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Entry version 54 (07 Oct 2020)
Sequence version 2 (11 Dec 2019)
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Protein

DNA polymerase zeta catalytic subunit

Gene

rev3l

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

[4Fe-4S] clusterARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-directed DNA polymeraseARBA annotation, Nucleotidyltransferase, Transferase
Ligand4Fe-4SARBA annotation, Iron, Iron-sulfur, Metal-binding, ZincARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA polymerase zeta catalytic subunitARBA annotation (EC:2.7.7.7ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rev3lImported
Synonyms:etv6Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8364 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008143 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-853923, etv6
XB-GENE-1012630, rev3l

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
F6YLS4

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSXETG00000008919, Expressed in gastrula and 11 other tissues

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
8364.ENSXETP00000019556

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini46 – 189DNA_pol_B_exo1InterPro annotationAdd BLAST144
Domaini739 – 1110DUF4683InterPro annotationAdd BLAST372
Domaini2201 – 2420DNA_pol_B_exo1InterPro annotationAdd BLAST220
Domaini2487 – 2936DNA_pol_BInterPro annotationAdd BLAST450
Domaini2978 – 3045zf-C4polInterPro annotationAdd BLAST68

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni268 – 293DisorderedSequence analysisAdd BLAST26
Regioni469 – 500DisorderedSequence analysisAdd BLAST32
Regioni905 – 935DisorderedSequence analysisAdd BLAST31
Regioni1012 – 1040DisorderedSequence analysisAdd BLAST29
Regioni1140 – 1235DisorderedSequence analysisAdd BLAST96
Regioni1255 – 1279DisorderedSequence analysisAdd BLAST25
Regioni1408 – 1435DisorderedSequence analysisAdd BLAST28
Regioni1524 – 1583DisorderedSequence analysisAdd BLAST60
Regioni1657 – 1680DisorderedSequence analysisAdd BLAST24
Regioni1790 – 1830DisorderedSequence analysisAdd BLAST41
Regioni2045 – 2136DisorderedSequence analysisAdd BLAST92

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi268 – 283PolyampholyteSequence analysisAdd BLAST16
Compositional biasi473 – 489PolyampholyteSequence analysisAdd BLAST17
Compositional biasi911 – 927PolarSequence analysisAdd BLAST17
Compositional biasi1021 – 1035BasicSequence analysisAdd BLAST15
Compositional biasi1156 – 1173PolarSequence analysisAdd BLAST18
Compositional biasi1184 – 1204BasicSequence analysisAdd BLAST21
Compositional biasi1214 – 1230PolarSequence analysisAdd BLAST17
Compositional biasi1794 – 1819PolarSequence analysisAdd BLAST26
Compositional biasi2046 – 2095PolarSequence analysisAdd BLAST50
Compositional biasi2111 – 2125PolarSequence analysisAdd BLAST15

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DNA polymerase type-B family.ARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3804, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156226
ENSGT00940000159508

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_037998_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
F6YLS4

TreeFam database of animal gene trees

More...
TreeFami
TF318679

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.132.60, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006172, DNA-dir_DNA_pol_B
IPR017964, DNA-dir_DNA_pol_B_CS
IPR006133, DNA-dir_DNA_pol_B_exonuc
IPR006134, DNA-dir_DNA_pol_B_multi_dom
IPR043502, DNA/RNA_pol_sf
IPR042087, DNA_pol_B_C
IPR023211, DNA_pol_palm_dom_sf
IPR032757, DUF4683
IPR030559, PolZ_Rev3
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR025687, Znf-C4pol

The PANTHER Classification System

More...
PANTHERi
PTHR45812, PTHR45812, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00136, DNA_pol_B, 1 hit
PF03104, DNA_pol_B_exo1, 2 hits
PF15735, DUF4683, 1 hit
PF14260, zf-C4pol, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00106, DNAPOLB

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00486, POLBc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00116, DNA_POLYMERASE_B, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

F6YLS4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFFLRLVTAD YYLAAPLPGL DVTRSHFRDG PVRRVPVVRV FGATPAGQRA
60 70 80 90 100
CLHLHGIFPY LYTPYDGYGQ QDPERYLRQI AFSIDRALNV ALGNPSANSQ
110 120 130 140 150
HVFKITVVSG VPFYGYHEKE RQFMKIYLYN PVMVKRVSEL LQGGAVMNKC
160 170 180 190 200
YQSHEAHVPY LLQLFIDYNL YGMNLINLAA VKFRRVQRKD GSFHGTGLHK
210 220 230 240 250
DIDQQRSLSG TFVRWEEDEI PSSLLLEDVE PISTCELEVD GVAADILNRQ
260 270 280 290 300
EIEAQIGKNP GLQAIWEDEK QRRRERRESS QISPPDSQDR GFVAVSESEK
310 320 330 340 350
ILQKRLKEIL KQNDFSLTLP HSLDCSNISE EFSVELTLHS QLESPEVVLC
360 370 380 390 400
SQANMVDVHR DEPQNKGCVD EEQEDAVIDE EAILNIMETS QIFQSQRLSQ
410 420 430 440 450
SPVFLDDNQD EAMVKLLAGL EDDGYQMDMS RRLSQHSFSA RYNSMQNSDD
460 470 480 490 500
EENEPQVEKE EMELSMLMSQ RWDNNTEERD TKRNIEESSP EDEDSTDDEM
510 520 530 540 550
EWSRNRLLLA DLSIPQLDGT ADENSDNPLN NESTLTHSFV IAKSKLPLKN
560 570 580 590 600
SVFHKDAASF EPQSSAKTAF QCQHTSALSS HILKKEGLIE ELPEPAEEKG
610 620 630 640 650
PELSVHSFQN DSTYSMKYPA SFNNSTSPEL LHKEVSKNDI TIAASDKTAF
660 670 680 690 700
EDGIPLVNRH LQCRKFTSIR KTDKDTSFLK LTRQLSEGTL DRNPRNLIEL
710 720 730 740 750
SNHKMKRSLD TNEKCCNSTT NKIFSGTVNE SNDLTPSVDV SRVILHTADS
760 770 780 790 800
AINDVSPNKR KVRSEELQEH TTDMSSGNQQ VTHYKFFPSV VLSNCLNRPQ
810 820 830 840 850
KLAPVTYKVQ QCKKQSRLKL GSVEYREKKP LQKQTIDAVN VNALVKDIPS
860 870 880 890 900
CDMAVMMGDG AFQSNACELN SFASQFEEGA TDSEPCLEIC GNKYTLRGKR
910 920 930 940 950
KVHFESEDGE PVQGATNSKS SLLQPEEATD EVENVQKVRK RRKVSNKLPP
960 970 980 990 1000
VIIKYIIINR FKGRKNMLVK LEKLDPSEEQ VRLTEDNIKL YNRMAPLKDF
1010 1020 1030 1040 1050
WPKVPESPAT KYPILPITPK KNNRRKTKQK SVKKKPGRLP KTETKVLKRA
1060 1070 1080 1090 1100
IPVRRKRIRS FLSLPIPTYN AETDDCGTDY KDVMSKLGFL VERCPSPINM
1110 1120 1130 1140 1150
SPPRCWSPTD PRAEEMMATP IADMPLFKSP LLVDSNKVHG ISMKKQQKRI
1160 1170 1180 1190 1200
NKSRKKIATS PSALRNQPKK ISQPNMGKDG KKQKGKSGSK KSEKAPRKHT
1210 1220 1230 1240 1250
KIKDKDKKTN AEPRVSEQSS LPQKEHMAST LNGAVQPVPV ITRDFTLSGF
1260 1270 1280 1290 1300
STGHVHSTQL PTDSSTQNDS PGNINSFTGT TTPLHFQQFS SIPKDCSASA
1310 1320 1330 1340 1350
FVPLSPAIKT FSINAVKPQF PNAFQVKESS ATQNTTQNSF TRSPQVIQNA
1360 1370 1380 1390 1400
QFTLNSSLTT REDAAEVQKR LLASAGKLHD VQNSPNSLAS EKFQPKLFPC
1410 1420 1430 1440 1450
SFKHSGNLAD TSKNSDSNTP VTSSEEGHEA LNSPNSSVVT CLKMTALEQK
1460 1470 1480 1490 1500
QRGDSFDAAQ FATQRVNQNC LPEIFSCTKG IQNTMKSVSP QALLDAHSGI
1510 1520 1530 1540 1550
AVLKELLHKK QQKVSLSRDE STVKLKLSLS GPSEPKSIKS ATHGKKTRTP
1560 1570 1580 1590 1600
RSAKSKVANN VKTETGKHLS DSESKNYIPE RSPGLFSDPS FESCYSIEDS
1610 1620 1630 1640 1650
LSPEHNYNFD INAVGQTGLC TLYSGSQFIP ADQNLPQKFL SDPSPLPASD
1660 1670 1680 1690 1700
NECLNHELQQ SEKKKPRSLG HPLLRPSSLS PDMFEKSVEF KQNPLLNQWK
1710 1720 1730 1740 1750
NCLLSQNNHH THPVDGFYNC QSEDKYRLNR SISLKDVTFN FAHTEWAQTG
1760 1770 1780 1790 1800
IKHTMFDASL PPNSNSSFTG LLPSPEGDIV SDDLELYISR HSGGLTPTPD
1810 1820 1830 1840 1850
SSPRSINSPS QSKNGNSTPR PVHILKPLMS PPSREEIMAT LLDHDLMETI
1860 1870 1880 1890 1900
YQEPFFSNPS DAPEKPREVG GRVLTVETKL PYNLLEFEGD FSVEGLRFWK
1910 1920 1930 1940 1950
TAFSAMTQNP RPVSPSRVSR LLAERRKDSL SSENDKKLVI MPCKSAPHPQ
1960 1970 1980 1990 2000
RVQVWLQAKE LYETYKTTCK DKEIQEASES KAIETTSVPA GCNSLPPKEI
2010 2020 2030 2040 2050
QILLAQPASS DDLPENIDNI KIHLASPPPV LDSAEKEFVI TACASKPASS
2060 2070 2080 2090 2100
GRSDQNELLD SSVSPDSPVL TSWQETLSPD NTNTAEDNKD FKSGNISPTP
2110 2120 2130 2140 2150
FLECGATPQV KNEPTDLSDL SPSQESRGKL KSKHTCMHST PVIERKPEAE
2160 2170 2180 2190 2200
STEALLCSPL LSEPISQRMS QRRGRNPDKL RRVLLTTQMK NQFATMAQLK
2210 2220 2230 2240 2250
RETSQIEGPS LNNSYGFKVS VQNLQDAKAL HEVQHLTLMS MELHARTRRD
2260 2270 2280 2290 2300
LEPDPEFDPI CALFYCLSSD SLLSNANKKQ VTGAIIVHLE EPSSGRRQTP
2310 2320 2330 2340 2350
FLARSGITGF EVTYAADEKQ LFEMLLSLVR RFDPDILLGY EVQMHSWGYL
2360 2370 2380 2390 2400
LQRASALNVD LCQQLSRVPD DKNENRFSTE KDEYGADTMS EINIVGRIVL
2410 2420 2430 2440 2450
NVWRMMRSEV ALTNYTFENV AFHVLHQRFP LFTFRSLSDW FDNRKDVLRW
2460 2470 2480 2490 2500
RTADYYMCRV HGSLQVLEKL DLIGRTSELA RLFGIQFLHV LTRGSQYRVE
2510 2520 2530 2540 2550
SMMLRIAKPM NYIPLTPSIQ QRSQMRAPQC IPLVMEPESR FYSNCILVLD
2560 2570 2580 2590 2600
FQSLYPSIVI AYNYCYSTCL GNIENLGKYE DFKFGCSSLQ VPPDLLYQLR
2610 2620 2630 2640 2650
HDITVSPNGV AFVKACVRKG VLPRMLEEIL KTRIMVKQSM KKYKHDKGLT
2660 2670 2680 2690 2700
RLLDARQLGL KLIANVTFGY TAANYSGRMP CVEIGDSIVH KARETLERAI
2710 2720 2730 2740 2750
KLVNDTKKWG AKVVYGDTDS MFVLLKGATK EQSFKIGQEI AEAVTATNPK
2760 2770 2780 2790 2800
PIKLKFEKVY LPCVLQTKKR YVGYMYETVD QKDPVFDAKG IETVRRDACP
2810 2820 2830 2840 2850
AVGKILERSL KLLFETRDIS QIKQYVQKQC IKLVEGKASM QDLIFAKEYR
2860 2870 2880 2890 2900
GSFAYKPGAC VPALELTRKM VAYDRRSEPR VGERVPYVII YGSPGVPLIQ
2910 2920 2930 2940 2950
LVRRPIDVLQ DHNLRLNGTY YITKQILPPL NRIFSLIGVD VFSWYDELPR
2960 2970 2980 2990 3000
IQKTFSTARN EQEARKGTIS QYFTTLHCPV CDELTQHGIC SKCRSQPQHV
3010 3020 3030 3040 3050
VVILNQEIRE LEYKQDQLAK LCRNCTGCSN QQIQCVSLNC PVLFKLSRVS
3060
RELCKAPYLR QLLDQF
Length:3,066
Mass (Da):345,724
Last modified:December 11, 2019 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEA38F076C16B2EEB
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A6I8PTL2A0A6I8PTL2_XENTR
DNA polymerase zeta catalytic subun...
rev3l
3,130Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8QKS6A0A6I8QKS6_XENTR
DNA polymerase zeta catalytic subun...
rev3l
3,121Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A6I8RNH1A0A6I8RNH1_XENTR
DNA polymerase zeta catalytic subun...
rev3l
3,025Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSXETT00000019556; ENSXETP00000019556; ENSXETG00000008919
ENSXETT00000092013; ENSXETP00000096298; ENSXETG00000027754

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi8364.ENSXETP00000019556

Proteomic databases

PaxDbiF6YLS4

Genome annotation databases

EnsembliENSXETT00000019556; ENSXETP00000019556; ENSXETG00000008919
ENSXETT00000092013; ENSXETP00000096298; ENSXETG00000027754

Organism-specific databases

XenbaseiXB-GENE-853923, etv6
XB-GENE-1012630, rev3l

Phylogenomic databases

eggNOGiKOG3804, Eukaryota
GeneTreeiENSGT00940000156226
ENSGT00940000159508
HOGENOMiCLU_037998_1_0_1
InParanoidiF6YLS4
TreeFamiTF318679

Gene expression databases

BgeeiENSXETG00000008919, Expressed in gastrula and 11 other tissues

Family and domain databases

Gene3Di1.10.132.60, 1 hit
3.30.420.10, 1 hit
3.90.1600.10, 1 hit
InterProiView protein in InterPro
IPR006172, DNA-dir_DNA_pol_B
IPR017964, DNA-dir_DNA_pol_B_CS
IPR006133, DNA-dir_DNA_pol_B_exonuc
IPR006134, DNA-dir_DNA_pol_B_multi_dom
IPR043502, DNA/RNA_pol_sf
IPR042087, DNA_pol_B_C
IPR023211, DNA_pol_palm_dom_sf
IPR032757, DUF4683
IPR030559, PolZ_Rev3
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR025687, Znf-C4pol
PANTHERiPTHR45812, PTHR45812, 1 hit
PfamiView protein in Pfam
PF00136, DNA_pol_B, 1 hit
PF03104, DNA_pol_B_exo1, 2 hits
PF15735, DUF4683, 1 hit
PF14260, zf-C4pol, 1 hit
PRINTSiPR00106, DNAPOLB
SMARTiView protein in SMART
SM00486, POLBc, 1 hit
SUPFAMiSSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS00116, DNA_POLYMERASE_B, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF6YLS4_XENTR
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: F6YLS4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: December 11, 2019
Last modified: October 7, 2020
This is version 54 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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