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Protein
Submitted name:

Arginyl-tRNA synthetase

Gene

RARS

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Arginyl-tRNA synthetaseImported
Gene namesi
Name:RARSImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 14

Organism-specific databases

VGNCiVGNC:22188 RARS

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF6YPN7

Expressioni

Gene expression databases

BgeeiENSECAG00000024383

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000021990

Structurei

3D structure databases

ProteinModelPortaliF6YPN7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini76 – 164Arg_tRNA_synt_NInterPro annotationAdd BLAST89
Domaini532 – 658DALR_1InterPro annotationAdd BLAST127

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili5 – 32Sequence analysisAdd BLAST28
Coiled coili41 – 61Sequence analysisAdd BLAST21
Coiled coili461 – 481Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG1195 Eukaryota
COG0018 LUCA
GeneTreeiENSGT00530000063407
InParanoidiF6YPN7
KOiK01887
OMAiNKPLHLG
OrthoDBiEOG091G03A6
TreeFamiTF106111

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

F6YPN7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGLVAQCSA RLLQQEKEIK SLTAEIDQLK NCGCLEASPN LEQLREENLK
60 70 80 90 100
LKYRLNILRK SLQAERNRPT MININSRLQE VFGCAIKAAY PDLENPPLIV
110 120 130 140 150
TPSQQPKFGD YQCNSAMGIS QMLKSKEQKV NPREIAENIT KHLPGNECIE
160 170 180 190 200
KVEIAGPGFI NVHLRKDFVS EQLTSLLVNG VQLPALGENK KVVVDFSSPN
210 220 230 240 250
IAKEMHVGHL RSTIIGESMC RLFEFAGYDV LRLNHLGDWG TQFGMLIAHL
260 270 280 290 300
QDKFPDYLTV SPPIGDLQAF YKESKKRFDT EEEFKKRAYQ CVVLLQSKNP
310 320 330 340 350
DITKAWKLIC DVSRQEFNKI YDALDISLIE RGESFYQDRM NDIVKEFEDR
360 370 380 390 400
GFVQVDDGRK IVFVPGCSIP LTIVKSDGGY TYDTSDLAAI KQRLFEEKAD
410 420 430 440 450
MIIYVVDNGQ SVHLQTIFAA AQMIGWYDPK VTRVSHAGFG VVLGEDKKKF
460 470 480 490 500
KTRSGETVRL IDLLEEGLKR SMDKLREKER DKVLTAEELK AAQTSVAYGC
510 520 530 540 550
IKYADLSHNR LNDYIFSFDK MLDDRGNTAA YLLYAFTRIR SIARLANIDE
560 570 580 590 600
EMLQKAARET KIILDHEKEW KLGRCILRFP EILQKILDDL FLHTLCDYIY
610 620 630 640 650
ELATTFTEFY DSCYCVEKDR QTGKVLKVNM WRMLLCEAVA AVMAKGFDIL

GIKPVQRM
Length:658
Mass (Da):75,200
Last modified:July 27, 2011 - v1
Checksum:i04E90BA2BA4F0567
GO

Sequence databases

RefSeqiXP_001503321.1, XM_001503271.4

Genome annotation databases

EnsembliENSECAT00000026369; ENSECAP00000021990; ENSECAG00000024383
GeneIDi100059383
KEGGiecb:100059383

Similar proteinsi

Entry informationi

Entry nameiF6YPN7_HORSE
AccessioniPrimary (citable) accession number: F6YPN7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: May 23, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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