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Protein
Submitted name:

Tau tubulin kinase 2

Gene

TTBK2

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Tau tubulin kinase 2Imported
Gene namesi
Name:TTBK2Imported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus
Proteomesi
  • UP000002281 Componenti: Chromosome 1

Organism-specific databases

VGNCiVGNC:24607 TTBK2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiF6Y633

Expressioni

Gene expression databases

BgeeiENSECAG00000024034 Expressed in 3 organ(s), highest expression level in prefrontal cortex

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000021545

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 284Protein kinaseInterPro annotationAdd BLAST264

Phylogenomic databases

eggNOGiKOG1164 Eukaryota
ENOG410XPGP LUCA
GeneTreeiENSGT00920000148982
InParanoidiF6Y633
KOiK08815
OMAiNGELFHC
OrthoDBiEOG091G03H8
TreeFamiTF351646

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

F6Y633-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGGGEQPDI LSVGILVKER WKVLRKIGGG GFGEIYDALD MLTRENVALK
60 70 80 90 100
VESAQQPKQV LKMEVAVLKK LQGKDHVCRF IGCGRNDRFN YVVMQLQGRN
110 120 130 140 150
LADLRRSQSR GTFTISTTLR LGRQILESIE SIHSVGFLHR DIKPSNFAMG
160 170 180 190 200
RFPSTCRKCY MLDFGLARQF TNSCGDVRPP RAVAGFRGTV RYASINAHRN
210 220 230 240 250
REMGRHDDLW SLFYMLVEFV VGQLPWRKIK DKEQVGSIKE RYDHRLMLKH
260 270 280 290 300
LPPEFSMFLD HISSLDYFTK PDYQLLTSVF DNSIKTFGVI ESDPFDWEKT
310 320 330 340 350
GADGSLTTTT TSATPQLHTR LTPAAIGIAN ATPIPGDLLR ENTDEVFPDE
360 370 380 390 400
QLSDGENGIP VGVSPDKLPG SLGHPRPQEK DVWEEMDANR NKIKLGICKA
410 420 430 440 450
ATEEENSHGQ PNGILNAPSI GSPIRVRSEI TQPDRDVPLV RKLRSIHSFE
460 470 480 490 500
LEKRLTLEPK PDTDKFLEIC LEKMQKDSSA GKESILPALL HKPCVPAVSR
510 520 530 540 550
TDHIWHFDEE YLPDASKPAS ANTAEQADGV GSNGFIAVNL SSCKQEVDSK
560 570 580 590 600
EWVIVDKEQD LRDFRTNEAL GCKTTGSPSD EEPEVLQVLE ESPQDEKLRL
610 620 630 640 650
GPWAENNHLK KETSGVILAL SGECPATAAS EQYTDRLELQ AGAASQFIAV
660 670 680 690 700
TPTSPMEAQA EGPLTAITIP RPSVASTQST SGSFHYGQQP EKKDLQPVEP
710 720 730 740 750
TVELYSPREN FSGLVVTEGE PPSGGSRTDF GLQIDHIGHD MLPNVRECDR
760 770 780 790 800
SQDLGPKDIP DHNRLAVREC ESLPVETEGK STLLGSENED AKLSKGQHYM
810 820 830 840 850
EISSLPGDLV PMERDHSAPT EPFDVTKTQT FSVVPNQDKN HEIMKLLAVR
860 870 880 890 900
TSEISPRVID PHVEGHIGQV AAMQKSKLSK DDDIKSEDFP GHQGDLSTFL
910 920 930 940 950
HQEGKREKIV HRNGELFPCV SESEPCPPSR KDVVRSSFVT RHSRIPVLAQ
960 970 980 990 1000
EIDLTFESSS PVSAKEKLLQ KKAYQPDLVK LLVEKRQLKS FLGDLSSASD
1010 1020 1030 1040 1050
KLLEERLATV PPPFSEEEVF TPFSRLAVDS HLSRSAEDSF LSPIISQSRK
1060 1070 1080 1090 1100
SKIPRPVSWV NTDQVSSSTS SQFLPRPPPG KPPTRPGVEA RLRRYKVLGS
1110 1120 1130 1140 1150
SNSDSDLFSR LAQILQNGSQ KPRSTTQCKS PGSPHNPKTP PKSPVVPRRS
1160 1170 1180 1190 1200
PSASPRSSSL PRTSSSSPSR AGRPHHDQRS SSPHLGRSKS PPSHSGSSSS
1210 1220 1230 1240
RRSCQQEHCK PSKNSLKGSG SLHHHSASTK APPGKSKSAS KLSR
Length:1,244
Mass (Da):137,375
Last modified:July 27, 2011 - v1
Checksum:iBD757CE0C6DD0413
GO

Sequence databases

RefSeqiXP_001503269.1, XM_001503219.4

Genome annotation databases

EnsembliENSECAT00000025875; ENSECAP00000021545; ENSECAG00000024034
GeneIDi100056539
KEGGiecb:100056539

Similar proteinsi

Entry informationi

Entry nameiF6Y633_HORSE
AccessioniPrimary (citable) accession number: F6Y633
Entry historyiIntegrated into UniProtKB/TrEMBL: July 27, 2011
Last sequence update: July 27, 2011
Last modified: September 12, 2018
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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