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Protein
Submitted name:

ALX homeobox 1

Gene

ALX1

Organism
Ornithorhynchus anatinus (Duckbill platypus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi134 – 193HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinPROSITE-ProRule annotationSAAS annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
ALX homeobox 1Imported
Gene namesi
Name:ALX1Imported
OrganismiOrnithorhynchus anatinus (Duckbill platypus)Imported
Taxonomic identifieri9258 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaMonotremataOrnithorhynchidaeOrnithorhynchus
Proteomesi
  • UP000002279 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Expressioni

Gene expression databases

BgeeiENSOANG00000006647 Expressed in 2 organ(s), highest expression level in female gonad

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9258.ENSOANP00000010601

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini132 – 192HomeoboxInterPro annotationAdd BLAST61
Domaini308 – 321OARInterPro annotationAdd BLAST14

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi308 – 321OARPROSITE-ProRule annotationAdd BLAST14

Sequence similaritiesi

Belongs to the paired homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
GeneTreeiENSGT00900000140809
InParanoidiF6Y859
OMAiSSCMLPR
OrthoDBiEOG091G0B1L
TreeFamiTF350743

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR033209 ALX1
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR003654 OAR_dom
PANTHERiPTHR24329:SF359 PTHR24329:SF359, 1 hit
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF03826 OAR, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS50803 OAR, 1 hit

Sequencei

Sequence statusi: Complete.

F6Y859-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDFLSEKFAL KSPPSKNSDF YMGAGGTLEH VMETLDNESF YSKTSGGKCV
60 70 80 90 100
QAFNPLQRAE HHVRLERTSP CQENNGTVNY GITKVEGQPL HTELNRAMDN
110 120 130 140 150
CNSLRMSPVK GLQEKGELDE LGDKCDSNVT SSKKRRHRTT FTSLQLEELE
160 170 180 190 200
KVFQKTHYPD VYVREQLALR TELTEARVQV WFQNRRAKWR KRERYGQIQQ
210 220 230 240 250
AKSHFAATYD ISVLPRTDSY PQIQNNLWAG NATGGSVVTS CMLPRDTSSC
260 270 280 290 300
MTPYSHSPRT DSGYTGFSNH QNQFSHVPLN NFFTDSLLSG ASNGHAFETK
310 320
PEFERRSSSI AVLRMKAKEH TANISWAM
Length:328
Mass (Da):37,234
Last modified:July 27, 2011 - v1
Checksum:i85321351C448FDF2
GO

Genome annotation databases

EnsembliENSOANT00000010603; ENSOANP00000010601; ENSOANG00000006647

Similar proteinsi

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9258.ENSOANP00000010601

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOANT00000010603; ENSOANP00000010601; ENSOANG00000006647

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
GeneTreeiENSGT00900000140809
InParanoidiF6Y859
OMAiSSCMLPR
OrthoDBiEOG091G0B1L
TreeFamiTF350743

Gene expression databases

BgeeiENSOANG00000006647 Expressed in 2 organ(s), highest expression level in female gonad

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR033209 ALX1
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR003654 OAR_dom
PANTHERiPTHR24329:SF359 PTHR24329:SF359, 1 hit
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF03826 OAR, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit
PS50803 OAR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiF6Y859_ORNAN
AccessioniPrimary (citable) accession number: F6Y859
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: November 7, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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