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Protein
Submitted name:

Aurora kinase A

Gene

AURKA

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Aurora kinase AImported
Gene namesi
Name:AURKAImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 22

Organism-specific databases

VGNCiVGNC:15703 AURKA

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF6YZI7

Expressioni

Gene expression databases

BgeeiENSECAG00000023961

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000021467

Structurei

3D structure databases

ProteinModelPortaliF6YZI7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini133 – 383Protein kinaseInterPro annotationAdd BLAST251

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0580 Eukaryota
ENOG410XNRB LUCA
GeneTreeiENSGT00910000144066
InParanoidiF6YZI7
KOiK11481
OMAiQATSVPH
OrthoDBiEOG091G0EU2
TreeFamiTF105331

Family and domain databases

CDDicd14116 STKc_Aurora-A, 1 hit
InterProiView protein in InterPro
IPR030616 Aur
IPR030611 AURKA
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR24350 PTHR24350, 1 hit
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

F6YZI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRSKENCIS GPVKTTVPLG DGPKRVPVTQ QLPQNLLSAN SGQAQRVLCP
60 70 80 90 100
SNSSHRVPSQ AQKLVSSHKP VQNLKQKQSQ ATSVPHPVPR PLNNTQRSEQ
110 120 130 140 150
LQPSAPGNNS EKELASKEKN EESKKRQWAL EDFEIGRPLG KGKFGNVYLA
160 170 180 190 200
REKQSKFILA LKVLFKAQLE KAGVEHQLRR EVEIQSHLRH PNILRLYGYF
210 220 230 240 250
HDATRVYLIL EYAPLGAVYR ELQKLSKFDE QRTATYITEL ANALAYCHSK
260 270 280 290 300
RVIHRDIKPE NLLLGSAGEL KIADFGWSVH APSSRRTTLC GTLDYLPPEM
310 320 330 340 350
IEGRMHDEKV DLWSLGVLCY EFLVGKPPFE ASTYQETYKR ISRVEFTFPD
360 370 380 390 400
FVPEGARDLI SRLLKHNPSQ RPTLKEVLEH PWITANSSKP SNSQKSKEST

SKQP
Length:404
Mass (Da):45,741
Last modified:July 27, 2011 - v1
Checksum:iD9C5C2DC77FC0836
GO

Sequence databases

RefSeqiXP_001489320.1, XM_001489270.5

Genome annotation databases

EnsembliENSECAT00000025786; ENSECAP00000021467; ENSECAG00000023961
GeneIDi100050161
KEGGiecb:100050161

Similar proteinsi

Entry informationi

Entry nameiF6YZI7_HORSE
AccessioniPrimary (citable) accession number: F6YZI7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: March 28, 2018
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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