UniProtKB - F6Z4X1 (F6Z4X1_HORSE)
Protein
Submitted name:
Autophagy and beclin 1 regulator 1
Gene
AMBRA1
Organism
Equus caballus (Horse)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Autophagy and beclin 1 regulator 1Imported |
Gene namesi | Name:AMBRA1Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:15273, AMBRA1 |
Expressioni
Gene expression databases
Bgeei | ENSECAG00000023789, Expressed in articular cartilage of joint and 23 other tissues |
ExpressionAtlasi | F6Z4X1, baseline |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 252 – 320 | DisorderedSequence analysisAdd BLAST | 69 | |
Regioni | 367 – 404 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 448 – 471 | DisorderedSequence analysisAdd BLAST | 24 | |
Regioni | 498 – 600 | DisorderedSequence analysisAdd BLAST | 103 | |
Regioni | 657 – 706 | DisorderedSequence analysisAdd BLAST | 50 | |
Regioni | 1022 – 1053 | DisorderedSequence analysisAdd BLAST | 32 | |
Regioni | 1100 – 1209 | DisorderedSequence analysisAdd BLAST | 110 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 252 – 299 | PolarSequence analysisAdd BLAST | 48 | |
Compositional biasi | 498 – 558 | PolarSequence analysisAdd BLAST | 61 | |
Compositional biasi | 566 – 587 | PolarSequence analysisAdd BLAST | 22 | |
Compositional biasi | 657 – 679 | PolarSequence analysisAdd BLAST | 23 | |
Compositional biasi | 1100 – 1124 | PolarSequence analysisAdd BLAST | 25 | |
Compositional biasi | 1141 – 1158 | PolarSequence analysisAdd BLAST | 18 | |
Compositional biasi | 1159 – 1173 | Pro-richSequence analysisAdd BLAST | 15 |
Keywords - Domaini
RepeatARBA annotation, WD repeatPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00390000016223 |
HOGENOMi | CLU_008882_0_0_1 |
InParanoidi | F6Z4X1 |
OMAi | PPAECCQ |
OrthoDBi | 488527at2759 |
TreeFami | TF328981 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
SMARTi | View protein in SMART SM00320, WD40, 3 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 1 hit PS50294, WD_REPEATS_REGION, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6Z4X1-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKVVPEKNAV RILWGRERGT RAFGAQRLLQ ELVEDKTRWM KWEGKRVELP
60 70 80 90 100
DSPRSTFLLA FSPDRTLLAS THVNHNIYIT EVKTGKCVHS LIGHRRTPWC
110 120 130 140 150
VTFHPTISGL IASGCLDGEV RIWDLHGGSE SWFTDSNNAI ASLAFHPTAQ
160 170 180 190 200
LLLIATANEI HFWDWSRREP FAVVKTASDM ERVRLVRFDP LGHYLLTAIV
210 220 230 240 250
NPSNQQGDDE PEIPIDGTEL SHYRQRALLQ SQPVRRTPLL HNFLHMLSSR
260 270 280 290 300
SSGIQTEPFH PPEQASSTQQ DQGLLNRPSA FSTVQSSTAG NTLRNLSLGP
310 320 330 340 350
TRRSLGGPLS SHPSRYHREI APGLTGSEWT RTVLSLNSRC EAESMPPPRT
360 370 380 390 400
SASSVSLLSV LRQQEGGSQA SVYTSATEGR GFPASGLAAE SDGGNGSSQN
410 420 430 440 450
NSGSIRHELQ CDLRRFFLEY DRLQELDQSL SGEAPQNQQA QEMLNNNIES
460 470 480 490 500
ERPGPSHQPT PHSSENNSNL SRGHLNRCRA CHNLLTFNND TLRWERTTPN
510 520 530 540 550
YSSGEASSSW QVPSTFEGMP SSGSQLPPLE RTEGQTPSSS RLELSSSASP
560 570 580 590 600
QEERTVGVAF NQETGHWERI YTQSSRSGTV SQEALHQDMP EESSEEDSLR
610 620 630 640 650
RRLLESSLIS LSRYDGAGSR EHPIYPDPAR LSPAAYYAQR MIQYLSRRDS
660 670 680 690 700
IRQRSMRYQQ NRLRSSTTSS SSDNQGPSVE GTDLEFEDFE DNGDRSRHRA
710 720 730 740 750
PRNARMSAPS LGRFVPRRFL LPEYLPYAGI FHERGQPGLA THSSVNRVLA
760 770 780 790 800
GAVIGDGQSA VASNIANTTY RLQWWDFTKF DLPEISTASV NVLVQNCKIY
810 820 830 840 850
NDASCDISAD GQLLAAFIPS SQRGFPDEGI LAVYSLAPHN LGEMLYTKRF
860 870 880 890 900
GPNAISVSLS PMGRYVMVGL ASRRILLHPS TEHMVAQVFR LQQAHGGETS
910 920 930 940 950
MRRVFNVLYP MPADQRRHVS INSARWLPEP GLGLAYGTNK GDLVICRPEA
960 970 980 990 1000
LNSGVEYYWD QLNETVFTVH SNSRSSERPG TSRATWRTDR DMGLMNAIGL
1010 1020 1030 1040 1050
QPRNPTTSVT SQGTQTLALQ LQNAETQTER EIQEPGTAAS GPGEGEGSEY
1060 1070 1080 1090 1100
GAGGEDALSR IQRLMAEGGM TAVVQREQST TMASMGGFGN NIIVSHRIHR
1110 1120 1130 1140 1150
SSQTGTEPGA ARATSPQPST SRGLLPEPGQ LAERGLSPRT ASWDQPGTPG
1160 1170 1180 1190 1200
REPSQPTLLS SSPVPPPVPL PSTEGPTLHC ELTSTRHLPD GGGSSRGEAA
GPSGEPRNR
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q2HHC0 | A0A3Q2HHC0_HORSE | Autophagy and beclin 1 regulator 1 | AMBRA1 | 1,299 | Annotation score: |
Sequence databases
RefSeqi | XP_001489841.1, XM_001489791.4 |
Genome annotation databases
Ensembli | ENSECAT00000025776; ENSECAP00000021459; ENSECAG00000023789 |
GeneIDi | 100050652 |
KEGGi | ecb:100050652 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_001489841.1, XM_001489791.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6Z4X1 |
Genome annotation databases
Ensembli | ENSECAT00000025776; ENSECAP00000021459; ENSECAG00000023789 |
GeneIDi | 100050652 |
KEGGi | ecb:100050652 |
Organism-specific databases
CTDi | 55626 |
VGNCi | VGNC:15273, AMBRA1 |
Phylogenomic databases
GeneTreei | ENSGT00390000016223 |
HOGENOMi | CLU_008882_0_0_1 |
InParanoidi | F6Z4X1 |
OMAi | PPAECCQ |
OrthoDBi | 488527at2759 |
TreeFami | TF328981 |
Gene expression databases
Bgeei | ENSECAG00000023789, Expressed in articular cartilage of joint and 23 other tissues |
ExpressionAtlasi | F6Z4X1, baseline |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
InterProi | View protein in InterPro IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
SMARTi | View protein in SMART SM00320, WD40, 3 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 1 hit PS50082, WD_REPEATS_2, 1 hit PS50294, WD_REPEATS_REGION, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6Z4X1_HORSE | |
Accessioni | F6Z4X1Primary (citable) accession number: F6Z4X1 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 58 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |