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Entry version 42 (12 Aug 2020)
Sequence version 3 (11 Dec 2019)
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Protein
Submitted name:

Sperm associated antigen 17

Gene

SPAG17

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Sperm associated antigen 17Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SPAG17Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEquus caballus (Horse)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9796 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002281 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Vertebrate Gene Nomenclature Database

More...
VGNCi
VGNC:23474, SPAG17

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6YQY1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSECAG00000024156, Expressed in oviduct epithelium and 5 other tissues

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni141 – 208DisorderedSequence analysisAdd BLAST68
Regioni656 – 760DisorderedSequence analysisAdd BLAST105
Regioni885 – 922DisorderedSequence analysisAdd BLAST38
Regioni952 – 978DisorderedSequence analysisAdd BLAST27
Regioni1085 – 1114DisorderedSequence analysisAdd BLAST30
Regioni1177 – 1211DisorderedSequence analysisAdd BLAST35
Regioni1316 – 1373DisorderedSequence analysisAdd BLAST58
Regioni1954 – 1977DisorderedSequence analysisAdd BLAST24

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1889 – 1909Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi141 – 187PolyampholyteSequence analysisAdd BLAST47
Compositional biasi692 – 707PolarSequence analysisAdd BLAST16
Compositional biasi708 – 723PolyampholyteSequence analysisAdd BLAST16
Compositional biasi724 – 745PolarSequence analysisAdd BLAST22
Compositional biasi888 – 907PolarSequence analysisAdd BLAST20
Compositional biasi908 – 922PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1181 – 1211PolyampholyteSequence analysisAdd BLAST31
Compositional biasi1336 – 1353PolarSequence analysisAdd BLAST18

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000013693

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001433_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6YQY1

TreeFam database of animal gene trees

More...
TreeFami
TF328540

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026173, SPAG17

The PANTHER Classification System

More...
PANTHERi
PTHR21963, PTHR21963, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

F6YQY1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAPKKEKSGS ASANSKIWEP SLIAAHFNQN DWKGVIAFVV GNRIEDELLI
60 70 80 90 100
GALTLAVQAP QRRLFSMVSW QDILQQINGT NALPGTASKK GKKPLGGSAP
110 120 130 140 150
LYSEVLIATK AIMDSGEKLT LPLIGKLLKY QLLQIKYKDQ QRRESEKKVT
160 170 180 190 200
EDKFKTEKDK GKAKSPKEKK PSGTKVVKGK GKDQPEANTT VKKATQLKQR
210 220 230 240 250
GEEDDAKRYI DDEPDDGAQH YIIVVGFNDP QLLAIMTELG IPISSVIKIS
260 270 280 290 300
SENYEPLQAH LAAVSQQQEV SLQPEDIEAE KLKNENTIKE LEIFWKYLEP
310 320 330 340 350
ILNNEKPETN LFDVARLEYM VKEDGFPSDW SDSGMMLELG TDIFENIACL
360 370 380 390 400
MYDSLDWKRQ HRHYLESMQL INVPQVVNEK PILEAVAIAE APQAAAPTPG
410 420 430 440 450
KKKAQNEERQ APTSVPFVIT TEADMRYYND LLNPIPEEFI SVPLILHCML
460 470 480 490 500
EQVVATEEDL VPPSLVEPPP RADGLDHRIA AHIVSILPSL CLTEKEKKNL
510 520 530 540 550
QEIFLSEEEN ESKAVPKGPL LLNYHDTLAH KKYALKDPKN FDPVQIEQEM
560 570 580 590 600
QSKLPLWEFL EFPLPPPWNS TKRLATIHEL MHFCTNEVLS WNEVERAFKV
610 620 630 640 650
FTFESLKLST VDEKGKLKPA RMMYGTDCEM FNIPWDNPAR FAKQIRQQYI
660 670 680 690 700
TKMNTQEVKQ KTDTETKDRI LFVDQNMPVS VQDDESSKEP SDPSQADASN
710 720 730 740 750
MQHSDSNNKK SLDPDDRELS EQDNSLKTQL QSEPLEQTTG NEIKDEAVTN
760 770 780 790 800
VDPPEKKSKK MTVEAELEDI KKTEQRSLMD WSFTEHFKPK VLLQVLQEAN
810 820 830 840 850
QHYRCIDSYY HTQDNSLLLV FHNPMNLQRL HCEYWNVALH SNVGFRNYLE
860 870 880 890 900
LVAQSIQDWI IKEEAIYQES KMAEELSRSK LEQEVKSPAS GKISSPSKIY
910 920 930 940 950
SVKKSKSNKG MSKTELIDQE KEKEKEKEKI PFILEGSLKA WKEEQDRLAE
960 970 980 990 1000
EERLKEEKKA EKKSKDIGKK KGKEKVERED SRVLKKKSFF KDKAKEEQIK
1010 1020 1030 1040 1050
ISDVTEEPLQ QPEPEIVYPF RGYNMGDIPI QISGTNCYLY PSDGGQIEVE
1060 1070 1080 1090 1100
KTTFEKGPTF IKVKVKKDKH NFIIHLKDPK KIVRNEKKED DYSSEDEKDE
1110 1120 1130 1140 1150
GEEERNLEMK ESDAENKAIS KFGSFSATLE NGICLSISYY GSSGMAPEDK
1160 1170 1180 1190 1200
DPNLEAMLNI PSALTPTIIP VVVTVPQGKG KGKTKGKEKP KDSIKEEEHP
1210 1220 1230 1240 1250
KEEEKKEEVE PEPVLQETVY VPTFQNLNVS CPSGLLVTFI GQESAGHHVM
1260 1270 1280 1290 1300
DEEPTWDIMV RQSYPQKVKH YEFYKTVMPP VEQEASRVIT SQGTVVKYML
1310 1320 1330 1340 1350
DGSTQILFAN GAVSSSPDSG PVCPPPEMPA SPHNGDLMDS VSQQKSETAP
1360 1370 1380 1390 1400
SETVITKKGK GHKNQSSVPH TNEIHEPPQE VVQIVTPVEV HVGTWFTTTP
1410 1420 1430 1440 1450
DGNRIGTKGL EKIADLAPFL SFQATDPVNG TVMTTREDKV IIVEKKDGTR
1460 1470 1480 1490 1500
IVDHADGTRI TTFYQVYEDH IMPPDDQEIP EHPQTLTRQV KCMRIESSHY
1510 1520 1530 1540 1550
ATVITNCEDS SCCATFGDGT SIIAKPQGTY QVLPSNKGCL HIDRDCSAVY
1560 1570 1580 1590 1600
YHESSSDIYH PFQKREQLRA SRYIMKHTSE VLCEVLDPEG NTFQVMADGS
1610 1620 1630 1640 1650
TSTLLPENNL EDDLNSKPEG YDSLSSTHLH KNHLQIYGEH VPRFFVIYAD
1660 1670 1680 1690 1700
GSGVELLRDD DIEEYLSLAY GESTTVVLQE PVQEQPGALS ITVLRPFHEA
1710 1720 1730 1740 1750
SPWLMKKELD TIVPPNLQSR SWEKFPSVEK KTPGPPFGTH IWKGLNIECK
1760 1770 1780 1790 1800
QLVSAPAPIL KSPNVLQIRQ FIQHEVINDE VKLKLQISLK DYINHILKKE
1810 1820 1830 1840 1850
DELQEMTVKD SRTEEERGNA ADLLKLVMSF PKMEETTKGH ATEVAAHLVD
1860 1870 1880 1890 1900
LFKQSLAVAP ECPPETFDTD FLEKKGRHIA SEKRWKEKID QKRKEIEKTH
1910 1920 1930 1940 1950
NYLEEIRNRT VSPYFKSELS KTFQSQFNYL DALSKNLPPF TKKVEDTNKT
1960 1970 1980 1990 2000
AVQNTSNLQP DSQPNKVSQQ ESSDTLSLPK SEAFVDMKAF ASQNQTENLT
2010 2020 2030 2040 2050
KSTEEPETYA PVKIPTQSLL QDVAGQARKE KVRLPRYLLS SKPKSQPLEK
2060 2070 2080 2090 2100
VQDSVGGRVR TSSVASAAIN NANSSPFGFH LLPPSVNFGV LEEGHTYETT
2110 2120 2130 2140 2150
VKLKNVGVDF CRFRVKQPPP STGLKVTYKP GPMVTDMQAE LKVELFTMVV
2160 2170 2180 2190 2200
GEDGAKGSAH ISHNIEIMTE HDVLFLPVEA TVLTSSNYDK RLKDFPQEKE
2210 2220
NPTIQRTSTI SSAKLGVFMS RKVSPY
Length:2,226
Mass (Da):251,664
Last modified:December 11, 2019 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6DD1AC7B9C6B4DA6
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSECAT00000026060; ENSECAP00000021711; ENSECAG00000024156

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PaxDbiF6YQY1

Genome annotation databases

EnsembliENSECAT00000026060; ENSECAP00000021711; ENSECAG00000024156

Organism-specific databases

VGNCiVGNC:23474, SPAG17

Phylogenomic databases

GeneTreeiENSGT00390000013693
HOGENOMiCLU_001433_0_0_1
InParanoidiF6YQY1
TreeFamiTF328540

Gene expression databases

BgeeiENSECAG00000024156, Expressed in oviduct epithelium and 5 other tissues

Family and domain databases

InterProiView protein in InterPro
IPR026173, SPAG17
PANTHERiPTHR21963, PTHR21963, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6YQY1_HORSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6YQY1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: August 12, 2020
This is version 42 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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