UniProtKB - F6YCC0 (F6YCC0_HORSE)
Protein
Submitted name:
Cystatin A
Gene
CSTA
Organism
Equus caballus (Horse)
Status
Functioni
GO - Molecular functioni
- cysteine-type endopeptidase inhibitor activity Source: GO_Central
- protease binding Source: Ensembl
GO - Biological processi
- cell-cell adhesion Source: Ensembl
- keratinocyte differentiation Source: Ensembl
- peptide cross-linking Source: Ensembl
Keywordsi
Molecular function | Protease inhibitor, Thiol protease inhibitorARBA annotation |
Protein family/group databases
MEROPSi | I25.001 |
Names & Taxonomyi
Protein namesi | Submitted name: Cystatin AImported |
Gene namesi | Name:CSTAImported |
Organismi | Equus caballus (Horse)Imported |
Taxonomic identifieri | 9796 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Perissodactyla › Equidae › Equus › |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:16918, CSTA |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Extracellular region or secreted
- extracellular space Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
Plasma Membrane
- cornified envelope Source: Ensembl
Expressioni
Gene expression databases
Bgeei | ENSECAG00000024043, Expressed in zone of skin and 19 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 5 – 102 | CystatinInterPro annotationAdd BLAST | 98 |
Sequence similaritiesi
Belongs to the cystatin family.ARBA annotation
Phylogenomic databases
GeneTreei | ENSGT00940000155717 |
HOGENOMi | CLU_150234_2_1_1 |
InParanoidi | F6YCC0 |
OMAi | YYIKIRV |
OrthoDBi | 1647595at2759 |
TreeFami | TF333174 |
Family and domain databases
CDDi | cd00042, CY, 1 hit |
InterProi | View protein in InterPro IPR000010, Cystatin_dom IPR018073, Prot_inh_cystat_CS IPR001713, Prot_inh_stefin |
PANTHERi | PTHR11414, PTHR11414, 1 hit |
Pfami | View protein in Pfam PF00031, Cystatin, 1 hit |
PRINTSi | PR00295, STEFINA |
SMARTi | View protein in SMART SM00043, CY, 1 hit |
PROSITEi | View protein in PROSITE PS00287, CYSTATIN, 1 hit |
i Sequence
Sequence statusi: Complete.
F6YCC0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMSGGMPGGL TEARPATPEI QEIADRVKPQ LEEKTNQTYE EFKAVEYKTQ
60 70 80 90 100
VVAGTNYYIK VQVGDNNYIH LKIFKSLPQQ NESLTLTGYQ TDKRKDDELK
GF
Sequence databases
RefSeqi | XP_003363423.1, XM_003363375.3 |
Genome annotation databases
Ensembli | ENSECAT00000025834; ENSECAP00000021509; ENSECAG00000024043 |
GeneIDi | 100629524 |
KEGGi | ecb:100629524 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_003363423.1, XM_003363375.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
MEROPSi | I25.001 |
Proteomic databases
PaxDbi | F6YCC0 |
PRIDEi | F6YCC0 |
Genome annotation databases
Ensembli | ENSECAT00000025834; ENSECAP00000021509; ENSECAG00000024043 |
GeneIDi | 100629524 |
KEGGi | ecb:100629524 |
Organism-specific databases
CTDi | 1475 |
VGNCi | VGNC:16918, CSTA |
Phylogenomic databases
GeneTreei | ENSGT00940000155717 |
HOGENOMi | CLU_150234_2_1_1 |
InParanoidi | F6YCC0 |
OMAi | YYIKIRV |
OrthoDBi | 1647595at2759 |
TreeFami | TF333174 |
Gene expression databases
Bgeei | ENSECAG00000024043, Expressed in zone of skin and 19 other tissues |
Family and domain databases
CDDi | cd00042, CY, 1 hit |
InterProi | View protein in InterPro IPR000010, Cystatin_dom IPR018073, Prot_inh_cystat_CS IPR001713, Prot_inh_stefin |
PANTHERi | PTHR11414, PTHR11414, 1 hit |
Pfami | View protein in Pfam PF00031, Cystatin, 1 hit |
PRINTSi | PR00295, STEFINA |
SMARTi | View protein in SMART SM00043, CY, 1 hit |
PROSITEi | View protein in PROSITE PS00287, CYSTATIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | F6YCC0_HORSE | |
Accessioni | F6YCC0Primary (citable) accession number: F6YCC0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 27, 2011 |
Last sequence update: | December 11, 2019 | |
Last modified: | December 2, 2020 | |
This is version 60 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |