UniProtKB - F6YFY8 (F6YFY8_HORSE)
Protein
Submitted name:
Zinc finger protein 317
Gene
ZNF317
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 317Imported |
Gene namesi | Name:ZNF317Imported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:82072, ZNF317 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSECAG00000022001, Expressed in inner cell mass and 22 other tissues |
ExpressionAtlasi | F6YFY8, baseline |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 60 – 132 | KRABInterPro annotationAdd BLAST | 73 | |
Domaini | 193 – 220 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 221 – 248 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 249 – 276 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 277 – 304 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 305 – 332 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 333 – 360 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 361 – 388 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 389 – 416 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 417 – 444 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 445 – 472 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 473 – 500 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 501 – 528 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 529 – 556 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000162241 |
HOGENOMi | CLU_002678_72_0_1 |
InParanoidi | F6YFY8 |
TreeFami | TF338497 |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 9 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 13 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
F6YFY8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAALDLSPTC ALSTQDPACL QESEIPLPSK DRSCPQGVDL FACNGLEPHM
60 70 80 90 100
PTSVGSQESV TFQDVAVDFT EKEWPLLDSS QRKLYKDVML ENYSNLASVD
110 120 130 140 150
WETPSKTKWT ILVEDIFGKE TTNGVTMDRT HLGEKSTGYA HLFEVFTMSA
160 170 180 190 200
HLTQQMGRHT VKRPYHRRDC GVALKNRSHL TQHVSIYNGR KMHECHQCQK
210 220 230 240 250
AFTTSASLTR HRRIHTGEKP YECSACGKAF NDPSALRSHA RTHLTEKPFD
260 270 280 290 300
CSQCGNAFRT LSSLKIHMRV HTGERPYKCD ECGKAYGRSC HLIAHKRTHT
310 320 330 340 350
GERPYECVDC GKAFQHPSHL KEHVRNHTGE KPYECTQCGK AFRWKSNFNL
360 370 380 390 400
HKKNHMVEKT YECKECGKSF GDLLSRRKHM RIHIVKKPVE CRQCGKAFRN
410 420 430 440 450
QSILKTHMNS HTGEKPYGCD LCGKAFSASS NLTAHRKIHT QERRYECAAC
460 470 480 490 500
GKVFGDYLSR RRHMSIHLVK KRVECRQCGK AFRNQSTLKT HMRSHTGEKP
510 520 530 540 550
YECDHCGKAF SIGSNLNVHR RIHTGEKPYE CLACGKAFSD HSSLRSHVKT
560
HRGEKLFASS VWKRLQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A3Q2HSK2 | A0A3Q2HSK2_HORSE | Zinc finger protein 317 | ZNF317 | 598 | Annotation score: |
Genome annotation databases
Ensembli | ENSECAT00000023477; ENSECAP00000019447; ENSECAG00000022001 |
Similar proteinsi
Cross-referencesi
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | F6YFY8 |
Genome annotation databases
Ensembli | ENSECAT00000023477; ENSECAP00000019447; ENSECAG00000022001 |
Organism-specific databases
VGNCi | VGNC:82072, ZNF317 |
Phylogenomic databases
GeneTreei | ENSGT00940000162241 |
HOGENOMi | CLU_002678_72_0_1 |
InParanoidi | F6YFY8 |
TreeFami | TF338497 |
Gene expression databases
Bgeei | ENSECAG00000022001, Expressed in inner cell mass and 22 other tissues |
ExpressionAtlasi | F6YFY8, baseline |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 9 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 13 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6YFY8_HORSE | |
Accessioni | F6YFY8Primary (citable) accession number: F6YFY8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 54 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |