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Protein
Submitted name:

CD4 molecule

Gene

CD4

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD4 moleculeImported
Gene namesi
Name:CD4Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 6

Organism-specific databases

VGNCiVGNC:16267 CD4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei400 – 426HelicalSequence analysisAdd BLAST27

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500335118726 – 461Sequence analysisAdd BLAST436

Proteomic databases

PaxDbiF6Y6X8

Expressioni

Gene expression databases

BgeeiENSECAG00000009049

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000007248

Structurei

3D structure databases

SMRiF6Y6X8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 119Ig-likeInterPro annotationAdd BLAST100

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK9F Eukaryota
ENOG410YWI4 LUCA
GeneTreeiENSGT00390000001745
InParanoidiF6Y6X8
OMAiPEAGMWQ
OrthoDBiEOG091G0AZL
TreeFamiTF335974

Family and domain databases

Gene3Di2.60.40.10, 4 hits
InterProiView protein in InterPro
IPR000973 CD4
IPR015274 CD4-extracel
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR008424 Ig_C2-set
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR013151 Immunoglobulin
IPR021963 Tcell_CD4_Cterm
PANTHERiPTHR11422:SF0 PTHR11422:SF0, 1 hit
PfamiView protein in Pfam
PF05790 C2-set, 2 hits
PF09191 CD4-extracel, 1 hit
PF00047 ig, 1 hit
PF12104 Tcell_CD4_C, 1 hit
PRINTSiPR00692 CD4TCANTIGEN
SMARTiView protein in SMART
SM00409 IG, 3 hits
SM00406 IGv, 1 hit
SUPFAMiSSF48726 SSF48726, 4 hits
PROSITEiView protein in PROSITE
PS50835 IG_LIKE, 1 hit

Sequencei

Sequence statusi: Complete.

F6Y6X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDRGTSFGHL LLLLQLALLP AVTQGREVVL GKAGETVELP CQGSQKKNVF
60 70 80 90 100
FNWKYPSEVK ILGGQRTWWV KGNTKLKDRI ESKTTLWDQG SFPLIIKYLE
110 120 130 140 150
ITDSGTYICE VEDKKTEVEL LVFRLTANSH THSSIRLLLG QNLTLTLESP
160 170 180 190 200
SGSNPSVQWK GPRHQNTTQG SRFLLKLGLQ DSGTWTCTVS KDQKTLVFNI
210 220 230 240 250
NILVLAFQKV SRTVYAKEGT QAEFSFPLTF ADENLSGELQ WQAEGASSQQ
260 270 280 290 300
KWISFSSDNR KVSVTGVSSH LKLQVEEMLP LRFKLLQALP KHAGSGKLRL
310 320 330 340 350
FLAKGELQQE VNLVVMRLTR SQNDVTCQVL GPSSPKLMLS LKLENQTDQT
360 370 380 390 400
AKVSNSQKLV KVPDPETGTW QCLLSDNGKV LLESKIEVLA TSFPQASPKL
410 420 430 440 450
LAAVLGGVAG LLLFTGFFIF CCVKCWHRRR QAERMSQIKR LLSEKKTCQC
460
HHRFQKTVSP V
Length:461
Mass (Da):51,558
Last modified:July 27, 2011 - v1
Checksum:i73DFFD4D16CF47CB
GO

Genome annotation databases

EnsembliENSECAT00000009509; ENSECAP00000007248; ENSECAG00000009049

Similar proteinsi

Entry informationi

Entry nameiF6Y6X8_HORSE
AccessioniPrimary (citable) accession number: F6Y6X8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: June 20, 2018
This is version 44 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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