UniProtKB - F6YN77 (F6YN77_HORSE)
Protein
Submitted name:
Adhesion G protein-coupled receptor G2
Gene
ADGRG2
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- G protein-coupled receptor activity Source: GO_Central
GO - Biological processi
- adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
- cell surface receptor signaling pathway Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Adhesion G protein-coupled receptor G2Imported |
Gene namesi | Name:ADGRG2Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:15108, ADGRG2 |
Subcellular locationi
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 605 – 633 | HelicalSequence analysisAdd BLAST | 29 | |
Transmembranei | 645 – 668 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 680 – 703 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 715 – 736 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 764 – 793 | HelicalSequence analysisAdd BLAST | 30 | |
Transmembranei | 814 – 834 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 840 – 862 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSECAG00000023252, Expressed in articular cartilage of joint and 12 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 547 – 598 | GPSInterPro annotationAdd BLAST | 52 | |
Domaini | 608 – 863 | G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST | 256 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 259 – 343 | DisorderedSequence analysisAdd BLAST | 85 | |
Regioni | 898 – 919 | DisorderedSequence analysisAdd BLAST | 22 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 264 – 280 | Pro-richSequence analysisAdd BLAST | 17 | |
Compositional biasi | 281 – 343 | PolarSequence analysisAdd BLAST | 63 |
Keywords - Domaini
SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000156341 |
HOGENOMi | CLU_002753_3_3_1 |
InParanoidi | F6YN77 |
TreeFami | TF321769 |
Family and domain databases
InterProi | View protein in InterPro IPR017981, GPCR_2-like IPR000832, GPCR_2_secretin-like IPR017983, GPCR_2_secretin-like_CS IPR000203, GPS |
Pfami | View protein in Pfam PF00002, 7tm_2, 1 hit PF01825, GPS, 1 hit |
PRINTSi | PR00249, GPCRSECRETIN |
SMARTi | View protein in SMART SM00303, GPS, 1 hit |
PROSITEi | View protein in PROSITE PS00650, G_PROTEIN_RECEP_F2_2, 1 hit PS50261, G_PROTEIN_RECEP_F2_4, 1 hit PS50221, GPS, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All
F6YN77-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MFFFGGHCSH VGRPEELLLT FKIFLVIICL HFVLVTSLEE NADNSSLLSP
60 70 80 90 100
SDATSSVLST LNKTEKTKIT IVKTFNASGV KPQRNICNLS SICNDSAFFR
110 120 130 140 150
GEIMFQYDEE SNVTENQNMA NGTLTGVLSL SELKRSELNK TLQALSETYF
160 170 180 190 200
IVCATAEAQS TLNCTFTVKL NKTVNICAAM VALKKVNIRP MEQCCCSVRT
210 220 230 240 250
PCPSSPEELE KLQCDLQDPI VCLASHPHGP PFYSSSNSIP VAPQATILSQ
260 270 280 290 300
VSSTFSFAEP LDQPPVTQSP PSPTGVIHLP SPQPSTPIAS SAATDMPLQS
310 320 330 340 350
GTLSSPIPQT DLSHTLPPVK SSLPSPTTSA PVNVITTSTP PDKTEIVHNS
360 370 380 390 400
SISVSDLENQ VSQMEKALSL GSLEPNLAEE MINQVSKLLR SPPALLAPLA
410 420 430 440 450
QRLLKVVDDI GLQLNFSTKT ISLTSPSLAL AVIRVNASNF DTTTFAAQDP
460 470 480 490 500
ENLQVSLETQ APENSIGVIT LPSSLMSNLP ANDVELASRV QFNFFETPAL
510 520 530 540 550
FQDPALENLS LISYVISSSV ANLTVKNLTR NVTVTLKHID PSQDDLTVRC
560 570 580 590 600
VFWDLGRNGG RGGWSSDGCS VKDRRLNETI CTCSHLTSFG VLLDLSRTSL
610 620 630 640 650
PPAQMMALTF ITYIGCGLSS IFLSVTLVTY IAFEKIRRDY PSKILIQLCA
660 670 680 690 700
ALLLLNLVFL LDSWIALYDM RGLCISVAVF LHYFLLVSFT WMGLEAFHMY
710 720 730 740 750
LALVKVFNTY IRKYILKFCI VGWGVPAVVV TIVLIISPDN YGLGSYGKFP
760 770 780 790 800
NGSPDDFCWI NSNAVFYITV VGYFCVIFLL NVSMFIVVLV QLCRIKKKKQ
810 820 830 840 850
LGAQRKTSIQ DLRSVAGLTF LLGITWGFAF FAWGPVNVTF MYLFAIFNTL
860 870 880 890 900
QGFFIFIFYC VAKENVRKQW RRYLCCGKLR LAENSDWSKT ATNGLKKQTV
910 920 930 940 950
NQGVSSSSNS LQSNSNSTHS TTLLVNNDCS GLSSGNGNAS TDKNGVSFSV
960 970 980 990
QNGDVCLHDF TGKQHMFNER EDSCNGKSRI ALRRTSKRGS LHFIEQM
Computationally mapped potential isoform sequencesi
There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A5F5PG86 | A0A5F5PG86_HORSE | Adhesion G protein-coupled receptor... | ADGRG2 | 1,021 | Annotation score: | ||
A0A5F5PFL6 | A0A5F5PFL6_HORSE | Adhesion G protein-coupled receptor... | ADGRG2 | 970 | Annotation score: | ||
A0A5F5PM46 | A0A5F5PM46_HORSE | Adhesion G protein-coupled receptor... | ADGRG2 | 1,007 | Annotation score: | ||
A0A5F5PME1 | A0A5F5PME1_HORSE | Adhesion G protein-coupled receptor... | ADGRG2 | 1,005 | Annotation score: | ||
A0A5F5PTY2 | A0A5F5PTY2_HORSE | Adhesion G protein-coupled receptor... | ADGRG2 | 902 | Annotation score: | ||
A0A5F5PZL6 | A0A5F5PZL6_HORSE | Adhesion G protein-coupled receptor... | ADGRG2 | 999 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000025533; ENSECAP00000021240; ENSECAG00000023252 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6YN77 |
Genome annotation databases
Ensembli | ENSECAT00000025533; ENSECAP00000021240; ENSECAG00000023252 |
Organism-specific databases
VGNCi | VGNC:15108, ADGRG2 |
Phylogenomic databases
GeneTreei | ENSGT00940000156341 |
HOGENOMi | CLU_002753_3_3_1 |
InParanoidi | F6YN77 |
TreeFami | TF321769 |
Gene expression databases
Bgeei | ENSECAG00000023252, Expressed in articular cartilage of joint and 12 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR017981, GPCR_2-like IPR000832, GPCR_2_secretin-like IPR017983, GPCR_2_secretin-like_CS IPR000203, GPS |
Pfami | View protein in Pfam PF00002, 7tm_2, 1 hit PF01825, GPS, 1 hit |
PRINTSi | PR00249, GPCRSECRETIN |
SMARTi | View protein in SMART SM00303, GPS, 1 hit |
PROSITEi | View protein in PROSITE PS00650, G_PROTEIN_RECEP_F2_2, 1 hit PS50261, G_PROTEIN_RECEP_F2_4, 1 hit PS50221, GPS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6YN77_HORSE | |
Accessioni | F6YN77Primary (citable) accession number: F6YN77 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | August 12, 2020 | |
This is version 52 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |