339:SF225 PTHR11339:SF225, 2 hits
PfamiView protein in Pfam
PF05270 AbfB, 1 hit
PF08742 C8, 4 hits
PF01826 TIL, 2 hits
PF00094 VWD, 4 hits
SMARTiView protein in SMART
SM00832 C8, 4 hits
SM00041 CT, 1 hit
SM00215 VWC_out, 2 hits
SM00216 VWD, 4 hits
SUPFAMiSSF110221 SSF110221, 1 hit
SSF57567 SSF57567, 5 hits
PROSITEiView protein in PROSITE
PS01225 CTCK_2, 1 hit
PS51233 VWFD, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOTOGL_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F7A4A7
Secondary accession number(s): D3JEN5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2013
Last sequence update: October 3, 2012
Last modified: January 16, 2019
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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